Výsledky vyhledávání - "Gonzalo F. Mayol"

Solvent Sites Improve Docking Performance of Protein-Protein Complexes and Protein-Protein Interface-Targeted Drugs

Autor: Gonzalo F. Mayol, Lucas A. Defelipe, Juan Pablo Arcon, Adrian G. Turjanski, Marcelo A. Marti

Publikováno v: Journal of chemical information and modeling. 62(15)

Protein-protein interactions (PPIs) are essential, and modulating their function through PPI-targeted drugs is an important research field. PPI sites are shallow protein surfaces readily accessible to the solvent, thus lacking a proper pocket to fit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3c20196d3ba1f876d597052c870d0b8
https://pubmed.ncbi.nlm.nih.gov/35853201

Zobrazit plný text záznamu

Evidence of nuclear transport mechanisms in the protozoan parasite Giardia lamblia

Autor: Maria Victoria Revuelta, María C. Touz, Andrea S. Rópolo, Gonzalo F. Mayol, Agostina Salusso

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Nuclear-cytoplasmic trafficking of proteins is a highly regulated process that modulates multiple biological processes in eukaryotic cells. In Giardia lamblia, shuttling has been described from the cytoplasm to nuclei of proteins during the biologica

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b46c3e7018e976e2a9c1768c3d3f63
https://pubmed.ncbi.nlm.nih.gov/31672613

Zobrazit plný text záznamu

Endoplasmic reticulum is the sorting core facility in the Golgi-lacking protozoan Giardia lamblia

Autor: Emiliano Zamponi, Gonzalo F. Mayol, Adriana Lanfredi-Rangel, Staffan G. Svärd, Nahuel Zamponi, María C. Touz

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Our understanding of protein and lipid trafficking in eukaryotic cells has been challenged by the finding of different forms of compartmentalization and cargo processing in protozoan parasites. Here, we show that, in the absence of a Golgi compartmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23bb625f99f1dd48ce0a74fece33c15e
Wiley Online Library

Zobrazit plný text záznamu

SUMOylation and deimination of proteins: Two epigenetic modifications involved in Giardia encystation

Autor: María C. Merino, María C. Pistoresi-Palencia, Belkys A. Maletto, Maria Romina Rivero, Gonzalo F. Mayol, María C. Touz, Cecilia V. Vranych, Nahuel Zamponi, Andrea S. Rópolo

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

SUMOylation, a post-translational modification of proteins, has been recently described as vital in eukaryotic cells. In a previous work, we analyzed the role of SUMO protein and the genes encoding the putative enzymes of the SUMOylation pathway in t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef1b28f24d2fb1c9800efc0516b14bdf

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání