Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Gonzalo Duran"'
Autor:
Tim E. Moors, Daniel Mona, Stefan Luehe, Gonzalo Duran-Pacheco, Liz Spycher, Olaf Mundigl, Klaus Kaluza, Sylwia Huber, Melanie N. Hug, Thomas Kremer, Mirko Ritter, Sebastian Dziadek, Gregor Dernick, Wilma D. J. van de Berg, Markus Britschgi
Publikováno v:
Acta Neuropathologica Communications, Vol 10, Iss 1, Pp 1-22 (2022)
Abstract Based on immunostainings and biochemical analyses, certain post-translationally modified alpha-synuclein (aSyn) variants, including C-terminally truncated (CTT) and Serine-129 phosphorylated (pSer129) aSyn, are proposed to be involved in the
Externí odkaz:
https://doaj.org/article/7462bb934f3b4b95bbbd0d8a65c4f8ea
Autor:
Anna Lisa Gündner, Gonzalo Duran-Pacheco, Silke Zimmermann, Iris Ruf, Tim Moors, Karlheinz Baumann, Ravi Jagasia, Wilma D.J. van de Berg, Thomas Kremer
Publikováno v:
Neurobiology of Disease, Vol 121, Iss , Pp 205-213 (2019)
Synucleinopathies including Parkinson's disease (PD) and Dementia with Lewy bodies (DLB) are characterized by the accumulation of abnormal α-synuclein in intraneuronal inclusions, named Lewy bodies. Mutations in GBA1, the gene encoding the lysosomal
Externí odkaz:
https://doaj.org/article/f283be9ad4f1434083071b1664441dc4
Autor:
Stefan Grathwohl, Emmanuel Quansah, Nazia Maroof, Jennifer A. Steiner, Liz Spycher, Fethalla Benmansour, Gonzalo Duran-Pacheco, Juliane Siebourg-Polster, Krisztina Oroszlan-Szovik, Helga Remy, Markus Haenggi, Marc Stawiski, Matthias Selhausen, Pierre Mailver, Andreas Wolfert, Thomas Emrich, Zachary Madaj, Arel Su, Martha L. Escobar Galvis, Christoph Mueller, Annika Herrmann, Patrik Brundin, Markus Britschgi
Publikováno v:
Free Neuropathology, Vol 2 (2021)
Background: In some people with Parkinson’s disease (PD), a-synuclein (αSyn) accumulation may begin in the enteric nervous system (ENS) decades before development of brain pathology and disease diagnosis. Objective: To determine how different t
Externí odkaz:
https://doaj.org/article/807c1d2bbbe0427e855cfe53e1014799
Autor:
Manaswini Sivaramakrishnan, Kathleen D. McCarthy, Sébastien Campagne, Sylwia Huber, Sonja Meier, Angélique Augustin, Tobias Heckel, Hélène Meistermann, Melanie N. Hug, Pascale Birrer, Ahmed Moursy, Sarah Khawaja, Roland Schmucki, Nikos Berntenis, Nicolas Giroud, Sabrina Golling, Manuel Tzouros, Balazs Banfai, Gonzalo Duran-Pacheco, Jens Lamerz, Ying Hsiu Liu, Thomas Luebbers, Hasane Ratni, Martin Ebeling, Antoine Cléry, Sergey Paushkin, Adrian R. Krainer, Frédéric H.-T. Allain, Friedrich Metzger
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Small molecules correcting the splicing deficit of the survival of motor neuron 2 (SMN2) gene have been identified as having therapeutic potential. Here, the authors provide evidence that SMN2 mRNA forms a ribonucleoprotein complex that can be specif
Externí odkaz:
https://doaj.org/article/86ed63c63e664f938352b802e813bfcc
Autor:
Florence Allantaz, Donavan T Cheng, Tobias Bergauer, Palanikumar Ravindran, Michel F Rossier, Martin Ebeling, Laura Badi, Bernhard Reis, Hans Bitter, Matilde D'Asaro, Alberto Chiappe, Sriram Sridhar, Gonzalo Duran Pacheco, Michael E Burczynski, Denis Hochstrasser, Jacky Vonderscher, Thomas Matthes
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29979 (2012)
Blood consists of different cell populations with distinct functions and correspondingly, distinct gene expression profiles. In this study, global miRNA expression profiling was performed across a panel of nine human immune cell subsets (neutrophils,
Externí odkaz:
https://doaj.org/article/a09b488f612142eb9150e0324b41df65
Autor:
Daniel Mäusezahl, Andri Christen, Gonzalo Duran Pacheco, Fidel Alvarez Tellez, Mercedes Iriarte, Maria E Zapata, Myriam Cevallos, Jan Hattendorf, Monica Daigl Cattaneo, Benjamin Arnold, Thomas A Smith, John M Colford
Publikováno v:
PLoS Medicine, Vol 6, Iss 8, p e1000125 (2009)
Solar drinking water disinfection (SODIS) is a low-cost, point-of-use water purification method that has been disseminated globally. Laboratory studies suggest that SODIS is highly efficacious in inactivating waterborne pathogens. Previous field stud
Externí odkaz:
https://doaj.org/article/7bd10120cae64f7d817e56b42bb8debd
Autor:
Gonzalo Duran, Lucas, Emilia Beilman, María, Natali Quiroga, Araceli, Cruz, Magdalena, Vanesa Millan, Alejandra, Johanna Ojeda, Micaela, Ciccioli, Fabiana, Montenegro Fernandez, Micaela Giselle, Monrroy Miro, Wendy Estefany, Trinidad Malisia, Valentina, Antonio Grassi, Nicolas, Zelaya De Leon, Nazareno Iñaki, Ezequiel Espinoza, Franco, Otamendi, Marina, Zorzano Osinalde, Paula, Petasny, Marcos
Publikováno v:
Revista de la Facultad de Medicina Humana; Jan-Mar2024, Vol. 24 Issue 1, p58-64, 7p
Publikováno v:
Microbial Biotechnology, Vol 17, Iss 10, Pp n/a-n/a (2024)
Abstract Phthalic acid esters (PAEs) are synthetic diesters derived from o‐phthalic acid, commonly used as plasticizers. These compounds pose significant environmental and health risks due to their ability to leach into the environment and act as e
Externí odkaz:
https://doaj.org/article/9adad56d871941dbb5800c84d38c126e
Autor:
Pacheco, Gonzalo Durán, Christen, Andri, Arnold, Ben, Hattendorf, Jan, Colford,, John M., Smith, Thomas A., Mäusezahl, Daniel
Publikováno v:
Journal of Health, Population and Nutrition, 2011 Dec 01. 29(6), 552-559.
Externí odkaz:
https://www.jstor.org/stable/23500196
Publikováno v:
Frontiers in Neuroscience, Vol 15 (2021)
Frontiers in Neuroscience
Frontiers in Neuroscience
Background: Trajectories of comorbidities among individuals at risk of Alzheimer’s disease (AD) may differ from those aging without AD clinical syndrome. Therefore, characterizing the comorbidity burden and pattern associated with AD risk may facil