Zobrazeno 1 - 5
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pro vyhledávání: '"Gonzalo Barrera-Hernandez"'
Publikováno v:
DNA and Cell Biology. 17:743-750
Thyroid hormone nuclear receptors (TRs) are ligand-dependent transcription factors which regulate growth, differentiation, and development. The molecular mechanism by which TRs mediated these effects remains unclear. A prevailing hypothesis is that T
Autor:
Susan B. Nunez, Sheue yann Cheng, Gonzalo Barrera-Hernandez, Paul H. Driggers, James H. Segars, Chia Lin Yu
Publikováno v:
Biochemical and Biophysical Research Communications. 239:617-620
The estrogen receptor (ER) is a ligand-dependent transcription factor which regulates growth, development, differentiation and reproduction. To test the hypothesis that the diverse effects of the ER could be mediated by interacting with other transcr
Publikováno v:
Journal of Biological Chemistry. 271:9969-9975
We have previously reported that albumin gene transcription is reduced in diabetes mellitus (DM). The present study explored the mechanism by which albumin gene transcription is down-regulated in DM. Deletional studies and displacement of factors bin
Publikováno v:
Molecular and cellular biology. 20(12)
Myc and Mad are basic helix-loop-helix leucine zipper (bHLH-LZ) proteins that heterodimerize with Max to bind DNA and thereby influence the transcription of Myc-responsive genes. Myc-Max dimers transactivate whereas Mad-Max-mSin3 complexes repress My
Publikováno v:
Diabetes. 45(9)
Diabetes decreases transcription of the albumin gene. The role of hyperglycemia in mediating this suppression of albumin gene activity is unclear. To study the effect of glucose in vivo, we treated diabetic rats with phlorizin or vanadate, two agents