Daily glucocorticoids promote glioblastoma growth and circadian synchrony to the host.

Autor: Gonzalez-Aponte MF; Department of Biology, Division of Biology and Biomedical Sciences, Washington University in St. Louis, St. Louis, MO 63130, USA., Damato AR; Department of Biology, Division of Biology and Biomedical Sciences, Washington University in St. Louis, St. Louis, MO 63130, USA., Simon T; Department of Biology, Division of Biology and Biomedical Sciences, Washington University in St. Louis, St. Louis, MO 63130, USA., Aripova N; Department of Biology, Division of Biology and Biomedical Sciences, Washington University in St. Louis, St. Louis, MO 63130, USA., Darby F; Department of Biology, Division of Biology and Biomedical Sciences, Washington University in St. Louis, St. Louis, MO 63130, USA., Jeon MS; Department of Surgery, Division of Public Health Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA; Siteman Cancer Center Biostatistics Shared Resource, Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA., Luo J; Department of Surgery, Division of Public Health Sciences, Washington University School of Medicine, St. Louis, MO 63110, USA; Siteman Cancer Center Biostatistics Shared Resource, Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA., Rubin JB; Department of Pediatrics, St. Louis Children's Hospital, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Neuroscience, Washington University School of Medicine, St. Louis, MO 63110, USA., Herzog ED; Department of Biology, Division of Biology and Biomedical Sciences, Washington University in St. Louis, St. Louis, MO 63130, USA. Electronic address: herzog@wustl.edu.

Publikováno v: Cancer cell [Cancer Cell] 2024 Dec 06. Date of Electronic Publication: 2024 Dec 06.

Circadian regulation of MGMT expression and promoter methylation underlies daily rhythms in TMZ sensitivity in glioblastoma.

Autor: Gonzalez-Aponte MF; Department of Biology, Washington University in St. Louis, St. Louis, MO, USA., Damato AR; Department of Biology, Washington University in St. Louis, St. Louis, MO, USA., Trebucq LL; Laboratorio de Cronobiología, Universidad Nacional de Quilmes-CONICET, Buenos Aires, Argentina., Simon T; Department of Biology, Washington University in St. Louis, St. Louis, MO, USA., Cárdenas-García SP; Department of Biology, Washington University in St. Louis, St. Louis, MO, USA., Cho K; Departments of Chemistry and Medicine, Washington University in St. Louis, St. Louis, MO, USA.; Center for Metabolomics and Isotope Tracing, Washington University in St. Louis, St. Louis, MO, USA., Patti GJ; Departments of Chemistry and Medicine, Washington University in St. Louis, St. Louis, MO, USA.; Center for Metabolomics and Isotope Tracing, Washington University in St. Louis, St. Louis, MO, USA., Golombek DA; Laboratorio de Cronobiología, Universidad Nacional de Quilmes-CONICET, Buenos Aires, Argentina.; Laboratorio Interdisciplinario del Tiempo (LITERA), Universidad de San Andrés, B1644BID, Victoria, Buenos Aires, Argentina., Chiesa JJ; Laboratorio de Cronobiología, Universidad Nacional de Quilmes-CONICET, Buenos Aires, Argentina., Rubin JB; Department of Pediatrics, Washington University School of Medicine, St Louis, MO, USA.; Department of Neuroscience, Washington University School of Medicine, St Louis, MO, USA., Herzog ED; Department of Biology, Washington University in St. Louis, St. Louis, MO, USA. herzog@wustl.edu.

Publikováno v: Journal of neuro-oncology [J Neurooncol] 2024 Feb; Vol. 166 (3), pp. 419-430. Date of Electronic Publication: 2024 Jan 26.

Circadian Rhythms and Astrocytes: The Good, the Bad, and the Ugly.

Autor: Hastings MH; Division of Neurobiology, Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom; email: mha@mrc-lmb.cam.ac.uk., Brancaccio M; UK Dementia Research Institute and Department of Brain Sciences, Imperial College London, London, United Kingdom., Gonzalez-Aponte MF; Department of Biology, Division of Biology and Biomedical Sciences, Washington University in St. Louis, St. Louis, Missouri, USA; email: herzog@wustl.edu., Herzog ED; Department of Biology, Division of Biology and Biomedical Sciences, Washington University in St. Louis, St. Louis, Missouri, USA; email: herzog@wustl.edu.

Publikováno v: Annual review of neuroscience [Annu Rev Neurosci] 2023 Jul 10; Vol. 46, pp. 123-143. Date of Electronic Publication: 2023 Mar 28.