Clotting factor genes are associated with preeclampsia in high altitude pregnant women in the Peruvian Andes

Autor: Chen Jw, Celeste Eng, Malena Hurtado G, Maria A. Nieves-Colón, Poletti G, Enriquez Lencinas Le, Gonzalez Burchard E, Ortiz Tello P, Scott Huntsman, Moreno Estrada A, Condori Salas R, Genevieve L. Wojcik, Badillo Rivera Km, Gallo C, Cebrecos R, Erin Rawls, Sandoval Mendoza K, Alexandra Sockell, Zhang Et, Carlos Bustamante, Manzaneda Choque Jc, Manzaneda Choque Fp, Yabar Pilco Gp, Villanueva Davalos, Barker Jc, Christopher R. Gignoux

Study questionWhat is the genetic basis of preeclampsia in Andean families residing at high altitudes?Summary answerA top candidate region associated with preeclampsia containing clotting factor genesPROZ, F7andF10was found on chromosome 13 of the fe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0a58b3391411227a6bc302ba7fac379
https://doi.org/10.1101/2021.05.20.21257549

Genome-wide association study of breast cancer in Latinas identifies novel protective variants on 6q25.

Autor: Fejerman L; Division of General Internal Medicine, Department of Medicine, Institute of Human Genetics, University of California San Fancisco, San Francisco, California 94158, USA., Ahmadiyeh N; Department of Surgery, University of California San Francisco, San Francisco, California 94122, USA., Hu D; Division of General Internal Medicine, Department of Medicine, Institute of Human Genetics, University of California San Fancisco, San Francisco, California 94158, USA., Huntsman S; Division of General Internal Medicine, Department of Medicine, Institute of Human Genetics, University of California San Fancisco, San Francisco, California 94158, USA., Beckman KB; University of Minnesota Genomics Center, Minneapolis, Minnesota 55455, USA., Caswell JL; Division of General Internal Medicine, Department of Medicine, Institute of Human Genetics, University of California San Fancisco, San Francisco, California 94158, USA., Tsung K; Department of Surgery, University of California San Francisco, San Francisco, California 94122, USA., John EM; 1] Cancer Prevention Institute of California, Fremont, California 94538, USA [2] Division of Epidemiology, Department of Health Research and Policy, Stanford Cancer Institute, Stanford University School of Medicine, Palo Alto, California 94305, USA., Torres-Mejia G; National Institute of Public Health, Cuernavaca 62100, Mexico., Carvajal-Carmona L; 1] Department of Biochemistry and Molecular Medicine, University of California Davis, Davis, California 95616, USA [2] Research Group, Citogenética Filogenia y Evolución de Poblaciones, University of Tolima, Ibagué 7652000, Colombia., Echeverry MM; Department of Biochemistry and Molecular Medicine, University of California Davis, Davis, California 95616, USA., Tuazon AM; Department of Biochemistry and Molecular Medicine, University of California Davis, Davis, California 95616, USA., Ramirez C; Research Group, Citogenética Filogenia y Evolución de Poblaciones, University of Tolima, Ibagué 7652000, Colombia., Gignoux CR; Department of Genetics, Stanford University, Palo Alto, California 94305, USA., Eng C; Division of Pulmonary and Critical Care, Department of Medicine, Institute for Human Genetics, University of California San Francisco, San Francisco, California 94158, USA., Gonzalez-Burchard E; Division of Pulmonary and Critical Care, Department of Medicine, Institute for Human Genetics, University of California San Francisco, San Francisco, California 94158, USA., Henderson B; Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA., Le Marchand L; University of Hawaii Cancer Center, Honolulu, Hawaii 96813, USA., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA., Hou L; Department of Preventive Medicine, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA., Agalliu I; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA., Kraft P; Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Lindström S; Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Perez-Stable EJ; Division of General Internal Medicine, Department of Medicine, Institute of Human Genetics, University of California San Fancisco, San Francisco, California 94158, USA., Haiman CA; Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA., Ziv E; Division of General Internal Medicine, Department of Medicine, Institute of Human Genetics, University of California San Fancisco, San Francisco, California 94158, USA.

Publikováno v: Nature communications [Nat Commun] 2014 Oct 20; Vol. 5, pp. 5260. Date of Electronic Publication: 2014 Oct 20.

Ancestry-related assortative mating in Latino populations.

Autor: Risch N; Institute for Human Genetics, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143, USA. rischn@humgen.ucsf.edu, Choudhry S, Via M, Basu A, Sebro R, Eng C, Beckman K, Thyne S, Chapela R, Rodriguez-Santana JR, Rodriguez-Cintron W, Avila PC, Ziv E, Gonzalez Burchard E

Publikováno v: Genome biology [Genome Biol] 2009; Vol. 10 (11), pp. R132. Date of Electronic Publication: 2009 Nov 20.

The genomic footprint of social stratification in admixing American populations.

Autor: Mas-Sandoval, Alex, Mathieson, Sara, Fumagalli, Matteo

Publikováno v: eLife; 1/9/2024, p1-23, 23p

Genetic risk prediction in Hispanics/Latinos: milestones, challenges, and social-ethical considerations.

Autor: Maldonado, Betzaida L., Piqué, Daniel G., Kaplan, Robert C., Claw, Katrina G., Gignoux, Christopher R.

Publikováno v: Journal of Community Genetics; Dec2023, Vol. 14 Issue 6, p543-553, 11p