Pharmacological inhibition of cathepsin S and of NSPs-AAP-1 (a novel, alternative protease driving the activation of neutrophil serine proteases)

Autor: Domain, Roxane, Seren, Seda, Jerke, Uwe, Makridakis, Manousos, Chen, Kuan-Ju, Zoidakis, Jérôme, Rhimi, Moez, Zhang, Xian, Bonvent, Tillia, Croix, Cécile, Gonzalez, Loïc, Li, Dedong, Basso, Jessica, Paget, Christophe, Viaud-Massuard, Marie-Claude, Lalmanach, Gilles, Shi, Guo-Ping, Aghdassi, Ali, Vlahou, Antonia, McDonald, Patrick P., Couillin, Isabelle, Williams, Rich, Kettritz, Ralph, Korkmaz, Brice

Publikováno v: In Biochemical Pharmacology November 2024 229

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Description of a Murine Model of Pneumocystis Pneumonia.

Autor: Chesnay, Adélaïde, Gonzalez, Loïc, Parent, Christelle, Desoubeaux, Guillaume, Baranek, Thomas

Publikováno v: Mycopathologia; Jun2024, Vol. 189 Issue 3, p1-11, 11p

Phenotypical and functional alteration of unconventional T cells in severe COVID-19 patients

Autor: Jouan, Youenn, Guillon, Antoine, Gonzalez, Loïc, Perez, Yonatan, Boisseau, Chloé, Ehrmann, Stephan, Ferreira, Marion, Daix, Thomas, Jeannet, Robin, François, Bruno, Dequin, Pierre-François, Si-Tahar, Mustapha, Baranek, Thomas, Paget, Christophe

Publikováno v: Journal of Experimental Medicine
Journal of Experimental Medicine, Rockefeller University Press, 2020, 217 (12), ⟨10.1084/jem.20200872⟩
The Journal of Experimental Medicine

This study reveals profound alteration in biology of blood unconventional T cells (MAIT, iNKT, and γδT) in severe COVID-19. Highly activated MAIT cells are found in abundance in the airways of mechanically ventilated patients. Activation levels of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ebebef3fe25fb150e2a76de44e26f2a7
https://hal-univ-tours.archives-ouvertes.fr/hal-03365046

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