Long-term safety and efficacy of tezepelumab in people with severe, uncontrolled asthma (DESTINATION): a randomised, placebo-controlled extension study

Autor: Hetzel, Jorge Lima, Fiterman, Jussara, Souza Machado, Adelmir, Antila, Martti Anton, Lima, Marina Andrade, Minamoto, Suzana Erico Tanni, Blanco, Daniela Cavalet, Bezerra, Patricia Gomes de Matos, Houle, Pierre-Alain, Lemiere, Catherine, Melenka, Lyle S, Leigh, Richard, Mitchell, Patrick, Anees, Syed, Pek, Bonavuth, Chouinard, Guy, Cheema, Amarjit S, Yang, William Ho-Ching, Philteos, George, Chanez, Pascal, Bourdin, Arnaud, Devouassoux, Gilles, Taille, Camille, De Blay, Frédéric, Leroyer, Christophe, Beurnier, Antoine, Garcia, Gilles, Girodet, Pierre-Olivier, Blanc, François-Xavier, Magnan, Antoine, Wanin, Stéphanie, Just, Jocelyne, Linde, Richard, Zielen, Stefan, Förster, Karin, Geßner, Christian, Jandl, Margret, Buhl, Roland Otto, Korn, Stephanie, Kornmann, Marc Oliver, Linnhoff, Anneliese, Ludwig-Sengpiel, Andrea, Ehlers, Martin, Schmoller, Tibor, Steffen, Heiner, Hoffmann, Martin, Kirschner, Joachim, Schmidt, Olaf, Welte, Tobias, Temme, Hilke, Wand, Ori, Bar-Shai, Amir, Izbicki, Gabriel, Berkman, Neville, Fink, Gershon, Shitrit, David, Adir, Yochai, Kuna, Piotr, Rewerska, Barbara, Pisarczyk-Bogacka, Ewa, Kurbacheva, Oksana, Mikhailov, Sergey L, Vasilev, Maksim, Emelyanov, Alexander, Wali, Siraj, Albanna, Amr, van Zyl-Smit, Richard, Abdullah, Ismail, Bernhardi, David, Hoosen, Farzana, Irusen, Elvis, Kalla, Ismail, Lakha, Deepak, Mitha, Essack, Naidoo, Visvakuren, Nell, Haylene, Padayachee, Trevenesan, Reddy, Jeevren, Petrick, Friedrich, van der Walt, Eugene, Vawda, Zubar Fazal Ahmed, Park, Hae-Sim, Lee, Sang Haak, Kim, Mi-Kyeong, Park, Jung-Won, Cho, You Sook, Lee, Byung Jae, Chang, Yoon-Seok, Park, Choon-Sik, Lee, Kwan Ho, Lee, Sook Young, Yoon, HyoungKyu, Sohn, Kyoung Hee, Park, Myung Jae, Min, Kyung Hoon, Cho, Young Joo, Park, Han Ki, Lee, YongChul, Lee, Jaechun, Sheu, Chau-Chyun, Tu, Chih-Yen, Lee, Kang-Yun, Bavbek, Sevim, Gemicioglu, Bilun, Ediger, Dane, Kalkan, Ilkay Koca, Makieieva, Nataliia, Ostrovskyy, Mykola, Dytyatkovs'ka, Yevgeniya, Mostovoy, Yuriy Mykhaylovych, Lebed, Kyrylo, Yakovenko, Oleh, Adams, Atoya, Mooring, Timothy, Torres Jr, Louis, Sexton, Marvin, Thompson, Ernest, Bernstein, Jonathan A, Lisi, Paul, Chappel, Christopher M, Cole, Jeremy, Greenwald, Gary I, Jones, Conigliaro, Klein, Ryan Mitchell, Pham, David N, Spangenthal, Selwyn, Weinstein, Steven F, Windom, Hugh H, Kao, Neil L, Leong, Mila A, Mehta, Vinay, Moore, Wendy C, Bhat, Saligrama, Aish, Bassil, Meltzer, Steven M, Corren, Jonathan, Moss, Mark H, Kerwin, Edward M, Delgado, John Palsted, Lucksinger, Gregg Hudson, Thompson, Charles A, Chupp, Geoffrey, Alpizar, Sady A, Vadgama, Sanjay Virgi, Zafar, Zahid, Jacobs, Joshua S, Lugogo, NJira, Jain, Neal, Sher, Lawrence D, Andrawis, Nabil S, Fuentes, David, Boren, Eric Jason, Gonzalez, Erika G, Talreja, Neetu, Durrani, Sheharyar Sandy, Israel, Elliot, Sekhsaria, Sudhir, DeLeon, Samuel, Shukla, Mayank, Totszollosy Tarpay, Martha M, Fakih, Faisal, Hudes, Golda, Tillinghast, Jeffrey P, Korenblat, Phillip E, Shenoy, Kartik, Que, Loretta, Kureishy, Shahrukh Ahmad, Umeh, Fred Chukwuemeka, Nguyen, Vinh Nhu, Chu, Hanh Thi, Nguyen, Thuy Thi Dieu, Menzies-Gow, Andrew ^*, Wechsler, Michael E, Brightling, Christopher E, Bednarczyk, Artur, Ponnarambil, Sandhia, Caveney, Scott, Almqvist, Gun, Gołąbek, Monika, Simonsson, Linda, Lawson, Kaitlyn, Bowen, Karin, Colice, Gene

Publikováno v: In The Lancet Respiratory Medicine May 2023 11(5):425-438

Long-term safety and efficacy of tezepelumab in people with severe, uncontrolled asthma (DESTINATION): a randomised, placebo-controlled extension study

Autor: Menzies-Gow, Andrew, Wechsler, Michael E, Brightling, Christopher E, Korn, Stephanie, Corren, Jonathan, Israel, Elliot, Chupp, Geoffrey, Bednarczyk, Artur, Ponnarambil, Sandhia, Caveney, Scott, Almqvist, Gun, Gołąbek, Monika, Simonsson, Linda, Lawson, Kaitlyn, Bowen, Karin, Colice, Gene, Hetzel, Jorge Lima, Fiterman, Jussara, Souza Machado, Adelmir, Antila, Martti Anton, Lima, Marina Andrade, Minamoto, Suzana Erico Tanni, Blanco, Daniela Cavalet, Bezerra, Patricia Gomes de Matos, Houle, Pierre-Alain, Lemiere, Catherine, Melenka, Lyle S, Leigh, Richard, Mitchell, Patrick, Anees, Syed, Pek, Bonavuth, Chouinard, Guy, Cheema, Amarjit S, Yang, William Ho-Ching, Philteos, George, Chanez, Pascal, Bourdin, Arnaud, Devouassoux, Gilles, Taille, Camille, De Blay, Frédéric, Leroyer, Christophe, Beurnier, Antoine, Garcia, Gilles, Girodet, Pierre-Olivier, Blanc, François-Xavier, Magnan, Antoine, Wanin, Stéphanie, Just, Jocelyne, Linde, Richard, Zielen, Stefan, Förster, Karin, Geßner, Christian, Jandl, Margret, Buhl, Roland Otto, Korn, Stephanie, Kornmann, Marc Oliver, Linnhoff, Anneliese, Ludwig-Sengpiel, Andrea, Ehlers, Martin, Schmoller, Tibor, Steffen, Heiner, Hoffmann, Martin, Kirschner, Joachim, Schmidt, Olaf, Welte, Tobias, Temme, Hilke, Wand, Ori, Bar-Shai, Amir, Izbicki, Gabriel, Berkman, Neville, Fink, Gershon, Shitrit, David, Adir, Yochai, Kuna, Piotr, Rewerska, Barbara, Pisarczyk-Bogacka, Ewa, Kurbacheva, Oksana, Mikhailov, Sergey L, Vasilev, Maksim, Emelyanov, Alexander, Wali, Siraj, Albanna, Amr, van Zyl-Smit, Richard, Abdullah, Ismail, Abdullah, Ismail, Bernhardi, David, Hoosen, Farzana, Irusen, Elvis, Kalla, Ismail, Lakha, Deepak, Mitha, Essack, Naidoo, Visvakuren, Nell, Haylene, Padayachee, Trevenesan, Reddy, Jeevren, Petrick, Friedrich, van der Walt, Eugene, Vawda, Zubar Fazal Ahmed, Park, Hae-Sim, Lee, Sang Haak, Kim, Mi-Kyeong, Park, Jung-Won, Cho, You Sook, Lee, Byung Jae, Chang, Yoon-Seok, Park, Choon-Sik, Lee, Kwan Ho, Lee, Sook Young, Yoon, HyoungKyu, Sohn, Kyoung Hee, Park, Myung Jae, Min, Kyung Hoon, Cho, Young Joo, Park, Han Ki, Lee, YongChul, Lee, Jaechun, Sheu, Chau-Chyun, Tu, Chih-Yen, Lee, Kang-Yun, Bavbek, Sevim, Gemicioglu, Bilun, Ediger, Dane, Kalkan, Ilkay Koca, Makieieva, Nataliia, Ostrovskyy, Mykola, Dytyatkovs'ka, Yevgeniya, Mostovoy, Yuriy Mykhaylovych, Lebed, Kyrylo, Yakovenko, Oleh, Adams, Atoya, Mooring, Timothy, Torres Jr, Louis, Sexton, Marvin, Thompson, Ernest, Bernstein, Jonathan A, Lisi, Paul, Chappel, Christopher M, Cole, Jeremy, Greenwald, Gary I, Jones, Conigliaro, Klein, Ryan Mitchell, Pham, David N, Spangenthal, Selwyn, Weinstein, Steven F, Windom, Hugh H, Kao, Neil L, Leong, Mila A, Mehta, Vinay, Moore, Wendy C, Bhat, Saligrama, Aish, Bassil, Meltzer, Steven M, Corren, Jonathan, Moss, Mark H, Kerwin, Edward M, Delgado, John Palsted, Lucksinger, Gregg Hudson, Thompson, Charles A, Chupp, Geoffrey, Alpizar, Sady A, Vadgama, Sanjay Virgi, Zafar, Zahid, Jacobs, Joshua S, Lugogo, NJira, Jain, Neal, Sher, Lawrence D, Andrawis, Nabil S, Fuentes, David, Boren, Eric Jason, Gonzalez, Erika G, Talreja, Neetu, Durrani, Sheharyar Sandy, Israel, Elliot, Sekhsaria, Sudhir, DeLeon, Samuel, Shukla, Mayank, Totszollosy Tarpay, Martha M, Fakih, Faisal, Hudes, Golda, Tillinghast, Jeffrey P, Korenblat, Phillip E, Shenoy, Kartik, Que, Loretta, Kureishy, Shahrukh Ahmad, Umeh, Fred Chukwuemeka, Nguyen, Vinh Nhu, Chu, Hanh Thi, Nguyen, Thuy Thi Dieu

Publikováno v: The Lancet Respiratory Medicine; May 2023, Vol. 11 Issue: 5 p425-438, 14p

Evaluation of the oral corticosteroid-sparing effect of tezepelumab in adults with oral corticosteroid-dependent asthma (SOURCE): a randomised, placebo-controlled, phase 3 study

Autor: Wechsler, Michael E, Menzies-Gow, Andrew, Brightling, Christopher E, Kuna, Piotr, Korn, Stephanie, Welte, Tobias, Griffiths, Janet M, Sałapa, Kinga, Hellqvist, Åsa, Almqvist, Gun, Lal, Harbans, Kaur, Primal, Skärby, Tor, Colice, Gene, Cambursano, Victor H, Fernandez, Marcelo J, Scherbovsky, Fernando D, Yanez, Anahi, Tolcachier, Alberto J, Stok, Ana M, Verra, Fernando J B, Korn, Stephanie, Forster, Karin, Rolke, Mathias, Ludwig-Sengpiel, Andrea, Schmoller, Tibor, Schmidt, Olaf, Milger-Kneidinger, Katrin, Hoffmann, Martin, Temme, Hilke, Linnhoff, Anneliese, Welte, Tobias, Kirschner, Joachim, Kuna, Piotr, Rewerska, Barbara, Pisarczyk-Bogacka, Ewa, Haak Lee, Sang, Jae Lee, Byung, Park, Heung-Woo, Park, Jung-Won, Young Lee, Sook, Sook Cho, You, Ho Lee, Kwan, Bavbek, Sevim, Gemicioglu, Bilun, Ediger, Dane, Koca Kalkan, Ilkay, Hanta, Ismail, Yorgancioglu, Arzu, DytyatkovsKa, Yevgeniya, Mostovoy, Yuriy M, Lebed, Kyrylo, Yakovenko, Oleh, Bernstein, David I, Tillinghast, Jeffrey P, Que, Loretta, Madison, Jan, Rambasek, Todd, Shenoy, Kartik, Thompson, Charles A, Chappel, Christopher M, Hudes, Golda, Sorial, Ehab, Kureishy, Shahrukh A, Rehman, Syed M, Lugogo, Njira, Gonzalez, Erika G, Umeh, Fred C, Boren, Eric J, Sigmon, Jason, Ismail, Hummayun, Mohan, Arjun, Bansal, Sandeep, Kaelin, Thomas D

Publikováno v: The Lancet Respiratory Medicine; July 2022, Vol. 10 Issue: 7 p650-660, 11p