Malignant teratoid tumor of the thyroid gland: an aggressive primitive multiphenotypic malignancy showing organotypical elements and frequent DICER1 alterations-is the term "thyroblastoma" more appropriate?

Autor: Agaimy A; Institute of Pathology, University Hospital Erlangen, Erlangen, Germany. abbas.agaimy@uk-erlangen.de., Witkowski L; Departments of Human Genetics, McGill University, Montreal, Quebec, Canada., Stoehr R; Institute of Pathology, University Hospital Erlangen, Erlangen, Germany., Cuenca JCC; Instituto de Anatomía Patológica Arias Stella, Lima, Peru., González-Muller CA; Instituto de Anatomía Patológica Arias Stella, Lima, Peru., Brütting A; Department of Surgery, Malteser Waldkrankenhaus, Erlangen, Germany., Bährle M; Department of Surgery, Malteser Waldkrankenhaus, Erlangen, Germany., Mantsopoulos K; Department of Otorhinolaryngology, Head and Neck Surgery, University of Erlangen-Nuremberg, Erlangen, Germany., Amin RMS; Department of Pathology, King Fahad Specialist Hospital, Dammam, Saudi Arabia., Hartmann A; Institute of Pathology, University Hospital Erlangen, Erlangen, Germany., Metzler M; Department of Pediatrics, University Hospital Erlangen, Erlangen, Germany., Amr SS; Department of Pathology, King Fahad Specialist Hospital, Dammam, Saudi Arabia., Foulkes WD; Departments of Human Genetics, McGill University, Montreal, Quebec, Canada.; Cancer Research Program, Research Institute of the McGill University Health Centre, McGill University, Montreal, Quebec, Canada.; Cancer Genetics Laboratory, Lady Davis Institute, Jewish General Hospital, McGill University Montreal, Montreal, Quebec, Canada., Sobrinho-Simões M; Instituto de Investigação e Inovação em Saúde, Porto, Portugal.; Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal.; Medical Faculty, University of Porto, Porto, Portugal.; Department of Pathology, Centro Hospitalar S. João, Porto, Portugal., Eloy C; Instituto de Investigação e Inovação em Saúde, Porto, Portugal.; Institute of Molecular Pathology and Immunology, University of Porto, Porto, Portugal.; Medical Faculty, University of Porto, Porto, Portugal.

Publikováno v: Virchows Archiv : an international journal of pathology [Virchows Arch] 2020 Dec; Vol. 477 (6), pp. 787-798. Date of Electronic Publication: 2020 Jun 07.