Dynamic in vitro culture of cryopreserved-thawed human ovarian cortical tissue using a microfluidics platform does not improve early folliculogenesis

Autor: Julieta S. Del Valle, Vanessa Mancini, Maitane Laverde Garay, Joyce D. Asseler, Xueying Fan, Jeroen Metzemaekers, Leoni A. Louwe, Gonneke S. K. Pilgram, Lucette A. J. van der Westerlaken, Norah M. van Mello, Susana M. Chuva de Sousa Lopes

Publikováno v: Frontiers in Endocrinology, Vol 13 (2022)

Current strategies for fertility preservation include the cryopreservation of embryos, mature oocytes or ovarian cortical tissue for autologous transplantation. However, not all patients that could benefit from fertility preservation can use the curr

Externí odkaz: https://doaj.org/article/7eff3353183d41d5a827d6c5cf0bc0d9

Validation of the blood gas analyzer for pH measurements in IVF culture medium: Prevent suboptimal culture conditions.

Autor: Juan D N Diaz de Pool, Sjoerd A A Van Den Berg, Gonneke S K Pilgram, Bartholomeus E P B Ballieux, Lucia A J Van Der Westerlaken

Publikováno v: PLoS ONE, Vol 13, Iss 11, p e0206707 (2018)

Measurement of pH in IVF-media using the blood gas analyzer (BGA) requires validation, because IVF-media is outside the intended scope of the BGA. To determine whether the Siemens Rapidpoint 500 BGA is suitable for pH measurements in IVF-media this s

Externí odkaz: https://doaj.org/article/b99dcfbede394c8981b53f8f4a8054df

Single-Cell Transcriptomics Analysis of Human Small Antral Follicles

Autor: Susana M. Chuva de Sousa Lopes, Hailiang Mei, Monika Bialecka, Julieta S. del Valle, Arend W. Overeem, Gonneke S. K. Pilgram, Xueying Fan, Ioannis Moustakas, Lucette A. J. van der Westerlaken, Leoni A. Louwe

Publikováno v: International Journal of Molecular Sciences, 22(21). MDPI
International Journal of Molecular Sciences
Volume 22
Issue 21
International Journal of Molecular Sciences, Vol 22, Iss 11955, p 11955 (2021)
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
PLoS Genetics, 22(21). MDPI

Human ovarian folliculogenesis is a highly regulated and complex process. Characterization of follicular cell signatures during this dynamic process is important to understand follicle fate (to grow, become dominant, or undergo atresia). The transcri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b11ab6002913cc10427438574b377e82
http://hdl.handle.net/1887/3278147

Ovarian tissue cryopreservation: low usage rates and high live-birth rate after transplantation

Autor: Ellen J. Hoekman, Cornelis D. de Kroon, Maxime Rooijers, Carina G. J. M. Hilders, Gonneke S. K. Pilgram, Nicole F. Klijn, Lucette A. J. van der Westerlaken, Leoni A. Louwe

Publikováno v: Acta Obstetricia et Gynecologica Scandinavica, 99(2), 213-221. WILEY
Acta Obstetricia et Gynecologica Scandinavica

Introduction The likelihood of survival after cancer treatment among young women with cancer has increased considerably, quality of life after treatment has drawn more attention. However, in young fertile women, fertility preservation is an important

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::defb321409ff6989fed888028cdaaeb3
http://hdl.handle.net/1887/3181498

Two live births following orthotopic ovarian tissue autotransplantation: A case report of cycle monitoring and (modified) natural-cycle IVF in one patient

Autor: Gonneke S. K. Pilgram, Lucia Alida Johanna van der Westerlaken, Leoni A. Louwe, Nicole F. Klijn

Publikováno v: Case Reports in Women's Health, Vol 24, Iss, Pp-(2019)
Case Reports in Women's Health

Highlights • Ovarian tissue cryopreservation is a successful fertility preservation treatment. • Ovarian tissue placed in a peritoneal window leads to reactivation of the tissue. • Cycle monitoring after transplantation is necessary to confirm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9adc80ea4ef16cdd6498f07e71cdd06
http://www.sciencedirect.com/science/article/pii/S2214911219301249