Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Gongqiao Xu"'
Autor:
Sameera Rahman, Rongquan Wang, Sherilyn L. Bell, Ismat A Khatri, Gongqiao Xu, Janet F. Forstner
Publikováno v:
Biochemical Journal. 373:893-900
Within the C-terminal domain of many secretory mucins is a ‘cystine knot’ (CK), which is needed for dimer formation in the endoplasmic reticulum. Previous studies indicate that in addition to an unpaired cysteine, the three intramolecular cystine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::870949367a813166b73d5dc458db8db5
https://doi.org/10.1042/bj20030096
https://doi.org/10.1042/bj20030096
Publikováno v:
Biochemical Journal. 357:203-209
DNA constructs based on the 534-amino-acid C-terminus of rat mucin protein Muc2 (RMC), were transfected into COS cells and the resultant 35S-labelled dimers and monomers were detected by SDS/PAGE of immunoprecipitates. The cystine-knot construct, enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8229188e35a982a8cf1bfb9f741df3db
https://doi.org/10.1042/bj3570203
https://doi.org/10.1042/bj3570203
Publikováno v:
European Journal of Biochemistry. 267:2998-3004
Earlier immunolocalization experiments showed that the extreme cationic C-terminus of the rat intestinal mucin Muc2 (RMC) was present at the base of intestinal goblet cells in the vicinity of ER and golgi compartments, but was not found with the rest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2580d1f4775a488ba56e0dbf82ddc25
https://doi.org/10.1046/j.1432-1033.2000.01319.x
https://doi.org/10.1046/j.1432-1033.2000.01319.x
Publikováno v:
Biochemical Journal. 286:335-338
Expression of the gene for a rat intestinal mucin-like peptide (MLP) was studied by Northern-blot analyses of RNA prepared from a panel of rat tissues. Four probes (A-D) were constructed so as to span a 3.5 kb-long cDNA for rat MLP, and used for hybr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5a0e3c77451bc9fe21b2fd936b70fcd
https://doi.org/10.1042/bj2860335
https://doi.org/10.1042/bj2860335
Autor:
I. A. Khatri, Gordon G. Forstner, D. Wang, Ling-Jung Huan, A. Bennick, Janet F. Forstner, R E F Fahim, Gongqiao Xu
Publikováno v:
Journal of Biological Chemistry. 267:5401-5407
When subjected to thiol reduction, purified intestinal mucins have been shown to undergo a decrease in molecular mass and to liberate a 118-kDa glycopeptide (Roberton, A. M., Mantle, M., Fahim, R. E. F., Specian, R., Bennick, A., Kawagishi, S., Sherm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1cf140b758ca0cfd2f347091f42d7786
https://doi.org/10.1016/s0021-9258(18)42780-9
https://doi.org/10.1016/s0021-9258(18)42780-9
Publikováno v:
European journal of biochemistry. 253(1)
We have investigated the possibility that the intestinal mucin rat Muc2 forms dimers during biosynthesis via intermolecular disulphide bridging of its C-terminal domains. Since the cysteine alignment of RMuc2 (and other secretory mucins) is similar t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c6052e3e64946e243147b8c9fcf5e6
https://pubmed.ncbi.nlm.nih.gov/9578469
https://pubmed.ncbi.nlm.nih.gov/9578469
Publikováno v:
Glycoconjugate journal. 13(1)
Unlike most other mucins described to date, two intestinal mucins, rat MLP (rat Muc 2) and human MUC2 have a C-terminal tail that is enriched in cationic amino acids. The distribution of charge in each case resembles that of several well known hepari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ec0a486cb7f66acb53aa11a1c6d0a55
https://pubmed.ncbi.nlm.nih.gov/8785492
https://pubmed.ncbi.nlm.nih.gov/8785492