Zobrazeno 1 - 10 of 204 pro vyhledávání: '"Gonghua Song"'
1
An Effective Strategy to Develop Potent and Selective Antifungal Agents from Cell Penetrating Peptides in Tackling Drug-Resistant Invasive Fungal Infections
Autor: Yueming Wu, Weinan Jiang, Zihao Cong, Kang Chen, Yunrui She, Chao Zhong, Wenjing Zhang, Minzhang Chen, Min Zhou, Ning Shao, Guohui Xiao, Xiaoyan Shao, Yidong Dai, Jian Fei, Gonghua Song, Runhui Liu
Publikováno v: Journal of Medicinal Chemistry. 65:7296-7311
The high mortality rate of invasive fungal infections and quick emergence of drug-resistant fungal pathogens urgently call for potent antifungal agents. Inspired by the cell penetrating peptide (CPP) octaarginine (R8), we elongated to 28 residues pol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c663dc2a495c743bb3d98d4354a8e9c4
https://doi.org/10.1021/acs.jmedchem.2c00274
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2
Copper-Catalyzed Three-Component Reactions of α-Ketoaldehyde, 1,3-Dicarbonyl Compound, and Organic Boronic Acid in Water: A Route to 1,4-Diketones
Autor: Yanqing Peng, Yaxuan Zhou, Jiayi Wang, Qi Xia, Fu Xi, Gonghua Song, Xiang Li
Publikováno v: The Journal of Organic Chemistry. 86:9914-9923
A novel three-component reaction of α-ketoaldehydes, 1,3-dicarbonyl compounds, and organic boronic acids catalyzed by CuO in water has been developed to give a wide range of products containing 1,3/1,4-diketones. The method has some advantages such
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e296e07a8e27813673e2bfc4fe18582
https://doi.org/10.1021/acs.joc.1c01100
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3
Advance and Designing Strategies in Polymeric Antifungal Agents Inspired by Membrane-Active Peptides
Autor: Weinan Jiang, Yueming Wu, Min Zhou, Gonghua Song, Runhui Liu
Publikováno v: Chemistry (Weinheim an der Bergstrasse, Germany). 28(65)
The high-mortality invasive fungal infections seriously threaten the lives of immunocompromised people. Host defense peptides and cell-penetrating peptides are representative membrane-active peptides with different functions. Among them, host defense
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61df0b9c9870de3e82d39639aa521b20
https://pubmed.ncbi.nlm.nih.gov/35996361
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6
Multistep Synthesis and Nematicidal Activity of 2-(8-azabicyclo[3.2.1]octan-3-yl)-3-imino-2,3-dihydro-1H-isoindol-1-One Derivatives
Autor: Jiayi Wang, Gonghua Song, Tianjiao Yang, Jun Xu
Publikováno v: Chemistry of Heterocyclic Compounds. 57:31-39
Novel 2-(8-azabicyclo[3.2.1]octan-3-yl)-3-imino-2,3-dihydro-1H-isoindol-1-ones derived from 5-HT3 receptor antagonists hexahydroazepinylbenzamides were designed and synthesized through isocyanide insertion reaction. All target compounds were evaluate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::572d49f2d2b3e59780d7ab08ba7d3a8b
https://doi.org/10.1007/s10593-021-02864-z
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7
Development and application of a microwave loop reactor radiating through a leaky coaxial antenna(s)
Autor: Yanqing Peng, Shengjie Lin, Jiayi Wang, Gonghua Song, Yu Li
Publikováno v: New Journal of Chemistry. 45:14650-14654
A novel microwave (MW) loop reactor radiating through a leaky coaxial antenna(s) was developed in this study. Compared with the traditional airlift loop reactor, this loop reactor can perform effective circulation due to MW-induced evaporation and wi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f58f38b324b91b4837d557a22f6948e5
https://doi.org/10.1039/d1nj01668g
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8
Regioselective and diastereodivergent organocatalytic asymmetric vinylogous Michael addition
Autor: Yanxiong Ke, Chuncheng Zou, Jinxing Ye, Yanting Lv, Lei Zhang, Gonghua Song, Min Lu, Lei Yang, Zhen Liu, Xin Li
Publikováno v: Organic Chemistry Frontiers. 8:4758-4766
Regioselective and diastereodivergent asymmetric vinylogous Michael addition (AVMA) between β-substituted-cyclohexenones and nitroalkenes via dienamine activation under complementary chiral aminocatalysts was reported. γ-Regioselective AVMA of β-a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7fcc211ece22c22917c96a820ea3f10b
https://doi.org/10.1039/d1qo00371b
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9
[Development of a first-class undergraduate major in bioengineering facing the emerging engineering direction of biomedicine]
Autor: Qiyao, Wang, Shuhong, Gao, Yunpeng, Bai, Guobin, Ren, Yingping, Zhuang, Gonghua, Song
Publikováno v: Sheng wu gong cheng xue bao = Chinese journal of biotechnology. 38(3)
In the "Tutorial for outline of the healthy China 2030 plan", biomedicine was listed as a key planning and development area. Shanghai government also lists biomedicine as an emerging pillar industry. The rapid development of biomedicine industry put
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::44bdd767b4a3c1e93aef6021905238d8
https://pubmed.ncbi.nlm.nih.gov/35355488
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10
Along‐strike structural linkage and interaction in an active thrust fault system: A case study from the western Sichuan foreland basin, China
Autor: Maomao Wang, Wang Feng, Gonghua Song, Zhuxin Chen, Danqi Jiang, Bing Yan
Publikováno v: Basin Research. 33:210-226
[This article describes structural linkage and interactions patterns in an active thrust system in the western Sichuan foreland basin. Lateral growth and linkage of thrust fault segments restrict fault development, generate a defict between structura
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3977e7881b74b4b8b892746af4df37c9
https://doi.org/10.1111/bre.12461
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