Zobrazeno 1 - 10 of 41 pro vyhledávání: '"Gongda Xue"'
1
Akademický článek
Artificial 64-Residue HIV-1 Enhancer-Binding Peptide Is a Potent Inhibitor of Viral Replication in HIV-1-Infected Cells
Autor: Mouhssin Oufir, Leslie R. Bisset, Stefan R. K. Hoffmann, Gongda Xue, Stephan Klauser, Bianca Bergamaschi, Alain Gervaix, Jürg Böni, Jörg Schüpbach, Bernd Gutte
Publikováno v: Advances in Virology, Vol 2011 (2011)
An artificial HIV-1 enhancer-binding peptide was extended by nine consecutive arginine residues at the C-terminus and by the nuclear localization signal of SV40 large T antigen at the N-terminus. The resulting synthetic 64-residue peptide was found t
Externí odkaz: https://doaj.org/article/92fc98ba0c004ad3bd069b5d19189400
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2
Akademický článek
The transforming parasite Theileria co-opts host cell mitotic and central spindles to persist in continuously dividing cells.
Autor: Conrad von Schubert, Gongda Xue, Jacqueline Schmuckli-Maurer, Kerry L Woods, Erich A Nigg, Dirk A E Dobbelaere
Publikováno v: PLoS Biology, Vol 8, Iss 9 (2010)
The protozoan parasite Theileria inhabits the host cell cytoplasm and possesses the unique capacity to transform the cells it infects, inducing continuous proliferation and protection against apoptosis. The transforming schizont is a multinucleated s
Externí odkaz: https://doaj.org/article/493d671be2bd47a4b4b0b95135c4da59
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7
Data from hMOB3 Modulates MST1 Apoptotic Signaling and Supports Tumor Growth in Glioblastoma Multiforme
Autor: Debora Schmitz-Rohmer, Brian A. Hemmings, Stephan Frank, Alexander Hergovich, Christian Hundsrucker, Peter D. Cron, Yuhua Wang, Debby Hynx, Gongda Xue, Lei Zhang, Fengyuan Tang
New therapeutic targets are needed that circumvent inherent therapeutic resistance of glioblastoma multiforme (GBM). Here, we report such a candidate target in the uncharacterized adaptor protein hMOB3, which we show is upregulated in GBM. In a searc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6b6b33904a163ab0e191517dc0edd9
https://doi.org/10.1158/0008-5472.c.6506568.v1
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9
PKB/Akt-Dependent Regulation of Cell Motility
Autor: Gongda Xue, Brian A. Hemmings
Publikováno v: J Natl Cancer Inst.
The prosurvival activity of phosphoinositide 3 kinase (PI3K)/Akt (also known as protein kinase B, PKB) pathway has been investigated in great detail in human physiology and disease. Accumulating evidence is emerging that this signaling axis also acti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e622288f289b17d66212d41175484334
http://doc.rero.ch/record/292074/files/djs648.pdf
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10
PKB/Akt-dependent regulation of inflammation in cancer
Autor: Brian A. Hemmings, Fengyuan Tang, Curzio Rüegg, Gongda Xue, Yuhua Wang
Chronic inflammation is a major cause of human cancer. Clinical cancer therapies against inflammatory risk factors are strategically determined. To rationally guide a novel drug development, an improved mechanistic understanding on the pathological c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb33794c20a106e37b0e4e989250a5d0
http://doc.rero.ch/record/288976/files/rue_pdr.pdf
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