Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Gongcheng, Lu"'
Publikováno v:
Pharmaceutical Research. 33:879-892
Therapeutic proteins have become an integral part of health care. However, their controlled delivery remains a challenge. Protein function depends on a delicate three dimensional structure, which can be damaged during the fabrication of controlled re
Publikováno v:
2017 Seventh International Conference on Information Science and Technology (ICIST).
Understanding close-proximity contacts is vitally important to the studies of transmission of respiratory infectious diseases among humans. A variety of researches have been conducted to collect close-proximity contacts in real life among human, espe
Autor:
Liduan Zheng, Liang Wang, Fuqing Zeng, Gongcheng Lu, Ji-Hua Dong, Qiangsong Tong, Fang-Min Chen
Publikováno v:
Cancer Gene Therapy. 12:509-514
X-linked inhibitor of apoptosis (XIAP) is the most potent member of the inhibitor of apoptosis protein (IAP) gene family in terms of its ability to inhibit caspases and suppress apoptosis. Recent evidence has suggested that XIAP is a key determinant
Publikováno v:
2014 40th Annual Northeast Bioengineering Conference (NEBEC).
Protein therapeutics are playing an ever increasing role in disease treatment; however, their controlled release remains challenging. In this study a series of microgels with varying crosslinking densities was synthesized, characterized and evaluated
Autor:
Shian Xing, Xiao Liang, Gongcheng Lu, Chen Lin, Ming Fu, Ming Wu, Fuqing Zeng, Zhaohui Zhu, Xue-yan Zhang
Publikováno v:
Journal of Huazhong University of Science and Technology [Medical Sciences]. 22:324-326
To evaluate the effects of adenovirus (Ad)-mediated transfer of p53 and p16 on human bladder cancer cells EJ, EJ were transfected with Ad-p53 and Ad-p16. Cell growth, morphological change, cell cycle, apoptosis were measured using MTT assay, flow cyt
Publikováno v:
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. 26(5)
The killing effects of herpes simplex virus thymidine kinase gene/ganciclovir (HSV-tk/GCV) approach by the addition of several commonly clinical chemotherapeutic agents on hormone refractory prostate cancer (HRPC) cells PC-3m were investigated. After
Publikováno v:
Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. 25(6)
The serine protease Omi/HtrA2 is released from mitochondria into the cytosol after apoptotic stimuli, inducing apoptosis in a caspase-independent manner through its protease activity and in a caspase-dependent manner by neutralizing the inhibition of
Publikováno v:
The Chinese-German Journal of Clinical Oncology. 3
To correlate the frequency of p53 mutations, bcl-2 expression and the proliferation status (proliferating cell nuclear antigen, PCNA) in patients with bladder cancer with cell proliferation, apoptosis and their clinico-pathologic findings. Paraffin-e
Autor:
Zhaohui, Zhu, Shian, Xing, Chen, Lin, Xueyan, Zhang, Ming, Fu, Xiao, Liang, Fuqing, Zeng, Gongcheng, Lu, Min, Wu
Publikováno v:
Chinese medical journal. 116(12)
To evaluate the antitumor efficacy of proliferating cell nuclear antigen antisense oligonucleotide (PCNA-ASO) in combination with recombinant adenovirus p53 (Ad-p53) against bladder cancer EJ and BIU-87 cells in vitro and in vivo.Cells were transfect
Publikováno v:
Chinese medical journal. 116(10)
To study the possibility of gene therapy for prostate cancer by blocking androgen receptor (AR) gene expression using a specific hammerhead ribozyme (RZ).The hammerhead ribozyme expression vector pcDNA-hAR-RZ, specific to AR mRNA, was constructed and