Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Gongchang, Yu"'
Autor:
Shuangshuang Pu, Zhifeng Yang, Xiaofeng Zhang, Ming Li, Na Han, Xiaohan Yang, Jin He, Gongchang Yu, Xiangjing Meng, Qiang Jia, Hua Shao
Publikováno v:
Chinese Medicine, Vol 18, Iss 1, Pp 1-16 (2023)
Abstract Background Silicosis is an important occupational disease caused by inhalation of free silica and is characterized by persistent pulmonary inflammation, subsequent fibrosis and lung dysfunction. Until now, there has been no effective treatme
Externí odkaz:
https://doaj.org/article/73849d224431412ca167a6a4c7fc0643
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e22920- (2023)
As the body's first line of defense, neutrophils play an important role in the early stages of infection. Neutrophil extracellular traps (NETs), a novel way to kill pathogens, are released from activated neutrophils to trap and kill microorganisms an
Externí odkaz:
https://doaj.org/article/572d9cb97dbf40ae849b23af2fc402e9
Autor:
Shengchang Zhang, Ying Liu, Weiqiang Jing, Qihao Chai, Chunwei Tang, Ziyang Li, Zhentao Man, Chen Chen, Jing Zhang, Peng Sun, Rui Zhang, Zhenmei Yang, Maosen Han, Yan Wang, Xia Wei, Jun Li, Wei Li, Mohnad Abdalla, Gongchang Yu, Bin Shi, Yuankai Zhang, Kun Zhao, Xinyi Jiang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Proinflammatory macrophages are involved in rheumatoid arthritis (RA). Here the authors use an efferocytosis-mimetic self-deliverable nanoimitator to mitigate RA by targeted reprogramming of synovial inflammatory macrophages, reducing proinflammatory
Externí odkaz:
https://doaj.org/article/3616fe9a018e4bd2b78df3db34eee873
Autor:
Meng Yin, Wenchang Xu, Jixiang Pang, Siwen Xie, Mengting Xiang, Bin Shi, Hua Fan, Gongchang Yu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundOsteoarthritis (OA) is a degenerative disease with high prevalence. Some observational studies have shown that patients with osteoarthritis often have co-existing cardiovascular diseases (CVD) such as atrial fibrillation (AF) and coronary a
Externí odkaz:
https://doaj.org/article/4c61211d620149a6863c19c953ac5218
Autor:
Cunxiang Bo, Juan Zhang, Linlin Sai, Zhongjun Du, Gongchang Yu, Chao Li, Ming Li, Cheng Peng, Qiang Jia, Hua Shao
Publikováno v:
BMC Pulmonary Medicine, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Silicosis is a systemic disease characterized by persistent inflammation and incurable pulmonary fibrosis. Although great effort has been made to understand the pathogenesis of the disease, molecular mechanism underlying silicosis
Externí odkaz:
https://doaj.org/article/e46e1cbaebb648bba7e4128a5a93c630
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Observational data from China, the United States, France, and Italy suggest that chronological age is an adverse COVID-19 outcome risk factor, with older patients having a higher severity and mortality rate than younger patients. Most studies have go
Externí odkaz:
https://doaj.org/article/b5e6f5500ebe4005b9041f57a9f89a7b
Publikováno v:
Genes and Environment, Vol 43, Iss 1, Pp 1-12 (2021)
Abstract Background Exposure to respirable crystalline silica (RCS) can induce accelerated silicosis (AS), a form of silicosis that is more progressive and severe form of silicosis. In this project we aimed to assess processes of silicosis in rats ex
Externí odkaz:
https://doaj.org/article/ef0920bc53bc47e89aecb8b41992ef7c
Autor:
Xiaoshu Chen, Xinru Pang, Abrey J. Yeo, Siwen Xie, Mengting Xiang, Bin Shi, Gongchang Yu, Chao Li
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
The blood-brain barrier (BBB) is a selective, semi-permeable layer of endothelial cells that protects the central nervous system from harmful substances circulating in blood. It is one of the important barriers of the nervous system. BBB dysfunction
Externí odkaz:
https://doaj.org/article/4bdc0dd7882d4c89b87cc20a513566f7
Autor:
Cunxiang Bo, Xiao Geng, Juan Zhang, Linlin Sai, Yu Zhang, Gongchang Yu, Zhenling Zhang, Kai Liu, Zhongjun Du, Cheng Peng, Qiang Jia, Hua Shao
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0241310 (2020)
Silicosis is a systemic disease characterized by chronic persistent inflammation and incurable pulmonary fibrosis with the underlying molecular mechanisms to be fully elucidated. In this study, we employed tandem mass tag (TMT) based on quantitative
Externí odkaz:
https://doaj.org/article/1afb6dc52d884512bdc5ad56206b4cfc
Autor:
Ziyang Li, Shengchang Zhang, Zhipeng Fu, Ying Liu, Zhentao Man, Chongdeng Shi, Chunwei Tang, Chen Chen, Qihao Chai, Zhenmei Yang, Jing Zhang, Xiaotian Zhao, Hailun Xu, Maosen Han, Yan Wang, Ziyang Liao, Gongchang Yu, Bin Shi, Kun Zhao, Wei Li, Xinyi Jiang
Publikováno v:
Science Advances. 9
Tracking and eradicating Staphylococcus aureus in the periprosthetic microenvironment are critical for preventing periprosthetic joint infection (PJI), yet effective strategies remain elusive. Here, we report an implant nanoparticle coating that loco