Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Gong Rak Lee"'
Autor:
Han Saem Son, Jiae Lee, Hye In Lee, Narae Kim, You-Jin Jo, Gong-Rak Lee, Seong-Eun Hong, Minjeong Kwon, Nam Young Kim, Hyun Jin Kim, Jin Ha Park, Soo Young Lee, Woojin Jeong
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 3, Pp 462-474 (2020)
Bone diseases such as osteoporosis and periodontitis are induced by excessive osteoclastic activity, which is closely associated with inflammation. Benzydamine (BA) has been used as a cytokine-suppressive or non-steroidal anti-inflammatory drug that
Externí odkaz:
https://doaj.org/article/2c2b74b3caee435aaae03777f6052a77
Autor:
Nam Young Kim, Minjeong Kwon, Ye Hee Kang, Hyeong Ju Song, Narae Kim, Woojin Jeong, Hyun Jin Kim, Dong Min Shin, Hye In Lee, Jin Ha Park, Gong Rak Lee, Jiae Lee, TaeSoo Kim
Publikováno v:
Journal of Cellular Physiology. 236:8239-8252
Many bone diseases such as osteoporosis and periodontitis are caused by hyperactivation of osteoclasts. Calcium (Ca2+ ) signals are crucial for osteoclast differentiation and function. Thus, the blockade of Ca2+ signaling may be a strategy for regula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5c880d494e5e0ae3ffc742a63390566
https://doi.org/10.1002/jcp.30496
https://doi.org/10.1002/jcp.30496
Autor:
Gong‐Rak Lee, Hye In Lee, Narae Kim, Jiae Lee, Minjeong Kwon, Ye Hee Kang, Hyeong Ju Song, Chang‐Yeol Yeo, Woojin Jeong
Publikováno v:
Journal of cellular physiologyREFERENCES. 237(9)
Nonalcoholic steatohepatitis (NASH) is a liver disease characterized by fat accumulation and chronic inflammation in the liver. Dynein light chain of 8 kDa (LC8) was identified previously as an inhibitor of nuclear factor kappa B (NF-κB), a key regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f380602d286affeef57a5eaa7d673ea
https://pubmed.ncbi.nlm.nih.gov/35696549
https://pubmed.ncbi.nlm.nih.gov/35696549
Autor:
Ye Hee Kang, Narae Kim, Hye In Lee, Gong-Rak Lee, Hyeong Ju Song, Minjeong Kwon, Chang-Yeol Yeo, Woojin Jeong, Jiae Lee
Nonalcoholic steatohepatitis (NASH) is a liver disease characterized by fat accumulation and chronic inflammation in the liver. Although dynein light chain of 8 kDa (LC8) was identified previously as an inhibitor of nuclear factor kappa B (NF-κB), a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f512c179a99152efa31059c84add5685
https://doi.org/10.21203/rs.3.rs-906706/v1
https://doi.org/10.21203/rs.3.rs-906706/v1
Autor:
Hana Lee, Hye In Lee, Hansung Kim, Donghyun Hwang, Dongmin Kang, Eun Kyoung Seo, Minjeong Kwon, Jiae Lee, Woojin Jeong, Narae Kim, Nam Young Kim, Donglan Piao, Hyun Jin Kim, Gong Rak Lee
Publikováno v:
The FASEB Journal. 33:9685-9694
Excessive osteoclast activity can lead to an imbalance between the synthesis and breakdown of bone, with pathologic consequences that include osteoporosis and periodontitis. Thus, controlling osteoclast differentiation and function has significant th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::522aef53ec3d5f757f15fda0b0dd42fe
https://doi.org/10.1096/fj.201900862r
https://doi.org/10.1096/fj.201900862r
Cinchonine inhibits osteoclast differentiation by regulating TAK1 and AKT, and promotes osteogenesis
Autor:
Jin Ha Park, Hyun Jin Kim, Narae Kim, Woojin Jeong, Hye In Lee, Seong-Eun Hong, Hana Lee, Nam Young Kim, Gong-Rak Lee, Han Sung Kim, Minjeong Kwon, You-Jin Jo, Soo Young Lee, Donghyun Hwang, Ye Hee Kang, Jiae Lee
Publikováno v:
Journal of cellular physiologyREFERENCES. 236(3)
Cinchonine (CN) has been known to exert antimalarial, antiplatelet, and antiobesity effects. It was also recently reported to inhibit transforming growth factor β-activated kinase 1 (TAK1) and protein kinase B (AKT) through binding to tumor necrosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc96e96acd4c22f4ad3de76ee617417e
https://pubmed.ncbi.nlm.nih.gov/32700766
https://pubmed.ncbi.nlm.nih.gov/32700766
Autor:
Narae Kim, Minjeong Kwon, Hye In Lee, Gong-Rak Lee, Jiae Lee, You-Jin Jo, Han Saem Son, Woojin Jeong, Nam Young Kim, Hyun Jin Kim, Seong-Eun Hong, Yoojin Lee, Eun Kyoung Seo
Publikováno v:
The FASEB Journal. 33:2026-2036
Many bone diseases, such as osteoporosis and rheumatoid arthritis, are attributed to an increase in osteoclast number or activity; therefore, control of osteoclasts has significant clinical implications. This study shows how skullcapflavone II (SFII)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ac95d19c4019afe2ed6427d7e6654f2
https://doi.org/10.1096/fj.201800866rr
https://doi.org/10.1096/fj.201800866rr
Autor:
Narae Kim, Dong Hyun Seo, Hansem Shon, Woojin Jeong, Hye In Lee, Seong Eun Hong, Hansung Kim, Jiae Lee, You Jin Jo, Minjung Kwon, Doo Ri Park, Gong Rak Lee, Soo Young Lee, Eun Kyoung Seo
Publikováno v:
Free Radical Biology and Medicine. 112:191-199
Excessive bone resorption caused by increased osteoclast number or activity leads to a variety of bone diseases including osteoporosis, rheumatoid arthritis and periodontitis. Thus, the therapeutic strategy for these diseases has been focused primari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d5df9744516fb173401b2af2439f019
https://doi.org/10.1016/j.freeradbiomed.2017.07.030
https://doi.org/10.1016/j.freeradbiomed.2017.07.030
Autor:
Nam Young Kim, Hye In Lee, Jin Ha Park, Minjeong Kwon, Hyun Jin Kim, Narae Kim, Jiae Lee, Woojin Jeong, Gong Rak Lee
Publikováno v:
BMB Reports
Excessive and hyperactive osteoclast activity causes bone diseases such as osteoporosis and periodontitis. Thus, the regulation of osteoclast differentiation has clinical implications. We recently reported that dehydrocostus lactone (DL) inhibits ost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b85e745f7c54432e6c37c0feb7233bd7
https://pubmed.ncbi.nlm.nih.gov/31964469
https://pubmed.ncbi.nlm.nih.gov/31964469
Autor:
Sue Goo Rhee, Hwan Mook Kim, Gong Rak Lee, Ju Seog Lee, Hye In Lee, Jiae Lee, Woojin Jeong, Tong Shin Chang, Song Kyu Park, Hojin Kim, Hwa Jeong Lee, Sunghoon Kim, You Jin Jo, Jiwon Kim, Jin Young Baek, Seong Eun Hong
Publikováno v:
Free Radical Biology and Medicine. 91:264-274
Recent studies have shown that many types of cancer cells have increased levels of reactive oxygen species (ROS) and enhance antioxidant capacity as an adaptation to intrinsic oxidative stress, suggesting that cancer cells are more vulnerable to oxid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe5b079e5a6f703860b0c8b0c55ddff
https://doi.org/10.1016/j.freeradbiomed.2015.12.023
https://doi.org/10.1016/j.freeradbiomed.2015.12.023