Zobrazeno 1 - 10
of 117
pro vyhledávání: '"Gong Ping, Liu"'
Autor:
Hui-Yang Lei, Gui-Lin Pi, Ting He, Rui Xiong, Jing-Ru Lv, Jia-Le Liu, Dong-Qin Wu, Meng-Zhu Li, Kun Shi, Shi-Hong Li, Na-Na Yu, Yang Gao, Hui-Ling Yu, Lin-Yu Wei, Xin Wang, Qiu-Zhi Zhou, Pei-Lin Zou, Jia-Yang Zhou, Ying-Zhou Liu, Nai-Ting Shen, Jie Yang, Dan Ke, Qun Wang, Gong-Ping Liu, Xi-Fei Yang, Jian-Zhi Wang, Ying Yang
Publikováno v:
Military Medical Research, Vol 11, Iss 1, Pp 1-24 (2024)
Abstract Background Episodic memory loss is a prominent clinical manifestation of Alzheimer’s disease (AD), which is closely related to tau pathology and hippocampal impairment. Due to the heterogeneity of brain neurons, the specific roles of diffe
Externí odkaz:
https://doaj.org/article/df673dbc95c04f9d9dc2c62b7ff993ba
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 7, Pp 1489-1498 (2024)
Alzheimer’s disease is the most prevalent neurodegenerative disease affecting older adults. Primary features of Alzheimer’s disease include extracellular aggregation of amyloid-β plaques and the accumulation of neurofibrillary tangles, formed by
Externí odkaz:
https://doaj.org/article/51fe74dfcc27414db5d0886d6638cd6c
Autor:
Gong-Ping Liu, Shuo Wang
Publikováno v:
Frontiers in Aging Neuroscience, Vol 15 (2023)
Externí odkaz:
https://doaj.org/article/4ec9ac2e76d04a19ae72df5825cbcc59
Autor:
Chongyang Chen, Jing Wang, Donghui Pan, Xinyu Wang, Yuping Xu, Junjie Yan, Lizhen Wang, Xifei Yang, Min Yang, Gong‐Ping Liu
Publikováno v:
MedComm, Vol 4, Iss 4, Pp n/a-n/a (2023)
Abstract Multi‐omics usually refers to the crossover application of multiple high‐throughput screening technologies represented by genomics, transcriptomics, single‐cell transcriptomics, proteomics and metabolomics, spatial transcriptomics, and
Externí odkaz:
https://doaj.org/article/7f5639a60f9a42cfb20b4eff5700f3d1
Autor:
Chongyang Chen, Jing Wang, Chao Yang, Haitao Yu, Bingge Zhang, Xiao Yang, Bocheng Xiong, Yongmei Xie, Shupeng Li, Zaijun Zhang, Feiqi Zhu, Jianjun Liu, Gong‐Ping Liu, Xifei Yang
Publikováno v:
MedComm, Vol 4, Iss 3, Pp n/a-n/a (2023)
Abstract Sleep insufficiency is associated with various disorders; the molecular basis is unknown until now. Here, 14 males and 18 females were subjected to short‐term (24 h) sleep deprivation, and donated fasting blood samples prior to (day 1) and
Externí odkaz:
https://doaj.org/article/c1e9cd426ecf4061877324d3f5fa0c82
Autor:
Qian Liu, Xin Wang, Yu Hu, Jun-Ning Zhao, Chun-Hui Huang, Ting Li, Bing-Ge Zhang, Ye He, Yan-Qing Wu, Zai-Jun Zhang, Guo-Ping Wang, Gong-Ping Liu
Publikováno v:
Redox Biology, Vol 62, Iss , Pp 102697- (2023)
Increased tau acetylation at K274 and K281 has been observed in the brains of Alzheimer's disease (AD) patients and animal models, and mitochondrial dysfunction are noticeable and early features of AD. However, the effect of acetylated tau on mitocho
Externí odkaz:
https://doaj.org/article/94a8882b6abf4fe0a6a1b6442f7ed766
Autor:
Hua-Li Wan, Bing-Ge Zhang, Chongyang Chen, Qian Liu, Ting Li, Ye He, Yongmei Xie, Xifei Yang, Jian-Zhi Wang, Gong-Ping Liu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/52d74e3d99974e449609da71fdf95cd8
Autor:
Xiu Chen, Juan-Ling He, Xue-Ting Liu, Na Zhao, Fan Geng, Meng-Meng Zhu, Gong-Ping Liu, Qing-Guo Ren
Publikováno v:
Neurobiology of Stress, Vol 20, Iss , Pp 100486- (2022)
Our previous study has demonstrated that chronic stress could cause cognitive deficits and tau pathology. However, the underlying mechanism and whether/how DI-3-n-Butylphthalide (NBP) ameliorates these effects are still unclear. Here, Wild-type mice
Externí odkaz:
https://doaj.org/article/c3506f40f2c54a6fa665112cab7fb1dc
Autor:
Xiao-Yue Hong, Hua-Li Wan, Ting Li, Bing-Ge Zhang, Xiao-Guang Li, Xin Wang, Xiao Li, Qian Liu, Chong-Yang Chen, Ying Yang, Qun Wang, Shu-Peng Li, Hao Yu, Jian-Zhi Wang, Xi-Fei Yang, Gong-Ping Liu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-13 (2020)
Abstract In tauopathies, memory impairment positively strongly correlates with the amount of abnormal tau aggregates; however, how tau accumulation induces synapse impairment is unclear. Recently, we found that human tau accumulation activated Signal
Externí odkaz:
https://doaj.org/article/ad0f6d89ab1645c2844726a407241b48
Autor:
Qiuzhi Zhou, Shihong Li, Mengzhu Li, Dan Ke, Qun Wang, Ying Yang, Gong-Ping Liu, Xiao-Chuan Wang, Enjie Liu, Jian-Zhi Wang
Publikováno v:
EBioMedicine, Vol 78, Iss , Pp 103970- (2022)
Summary: Background: Glycogen synthase kinase-3β (GSK-3β) is one of the most effective kinases in promoting tau hyperphosphorylation and accumulation in Alzheimer's disease (AD). However, it is not clear how GSK-3β activity is regulated during AD
Externí odkaz:
https://doaj.org/article/0fcca3d785c44d73ac4603d2974662b7