Mapping low-affinity/high-specificity peptide-protein interactions using ligand-footprinting mass spectrometry.

Autor: Parker BW; Department of Molecular Biosciences, Northwestern University, Evanston, IL 60208., Goncz EJ; Department of Molecular Biosciences, Northwestern University, Evanston, IL 60208., Krist DT; Chemistry of Life Processes Institute, Department of Chemistry, Northwestern University, Evanston, IL 60208., Statsyuk AV; Chemistry of Life Processes Institute, Department of Chemistry, Northwestern University, Evanston, IL 60208.; Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, TX 77204., Nesvizhskii AI; Department of Pathology, University of Michigan, Ann Arbor, MI 48109.; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109., Weiss EL; Department of Molecular Biosciences, Northwestern University, Evanston, IL 60208; elweiss@northwestern.edu.

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Oct 15; Vol. 116 (42), pp. 21001-21011. Date of Electronic Publication: 2019 Oct 02.