Overactive WASp in X-linked neutropenia leads to aberrant B-cell division and accelerated plasma cell generation.

Autor: He M; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden. Electronic address: Minghui.He@ki.se., Saeed MB; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Record J; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Keszei M; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Gonçalves Pinho L; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden; Laboratory on Thymus Research, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil., Vasconcelos-Fontes L; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden; Laboratory on Thymus Research, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil., D'Aulerio R; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Vieira R; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Oliveira MMS; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Geyer C; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Bohaumilitzky L; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Thiemann M; Department of Microbiology Tumor and Cell Biology, Karolinska Institutet, Stockholm, Sweden., Deordieva E; Department of Immunology, Dmitry Rogachev National Medical and Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia., Buedts L; Center for Human Genetics, University Hospital Leuven, Leuven, Belgium., Matias Lopes JP; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY; Division of Allergy, Immunology and Rheumatology, Department of Pediatrics, UH Rainbow Babies and Children's Hospital, Cleveland, Ohio., Pershin D; Department of Immunology, Dmitry Rogachev National Medical and Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia., Hammarström L; Department of Laboratory Medicine, Karolinska Institutet, Stockholm, Sweden., Xia Y; Department of Rheumatology and Immunology, Shenzhen Children's Hospital, Shenzhen, China., Zhao X; Chongqing Key Laboratory of Child Infection and Immunity, Children's Hospital of Chongqing Medical University, Chongqing, China., Cunningham-Rundles C; Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York, NY., Thrasher AJ; UCL Great Ormond Street Institute of Child Health, London, United Kingdom; Great Ormond Street Hospital for Children NHS Foundation Trust, London, United Kingdom., Burns SO; Department of Immunology, Royal Free London NHS Foundation Trust, London, United Kingdom; Institute of Immunity and Transplantation, University College London, London, United Kingdom., Cotta-de-Almeida V; Laboratory on Thymus Research, Oswaldo Cruz Institute, Fiocruz, Rio de Janeiro, Brazil., Liu C; Department of Pathogen Biology, School of Basic Medicine, Huazhong University of Science and Technology, Wuhan, China., Shcherbina A; Department of Immunology, Dmitry Rogachev National Medical and Research Center of Pediatric Hematology, Oncology and Immunology, Moscow, Russia., Vandenberghe P; Center for Human Genetics, University Hospital Leuven, Leuven, Belgium., Westerberg LS; Department of Immunology, Royal Free London NHS Foundation Trust, London, United Kingdom. Electronic address: Lisa.Westerberg@ki.se.

Publikováno v: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2022 Mar; Vol. 149 (3), pp. 1069-1084. Date of Electronic Publication: 2021 Aug 09.

Not too little, not too much: the impact of mutation types in Wiskott-Aldrich syndrome and RAC2 patients.

Autor: Hsu, Amy P¹ (AUTHOR) amy.hsu@nih.gov

Publikováno v: Clinical & Experimental Immunology. May2023, Vol. 212 Issue 2, p137-146. 10p.