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pro vyhledávání: '"Gonçalo J L, Bernardes"'
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Autor:
Libby Brown, Aldrin V. Vidal, Ana Laura Dias, Tiago Rodrigues, Anna Sigurdardottir, Toby Journeaux, Siobhan O’Brien, Thomas V. Murray, Peter Ravn, Monika Papworth, Gonçalo J. L. Bernardes
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Cyclization provides a general strategy for improving the proteolytic stability, cell membrane permeability and target binding affinity of peptides. Insertion of a stable, non-reducible linker into a disulphide bond is a commonly used approa
Externí odkaz:
https://doaj.org/article/0dbb71bb3e424358b642bfa50634c304
Autor:
Iris A. Bermejo, Ana Guerreiro, Ander Eguskiza, Nuria Martínez-Sáez, Foivos S. Lazaris, Alicia Asín, Víctor J. Somovilla, Ismael Compañón, Tom K. Raju, Srdan Tadic, Pablo Garrido, Josune García-Sanmartín, Vincenzo Mangini, Ana S. Grosso, Filipa Marcelo, Alberto Avenoza, Jesús H. Busto, Fayna García-Martín, Ramón Hurtado-Guerrero, Jesús M. Peregrina, Gonçalo J. L. Bernardes, Alfredo Martínez, Roberto Fiammengo, Francisco Corzana
Publikováno v:
JACS Au, Vol 4, Iss 1, Pp 150-163 (2023)
Externí odkaz:
https://doaj.org/article/874bf93e2a424c2dad381e2f8402117f
Publikováno v:
Angewandte Chemie (International ed. in English)My 5 top papers. 58(48)
"My favorite molecule is cysteine because of its key structural and many, yet unknown, functional roles. My favorite saying is 'Luck takes a damn lot of work' …" Find out more about Gonçalo Bernardes in his Author Profile.
Publikováno v:
Angewandte Chemie. 11/25/2019, Vol. 131 Issue 48, p17264-17264. 1p.
Autor:
Ruth A. Pumroy, Anna D. Protopopova, Tabea C. Fricke, Iris U. Lange, Ferdinand M. Haug, Phuong T. Nguyen, Pamela N. Gallo, Bárbara B. Sousa, Gonçalo J. L. Bernardes, Vladimir Yarov-Yarovoy, Andreas Leffler, Vera Y. Moiseenkova-Bell
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
A non-selective calcium channel transient receptor potential vanilloid 2 (TRPV2) is a potential drug target. Here, the authors employ cryo-electron microscopy, in silico docking, and electrophysiology to identify a binding site for an activator 2-ami
Externí odkaz:
https://doaj.org/article/d877302583004e29b65b3ecd87afcb21
Autor:
Z. Faidon Brotzakis, Philip R. Lindstedt, Ross J. Taylor, Dillon J. Rinauro, Nicholas C. T. Gallagher, Gonçalo J. L. Bernardes, Michele Vendruscolo
Publikováno v:
ACS Central Science, Vol 7, Iss 12, Pp 1986-1995 (2021)
Externí odkaz:
https://doaj.org/article/f7143c06616946c9a1d5d7e6e37fcc04
Autor:
João Conde, Ruth A. Pumroy, Charlotte Baker, Tiago Rodrigues, Ana Guerreiro, Bárbara B. Sousa, Marta C. Marques, Bernardo P. de Almeida, Sohyon Lee, Elvira P. Leites, Daniel Picard, Amrita Samanta, Sandra H. Vaz, Florian Sieglitz, Maike Langini, Marc Remke, Rafael Roque, Tobias Weiss, Michael Weller, Yuhang Liu, Seungil Han, Francisco Corzana, Vanessa A. Morais, Cláudia C. Faria, Tânia Carvalho, Panagis Filippakopoulos, Berend Snijder, Nuno L. Barbosa-Morais, Vera Y. Moiseenkova-Bell, Gonçalo J. L. Bernardes
Publikováno v:
ACS Central Science, Vol 7, Iss 5, Pp 868-881 (2021)
Externí odkaz:
https://doaj.org/article/13e41edb1f1f40069a060c39b209935b
Autor:
Sigitas Mikutis, Muxin Gu, Erdem Sendinc, Madoka E. Hazemi, Hannah Kiely-Collins, Demetrios Aspris, George S. Vassiliou, Yang Shi, Konstantinos Tzelepis, Gonçalo J. L. Bernardes
Publikováno v:
ACS Central Science, Vol 6, Iss 12, Pp 2196-2208 (2020)
Externí odkaz:
https://doaj.org/article/4ce661e34b844c1e93d35c307107b2ca
Publikováno v:
ACS Central Science, Vol 6, Iss 9, Pp 1473-1475 (2020)
Externí odkaz:
https://doaj.org/article/3b525f4a3dd048e7a634751833023266