Evolutionary dynamics in gut-colonizing Candida glabrata during caspofungin therapy: Emergence of clinically important mutations in sphingolipid biosynthesis.

Autor: Hassoun Y; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Aptekmann AA; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Keniya MV; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Gomez RY; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Alayo N; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Novi G; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Quinteros C; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Kaya F; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Zimmerman M; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America., Caceres DH; Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.; Center of Expertise in Mycology Radboudumc/CWZ, Nijmegen, The Netherlands.; Studies in Translational Microbiology and Emerging Diseases (MICROS) Research Group, School of Medicine and Health Sciences, Universidad del Rosario, Bogota, Colombia., Chow NA; Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America., Perlin DS; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America.; Hackensack Meridian School of Medicine, Nutley, New Jersey, United States of America.; Georgetown University Lombardi Comprehensive Cancer Center, Washington, D.C., United States of America., Shor E; Hackensack Meridian Health Center for Discovery and Innovation, Nutley, New Jersey, United States of America.; Hackensack Meridian School of Medicine, Nutley, New Jersey, United States of America.

Publikováno v: PLoS pathogens [PLoS Pathog] 2024 Sep 09; Vol. 20 (9), pp. e1012521. Date of Electronic Publication: 2024 Sep 09 (Print Publication: 2024).