Zobrazeno 1 - 10
of 274
pro vyhledávání: '"Gomez Pinillos, A."'
Autor:
Tomasz M. Beer, Robert DiPaola, Dirk Moore, Xiaomei Liu, Alejandro Gomez-Pinillos, Ethan S. Barnett, James Babb, Mary-Ellen Taplin, Mark N. Stein, Joshi J. Alumkal, Anna C. Ferrari
Supplementary methods and Figure S1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a6405920dc3429a827660650e46372
https://doi.org/10.1158/1078-0432.22472838
https://doi.org/10.1158/1078-0432.22472838
Autor:
Tomasz M. Beer, Robert DiPaola, Dirk Moore, Xiaomei Liu, Alejandro Gomez-Pinillos, Ethan S. Barnett, James Babb, Mary-Ellen Taplin, Mark N. Stein, Joshi J. Alumkal, Anna C. Ferrari
Purpose:This study assesses the action of panobinostat, a histone deacetylase inhibitor (HDACI), in restoring sensitivity to bicalutamide in a castration-resistant prostate cancer (CRPC) model and the efficacy and safety of the panobinostat/bicalutam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87950aab186a81f17fca984be3bf2175
https://doi.org/10.1158/1078-0432.c.6528345.v1
https://doi.org/10.1158/1078-0432.c.6528345.v1
Autor:
Saggu, G., Stroopinsky, D., Arkadiusz Dudek, Olszanski, A. J., Juric, D., Dowlati, A., Vaishampayan, U., Assad, H., Rodon, J., Gibbs, J., Green, J., Du, Z., Rudicell, R., Kannan, K., Gharavi, R., Gomez-Pinillos, A., Fram, R. J., Berger, A., Sachsenmeier, K., Kasar, S.
Publikováno v:
Web of Science
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ba93032aaff6491faf5c7b9fa4c5bf
https://doi.org/10.1016/s0959-8049(22)01134-0
https://doi.org/10.1016/s0959-8049(22)01134-0
Autor:
Liu, XiaoMei, Gomez-Pinillos, Alejandro, Loder, Charisse, Carrillo-de Santa Pau, Enrique, Qiao, Ruifang, Unger, Pamela D., Kurek, Ralf, Oddoux, Carole, Melamed, Jonathan, Gallagher, Robert E., Mandeli, John, Ferrari, Anna C.
Publikováno v:
In The American Journal of Pathology September 2012 181(3):1007-1016
Publikováno v:
In Hematology/Oncology Clinics of North America June 2012 26(3):483-505
Akademický článek
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Autor:
Dirk F. Moore, Anna C. Ferrari, Joshi J. Alumkal, Xiaomei Liu, Ethan S Barnett, Tomasz M. Beer, James S. Babb, Mary-Ellen Taplin, Alejandro Gomez-Pinillos, Robert S. DiPaola, Mark N. Stein
Publikováno v:
Clinical Cancer Research. 25:52-63
Purpose: This study assesses the action of panobinostat, a histone deacetylase inhibitor (HDACI), in restoring sensitivity to bicalutamide in a castration-resistant prostate cancer (CRPC) model and the efficacy and safety of the panobinostat/bicaluta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c31e77e9371ec09b927397ab87d7dc01
https://doi.org/10.1158/1078-0432.ccr-18-1589
https://doi.org/10.1158/1078-0432.ccr-18-1589
Autor:
Alejandro Gomez-Pinillos, Alonzo Martinez, Allison Berger, Amitkumar Mehta, Deborah Berg, Stephane Doucet, Paolo Caimi, Tycel Phillips, Lapo Alinari, Brenda W. Cooper, Bo Chao, Christine K. Ward, Igor Proscurshim, John Gibbs, Sarit Assouline, Alexey V. Danilov, Sharon Friedlander, Steven I. Park
Publikováno v:
Blood. 138:2488-2488
Background: TAK-981 is the first small-molecule inhibitor of SUMOylation to enter clinical trials. SUMOylation is a post-translational modification in which small ubiquitin-like modifier (SUMO) proteins are activated and covalently attached to substr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1901ee75cd090162e6aebd72a827d6ff
https://doi.org/10.1182/blood-2021-152225
https://doi.org/10.1182/blood-2021-152225
Autor:
Sharon Friedlander, Jordi Rodon, Anthony J. Olszanski, Alonzo Martinez, Ulka N. Vaishampayan, Arkadiusz Z. Dudek, Robert Gharavi, John F. Gibbs, Bo Chao, Afshin Dowlati, Christine K. Ward, Bingxia Wang, Alejandro Gomez-Pinillos, Dejan Juric, Vaishali Shinde, Hadeel Assad, Allison Berger, Igor Proscurshim
Publikováno v:
Journal for ImmunoTherapy of Cancer. 9:A505-A506
BackgroundSUMOylation is a post-translational modification that serves as an important modulator of immune responses via its role in constraining the type I interferon (IFN-1) response. TAK-981 is a small molecule that inhibits SUMOylation and increa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f0cf6461cbcb145b372159e18067353
https://doi.org/10.1136/jitc-2021-sitc2021.476
https://doi.org/10.1136/jitc-2021-sitc2021.476
Autor:
Sanjay Goel, Susanna Varkey Ulahannan, Anthony J. Olszanski, Patricia LoRusso, Rachel E. Sanborn, Sunil Sharma, Leisha A. Emens, Matthew Reilley, Victor Priego, Shuli Li, Bingxia Wang, Lixian Dong, Kris Sachsenmeier, John Gibbs, Robert Gharavi, Alonzo Martinez, Igor Proscurshim, Robert J. Fram, Alejandro Gomez-Pinillos, Drew W. Rasco
Publikováno v:
Journal of Clinical Oncology. 40:2506-2506
2506 Background: SUMOylation is a post-translational modification with a role in limiting type 1 interferon (IFN-1)-dependent immune responses. Subasumstat is a small-molecule inhibitor of SUMOylation with the potential to increase antitumor immunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a46a363c8849fbebe7d1252d5011910e
https://doi.org/10.1200/jco.2022.40.16_suppl.2506
https://doi.org/10.1200/jco.2022.40.16_suppl.2506