Pirfenidone increases IL-10 and improves acute pancreatitis in multiple clinically relevant murine models.

Autor: Palathingal Bava E; Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA., George J; Department of Surgery and Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida, USA., Tarique M; Department of Surgery and Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida, USA., Iyer S; Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA., Sahay P; Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA., Gomez Aguilar B; Department of Surgery and Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida, USA., Edwards DB; Department of Surgery and Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida, USA., Giri B; Department of Surgery and Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida, USA., Sethi V; Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA., Jain T; Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA., Sharma P; Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA., Vaish U; Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA., C Jacob HK; Department of Surgery and Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida, USA., Ferrantella A; Department of Surgery and Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida, USA., Maynard CL; Department of Pathology, University of Alabama at Birmingham, Birmingham, Alabama, USA., Saluja AK; Department of Surgery and Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida, USA., Dawra RK; Department of Surgery and Sylvester Comprehensive Cancer Center, University of Miami, Miami, Florida, USA., Dudeja V; Department of Surgery, University of Alabama at Birmingham, Birmingham, Alabama, USA.; Birmingham Veteran Affairs Medical Center, Birmingham, Alabama, USA.

Publikováno v: JCI insight [JCI Insight] 2022 Jan 25; Vol. 7 (2). Date of Electronic Publication: 2022 Jan 25.