Cell number changes in Alzheimer's disease relate to dementia, not to plaques and tangles

Autor: Andrade-Moraes, C. H., Oliveira-Pinto, A. V., Castro-Fonseca, E., Da Silva, C. G., Guimarães, D. M., Szczupak, D., Parente-Bruno, D. R., Carvalho, L. R., Polichiso, L., Gomes, B. V., Oliveira, L. M., Rodriguez, R. D., Leite, R. E., Renata Eloah de Lucena Ferretti-Rebustini, Jacob-Filho, W., Pasqualucci, C. A., Grinberg, L. T., Lent, R.

Publikováno v: Brain : a journal of neurology, vol 136, iss Pt 12
Scopus-Elsevier
Andrade-Moraes, CH; Oliveira-Pinto, AV; Castro-Fonseca, E; da Silva, CG; Guimaraes, DM; Szczupak, D; et al.(2013). Cell number changes in Alzheimer's disease relate to dementia, not to plaques and tangles. BRAIN, 136, 3738-3752. doi: 10.1093/brain/awt273. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/6pk7q6mm

Alzheimer's disease is the commonest cause of dementia in the elderly, but its pathological determinants are still debated. Amyloid-β plaques and neurofibrillary tangles have been implicated either directly as disruptors of neural function, or indir

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https://escholarship.org/uc/item/6pk7q6mm

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