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Transcript and protein expression analysis of proteases in the blood stages of Plasmodium falciparum
Publikováno v:
In Experimental Parasitology September 2017 180:33-44
Autor:
Cletus A. Wezena, Romy Alisch, Alexandra Golzmann, Linda Liedgens, Verena Staudacher, Gabriele Pradel, Marcel Deponte
Publikováno v:
Microbial Cell, Vol 5, Iss 1, Pp 32-41 (2017)
The enzymes glyoxalase 1 and 2 (Glo1 and Glo2) are found in most eukaryotes and catalyze the glutathione-dependent conversion of 2-oxoaldehydes to 2-hydroxycarboxylic acids. Four glyoxalases are encoded in the genome of the malaria parasite Plasmodiu
Externí odkaz:
https://doaj.org/article/08bd2ce354c84c5fb990859f4b4b60e6
Autor:
Schmidt, Ines, Pradel, Gabriele, Sologub, Ludmilla, Golzmann, Alexandra, Ngwa, Che J., Kucharski, Anna, Schirmeister, Tanja, Holzgrabe, Ulrike
Publikováno v:
In Bioorganic & Medicinal Chemistry 15 August 2016 24(16):3636-3642
Akademický článek
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Autor:
Sarah Krieg, Fabian Pott, Laura Potthoff, Maud Verheirstraeten, Mareike Bütepage, Alexandra Golzmann, Barbara Lippok, Christine Goffinet, Bernhard Lüscher, Patricia Korn
Publikováno v:
Cellular and molecular life sciences : (CMLS) 80(3), 72 (2023). doi:10.1007/s00018-023-04717-8
Cellular and molecular life sciences : (CMLS) 80(3), 72 (2023). doi:10.1007/s00018-023-04717-8
Published by Springer International Publishing AG, Cham (ZG)
Published by Springer International Publishing AG, Cham (ZG)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f277f5fda77165b3d04c94ea835f278
https://lirias.kuleuven.be/handle/20.500.12942/716303
https://lirias.kuleuven.be/handle/20.500.12942/716303
Autor:
Lisa Weixler, Nonso Josephat Ikenga, Jim Voorneveld, Gülcan Aydin, Timo MHR Bolte, Jeffrey Momoh, Mareike Bütepage, Alexandra Golzmann, Bernhard Lüscher, Dmitri V Filippov, Roko Žaja, Karla LH Feijs
Publikováno v:
Life Science Alliance, 6(1):e202201455. LIFE SCIENCE ALLIANCE LLC
The modification of substrates with ADP-ribose (ADPr) is important in, for example, antiviral immunity and cancer. Recently, several reagents were developed to detect ADP-ribosylation; however, it is unknown whether they recognise ADPr, specific amin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ddeb2b89326336609417ed66fe13094
https://pubmed.ncbi.nlm.nih.gov/36368907
https://pubmed.ncbi.nlm.nih.gov/36368907
Autor:
Lisa Weixler, Jim Voorneveld, Gülcan Aydin, Timo M. H. R. Bolte, Jeffrey Momoh, Mareike Bütepage, Alexandra Golzmann, Bernhard Lüscher, Dmitri V. Filippov, Roko Žaja, Karla L. H. Feijs
Recent evidence suggests that modification of substrates with a single ADP-ribose (ADPr) is important in for example antiviral immunity and cancer. However, the endogenous substrates and the extent of mono-ADP-ribosylation are still largely unclear.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e986423c5c4d15b274fe379cbe0779a
https://doi.org/10.1101/2022.02.22.481411
https://doi.org/10.1101/2022.02.22.481411
Akademický článek
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Autor:
Weixler, Lisa, Ikenga, Nonso Josephat, Voorneveld, Jim, Aydin, Gülcan, Bolte, Timo M. H. R., Momoh, Jeffrey, Bütepage, Mareike, Golzmann, Alexandra, Lüscher, Bernhard, Filippov, Dmitri V., Žaja, Roko, Feijs, Karla L. H.
Publikováno v:
Life Science Alliance; Jan2023, Vol. 6 Issue 1, p1-19, 19p
Autor:
Gabriele Pradel, Ines Schmidt, Che Julius Ngwa, Alexandra Golzmann, Ludmilla Sologub, Tanja Schirmeister, Anna Kucharski, Ulrike Holzgrabe
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:3636-3642
Linking two tacrine molecules results in a tremendous increase of activity against Plasmodia in comparison to the monomer. This finding prompted the synthesis of a library of monomeric and dimeric tacrine derivatives in order to derive structure-acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d69e41f5df5b0ca137dae16130405db1
https://doi.org/10.1016/j.bmc.2016.06.003
https://doi.org/10.1016/j.bmc.2016.06.003