Association of Left Ventricular Systolic Dysfunction Among Carriers of Truncating Variants in Filamin C With Frequent Ventricular Arrhythmia and End-stage Heart Failure

Autor: Akhtar, MM, Lorenzini, M, Pavlou, M, Ochoa, JP, O'Mahony, C, Restrepo-Cordoba, MA, Segura-Rodriguez, D, Bermudez-Jimenez, F, Molina, P, Cuenca, S, Ader, F, Larranaga-Moreira, JM, Sabater-Molina, M, Garcia-Alvarez, MI, Arantzamendi, LG, Truszkowska, G, Ortiz-Genga, M, Ruiz, IS, Nielsen, SK, Rasmussen, TB, Mezcua, AR, Alvarez-Rubio, J, Eiskjaer, H, Gautel, M, Garcia-Pinilla, JM, Ripoll-Vera, T, Mogensen, J, Freire, JL, Rodriguez-Palomares, JF, Pena-Pena, ML, Rangel-Sousa, D, Palomino-Doza, J, Achaga, XA, Bilinska, Z, Golvano, EZ, Climent, V, Penalver, MN, Barriales-Villa, R, Charron, P, Yotti, R, Zorio, E, Jimenez-Jaimez, J, Garcia-Pavia, P, Elliott, PM, European Genetic Cardiomyopathies

Publikováno v: JAMA Cardiology
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
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r-IIS La Fe. Repositorio Institucional de Producción Científica del Instituto de Investigación Sanitaria La Fe

IMPORTANCE Truncating variants in the gene encoding filamin C (FLNCtv) are associated with arrhythmogenic and dilated cardiomyopathies with a reportedly high risk of ventricular arrhythmia. OBJECTIVE To determine the frequency of and risk factors ass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b6042053eec522b6ee37eb71853f459a
https://jamanetwork.com/journals/jamacardiology/article-abstract/2779769