Dual inhibition of MAPK and PI3K/AKT pathways enhances maturation of human iPSC-derived cardiomyocytes.

Autor: Garay BI; Lillehei Heart Institute (LHI), Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA; Department of Neuroscience, University of Minnesota, Minneapolis, MN, USA., Givens S; Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA; Stem Cell Institute, University of Minnesota, Minneapolis, MN, USA., Abreu P; Lillehei Heart Institute (LHI), Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA., Liu M; Lillehei Heart Institute (LHI), Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA., Yücel D; Integrative Biology and Physiology, University of Minnesota, Minneapolis, MN, USA., Baik J; Lillehei Heart Institute (LHI), Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA., Stanis N; Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA., Rothermel TM; Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA., Magli A; Lillehei Heart Institute (LHI), Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA., Abrahante JE; University of Minnesota Informatics Institute, Minneapolis, MN, USA., Goloviznina NA; Molecular, Cellular, Developmental Biology and Genetics, University of Minnesota, Minneapolis, MN, USA; LHI, Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA., Soliman HAN; LHI, Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA., Dhoke NR; Lillehei Heart Institute (LHI), Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA., Kyba M; Stem Cell Institute, University of Minnesota, Minneapolis, MN, USA; Molecular, Cellular, Developmental Biology and Genetics, University of Minnesota, Minneapolis, MN, USA; LHI, Department of Pediatrics, University of Minnesota Medical School, Minneapolis, MN, USA., Alford PW; Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA., Dudley SC Jr; Lillehei Heart Institute (LHI), Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA., van Berlo JH; Lillehei Heart Institute (LHI), Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA; Stem Cell Institute, University of Minnesota, Minneapolis, MN, USA; Integrative Biology and Physiology, University of Minnesota, Minneapolis, MN, USA., Ogle B; Biomedical Engineering, University of Minnesota, Minneapolis, MN, USA; Stem Cell Institute, University of Minnesota, Minneapolis, MN, USA., Perlingeiro RRC; Lillehei Heart Institute (LHI), Department of Medicine, University of Minnesota Medical School, Minneapolis, MN, USA; Department of Neuroscience, University of Minnesota, Minneapolis, MN, USA; Stem Cell Institute, University of Minnesota, Minneapolis, MN, USA; Integrative Biology and Physiology, University of Minnesota, Minneapolis, MN, USA; Molecular, Cellular, Developmental Biology and Genetics, University of Minnesota, Minneapolis, MN, USA. Electronic address: perli032@umn.edu.

Publikováno v: Stem cell reports [Stem Cell Reports] 2022 Sep 13; Vol. 17 (9), pp. 2005-2022. Date of Electronic Publication: 2022 Aug 04.

Twist of fate for skeletal muscle mesenchymal cells.

Autor: Goloviznina NA; Lillehei Heart Institute, and Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota 55455, USA., Kyba M; Lillehei Heart Institute, and Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota 55455, USA.

Publikováno v: Nature cell biology [Nat Cell Biol] 2017 Mar 01; Vol. 19 (3), pp. 153-154.

Phenotypic correction of Fanconi anemia cells in the murine bone marrow after carrier cell mediated delivery of lentiviral vector.

Autor: Chakkaramakkil Verghese S; Department of Pediatrics, Oregon Health & Science University, Portland, OR, 97239, USA. chakkara@ohsu.edu.; Papé Family Pediatric Research Institute, Oregon Health & Science University, L321, Portland, OR, 97239, USA. chakkara@ohsu.edu., Goloviznina NA; Department of Pediatrics, Oregon Health & Science University, Portland, OR, 97239, USA.; Papé Family Pediatric Research Institute, Oregon Health & Science University, L321, Portland, OR, 97239, USA.; Present address: Molecular, Cellular, Developmental Biology and Genetics, University of Minnesota, Minneapolis, MN, 55455, USA., Kurre P; Department of Pediatrics, Oregon Health & Science University, Portland, OR, 97239, USA.; Papé Family Pediatric Research Institute, Oregon Health & Science University, L321, Portland, OR, 97239, USA.

Publikováno v: Stem cell research & therapy [Stem Cell Res Ther] 2016 Nov 19; Vol. 7 (1), pp. 170. Date of Electronic Publication: 2016 Nov 19.

Endogenous DNA Damage Leads to p53-Independent Deficits in Replicative Fitness in Fetal Murine Fancd2 ^-/- Hematopoietic Stem and Progenitor Cells.

Autor: Yoon YM; Department of Pediatrics, Oregon Health & Science University, Portland, OR 97239, USA; Papé Family Pediatric Research Institute, Oregon Health & Science University, Portland, OR 97239, USA; Pediatric Cancer Biology Program, Oregon Health & Science University, Portland, OR 97239, USA., Storm KJ; Department of Pediatrics, Oregon Health & Science University, Portland, OR 97239, USA; Papé Family Pediatric Research Institute, Oregon Health & Science University, Portland, OR 97239, USA; Pediatric Cancer Biology Program, Oregon Health & Science University, Portland, OR 97239, USA., Kamimae-Lanning AN; Department of Pediatrics, Oregon Health & Science University, Portland, OR 97239, USA; Papé Family Pediatric Research Institute, Oregon Health & Science University, Portland, OR 97239, USA; Pediatric Cancer Biology Program, Oregon Health & Science University, Portland, OR 97239, USA., Goloviznina NA; Department of Pediatrics, Oregon Health & Science University, Portland, OR 97239, USA; Papé Family Pediatric Research Institute, Oregon Health & Science University, Portland, OR 97239, USA; Pediatric Cancer Biology Program, Oregon Health & Science University, Portland, OR 97239, USA., Kurre P; Department of Pediatrics, Oregon Health & Science University, Portland, OR 97239, USA; Papé Family Pediatric Research Institute, Oregon Health & Science University, Portland, OR 97239, USA; Pediatric Cancer Biology Program, Oregon Health & Science University, Portland, OR 97239, USA; OHSU Knight Cancer Institute, Oregon Health & Science University, 3181 Southwest Sam Jackson Park Road, Portland, OR 97239, USA. Electronic address: kurrepe@ohsu.edu.

Publikováno v: Stem cell reports [Stem Cell Reports] 2016 Nov 08; Vol. 7 (5), pp. 840-853. Date of Electronic Publication: 2016 Oct 06.

Serum Exosome MicroRNA as a Minimally-Invasive Early Biomarker of AML.

Autor: Hornick NI; 1] Department of Pediatrics, Oregon Health &Science University, Portland, OR [2] Department of Medicine, Oregon Health &Science University, Portland, OR [3] Papé Family Pediatric Research Institute, Oregon Health &Science University, Portland, OR., Huan J; 1] Department of Pediatrics, Oregon Health &Science University, Portland, OR [2] Department of Medicine, Oregon Health &Science University, Portland, OR [3] Papé Family Pediatric Research Institute, Oregon Health &Science University, Portland, OR., Doron B; 1] Department of Pediatrics, Oregon Health &Science University, Portland, OR [2] Department of Medicine, Oregon Health &Science University, Portland, OR [3] Papé Family Pediatric Research Institute, Oregon Health &Science University, Portland, OR., Goloviznina NA; 1] Department of Pediatrics, Oregon Health &Science University, Portland, OR [2] Department of Medicine, Oregon Health &Science University, Portland, OR [3] Papé Family Pediatric Research Institute, Oregon Health &Science University, Portland, OR., Lapidus J; Department of Public Health, Oregon Health &Science University, Portland, OR., Chang BH; 1] Department of Pediatrics, Oregon Health &Science University, Portland, OR [2] Department of Medicine, Oregon Health &Science University, Portland, OR [3] Papé Family Pediatric Research Institute, Oregon Health &Science University, Portland, OR [4] Knight Cancer Institute, Oregon Health &Science University, Portland, OR., Kurre P; 1] Department of Pediatrics, Oregon Health &Science University, Portland, OR [2] Department of Medicine, Oregon Health &Science University, Portland, OR [3] Papé Family Pediatric Research Institute, Oregon Health &Science University, Portland, OR [4] Knight Cancer Institute, Oregon Health &Science University, Portland, OR.

Publikováno v: Scientific reports [Sci Rep] 2015 Jun 12; Vol. 5, pp. 11295. Date of Electronic Publication: 2015 Jun 12.