High resolution imaging and five-year tuberculosis contact outcomes.

Autor: Esmail H; Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, Republic of South Africa.; MRC Clinical Trials Unit at University College London, WC1V 6LJ, United Kingdom.; WHO Collaborating Centre for Tuberculosis Research and Innovation, Institute for Global Health, University College London, WC1E 6JB, United Kingdom., Coussens AK; Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, Republic of South Africa.; Infectious Diseases and Immune Defence Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3052, Australia., Thienemann F; Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, Republic of South Africa.; Department of Internal Medicine, University Hospital of Zurich, University of Zurich, Switzerland., Sossen B; Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, Republic of South Africa., Mukasa SL; Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, Republic of South Africa., Warwick J; Division of Nuclear Medicine, Department of Medical Imaging and Clinical Oncology, Stellenbosch University, Cape Town, South Africa., Goliath RT; Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, Republic of South Africa., Davies NO; Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, Republic of South Africa., Douglass E; Division of Infectious Diseases, Center for Emerging Pathogens, New Jersey Medical School, Rutgers University, Newark, NJ, USA., Jackson A; Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, Republic of South Africa., Lakay F; Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, Republic of South Africa., Streicher E; Department of Science and Technology/National Research Foundation Centre of Excellence in Biomedical Tuberculosis Research, South African Medical Research Council for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa., Munro JE; Department of Medical Biology, University of Melbourne, Parkville, 3052, Australia.; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia., Barrios MH; Department of Medical Biology, University of Melbourne, Parkville, 3052, Australia.; Advanced Genomics Facility, Advanced Technology and Biology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia., Heinsohn T; Department of Epidemiology, Helmholtz Centre for Infection Research, Braunschweig, Germany., Macpherson L; MRC Clinical Trials Unit at University College London, WC1V 6LJ, United Kingdom., Sheerin D; Infectious Diseases and Immune Defence Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, 3052, Australia., Aziz S; Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, Republic of South Africa., Serole K; Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, Republic of South Africa., Daroowala R; Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, Republic of South Africa., Taliep A; Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, Republic of South Africa., Ahlers P; Department of Science and Technology/National Research Foundation Centre of Excellence in Biomedical Tuberculosis Research, South African Medical Research Council for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa., Malherbe ST; Department of Science and Technology/National Research Foundation Centre of Excellence in Biomedical Tuberculosis Research, South African Medical Research Council for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa., Bowden R; Department of Medical Biology, University of Melbourne, Parkville, 3052, Australia.; Advanced Genomics Facility, Advanced Technology and Biology Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia., Warren R; Department of Science and Technology/National Research Foundation Centre of Excellence in Biomedical Tuberculosis Research, South African Medical Research Council for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa., Walzl G; Department of Science and Technology/National Research Foundation Centre of Excellence in Biomedical Tuberculosis Research, South African Medical Research Council for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Health Sciences, Stellenbosch University, Cape Town, South Africa., Via LE; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.; Tuberculosis Imaging Program, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD., Bahlo M; Department of Medical Biology, University of Melbourne, Parkville, 3052, Australia.; Population Health and Immunity Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia., Jacobson KR; Section of Infectious Diseases, Boston University Chobanian and Avedisian School of Medicine and Boston Medical Center, Boston, MA, USA.; Department of Epidemiology, Boston University School of Public Health Boston, MA, USA., Horsburgh CR Jr; Department of Epidemiology, Boston University School of Public Health Boston, MA, USA., Salgame P; Division of Infectious Diseases, Center for Emerging Pathogens, New Jersey Medical School, Rutgers University, Newark, NJ, USA., Alland D; Public Health Research Institute, New Jersey Medical School, Rutgers University, Newark, NJ, USA., Barry CE 3rd; Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, Republic of South Africa.; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD.; Tuberculosis Imaging Program, Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD., Flynn JL; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, PA 15261, United States of America., Ellner JJ; Division of Infectious Diseases, Center for Emerging Pathogens, New Jersey Medical School, Rutgers University, Newark, NJ, USA., Wilkinson RJ; Centre for Infectious Diseases Research in Africa, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Observatory 7925, Republic of South Africa.; The Francis Crick Institute London NW1 1AT, United Kingdom.; Department of Infectious Diseases, Imperial College London W12 0NN, United Kingdom.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Jul 03. Date of Electronic Publication: 2023 Jul 03.

Tuberculosis, HIV and the association with transient hyperglycaemia in peri-urban South Africa

Autor: Kubjane, M, Berkowitz, N, Goliath, RT, Levitt, N, Wilkinson, RJ, Oni, T

Background Diabetes mellitus (DM) increases tuberculosis (TB) risk. We assessed the prevalence of hyperglycaemia (DM and impaired glucose regulation (IGR)) in TB patients and the association between hyperglycaemia and TB at enrolment and 3 months aft

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::fa03acce7504eb18c5da60de66bfc946
http://hdl.handle.net/10044/1/73374

Effect of HIV on the frequency and number of Mycobacterium tuberculosis-specific CD4+ T cells in blood and the airways in latent tuberculosis infection

Autor: Bunjun, R, Riou, C, Soares, AP, Thawer, N, Müller, TL, Kiravu, A, Ginbot, Z, Oni, T, Goliath, RT, Kalsdorf, B, Von Groote-Bidlingmaier, F, Hanekom, W, Walzl, G, Wilkinson, RJ, Burgers, W

HIV-1 infection substantially increases the risk of developing tuberculosis (TB). There is extensive depletion of Mycobacterium tuberculosis (M.tuberculosis)-specific CD4+ T cells in blood in early HIV infection, but little is known about responses i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::71e7ba04e7217831b913374b105bf82a
http://hdl.handle.net/10044/1/56694

Relationship of SARS-CoV-2-specific CD4 response to COVID-19 severity and impact of HIV-1 and tuberculosis coinfection.

Autor: Riou C; Wellcome Centre for Infectious Disease Research in Africa and Institute of Infectious Disease and Molecular Medicine.; Division of Medical Virology, Department of Pathology, and., du Bruyn E; Wellcome Centre for Infectious Disease Research in Africa and Institute of Infectious Disease and Molecular Medicine.; Department of Medicine, University of Cape Town, Cape Town, South Africa., Stek C; Wellcome Centre for Infectious Disease Research in Africa and Institute of Infectious Disease and Molecular Medicine.; Department of Medicine, University of Cape Town, Cape Town, South Africa.; Department of Infectious Diseases, Imperial College London, London, United Kingdom., Daroowala R; Wellcome Centre for Infectious Disease Research in Africa and Institute of Infectious Disease and Molecular Medicine.; Department of Medicine, University of Cape Town, Cape Town, South Africa.; Department of Infectious Diseases, Imperial College London, London, United Kingdom., Goliath RT; Wellcome Centre for Infectious Disease Research in Africa and Institute of Infectious Disease and Molecular Medicine., Abrahams F; Wellcome Centre for Infectious Disease Research in Africa and Institute of Infectious Disease and Molecular Medicine., Said-Hartley Q; Department of Radiology, University of Cape Town, Cape Town, South Africa., Allwood BW; Division of Pulmonology, Department of Medicine, Stellenbosch University and Tygerberg Hospital, Cape Town, South Africa., Hsiao NY; Division of Medical Virology, Department of Pathology, and.; National Health Laboratory Service, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa., Wilkinson KA; Wellcome Centre for Infectious Disease Research in Africa and Institute of Infectious Disease and Molecular Medicine.; Department of Medicine, University of Cape Town, Cape Town, South Africa.; The Francis Crick Institute, London, United Kingdom., Arlehamn CSL; Center for Infectious Disease, La Jolla Institute for Immunology, La Jolla, California, USA., Sette A; Center for Infectious Disease, La Jolla Institute for Immunology, La Jolla, California, USA.; Department of Medicine, School of Medicine, University of California San Diego, La Jolla, California, USA., Wasserman S; Wellcome Centre for Infectious Disease Research in Africa and Institute of Infectious Disease and Molecular Medicine.; Department of Medicine, University of Cape Town, Cape Town, South Africa., Wilkinson RJ; Wellcome Centre for Infectious Disease Research in Africa and Institute of Infectious Disease and Molecular Medicine.; Department of Medicine, University of Cape Town, Cape Town, South Africa.; Department of Infectious Diseases, Imperial College London, London, United Kingdom.; The Francis Crick Institute, London, United Kingdom.

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2021 Jun 15; Vol. 131 (12).

Disease extent and anti-tubercular treatment response correlates with Mycobacterium tuberculosis -specific CD4 T-cell phenotype regardless of HIV-1 status.

Autor: Riou C; Wellcome Centre for Infectious Disease Research in Africa Institute of Infectious Disease and Molecular Medicine University of Cape Town Observatory South Africa.; Division of Immunology Department of Pathology University of Cape Town Observatory South Africa., Du Bruyn E; Wellcome Centre for Infectious Disease Research in Africa Institute of Infectious Disease and Molecular Medicine University of Cape Town Observatory South Africa., Ruzive S; Wellcome Centre for Infectious Disease Research in Africa Institute of Infectious Disease and Molecular Medicine University of Cape Town Observatory South Africa., Goliath RT; Wellcome Centre for Infectious Disease Research in Africa Institute of Infectious Disease and Molecular Medicine University of Cape Town Observatory South Africa., Lindestam Arlehamn CS; Division of Vaccine Discovery La Jolla Institute for Immunology La Jolla CA USA., Sette A; Division of Vaccine Discovery La Jolla Institute for Immunology La Jolla CA USA.; Department of Medicine University of California San Diego La Jolla CA USA., Sher A; Immunobiology Section Laboratory of Parasitic Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda MD USA., Barber DL; T Lymphocyte Biology Section Laboratory of Parasitic Diseases National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda MD USA., Wilkinson RJ; Wellcome Centre for Infectious Disease Research in Africa Institute of Infectious Disease and Molecular Medicine University of Cape Town Observatory South Africa.; Department of Infectious Diseases Imperial College London London UK.; Department of Medicine University of Cape Town Observatory South Africa.; The Francis Crick Institute London UK.

Publikováno v: Clinical & translational immunology [Clin Transl Immunology] 2020 Sep 28; Vol. 9 (9), pp. e1176. Date of Electronic Publication: 2020 Sep 28 (Print Publication: 2020).