Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL.

Autor: Wang L; Cancer Vaccine Center, and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA;, Shalek AK; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA;, Lawrence M; Broad Institute, Cambridge, MA;, Ding R; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA;, Gaublomme JT; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA;, Pochet N; Broad Institute, Cambridge, MA;, Stojanov P; Broad Institute, Cambridge, MA;, Sougnez C; Broad Institute, Cambridge, MA;, Shukla SA; Cancer Vaccine Center, and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA;, Stevenson KE; Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA;, Zhang W; Cancer Vaccine Center, and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA;, Wong J; Cancer Vaccine Center, and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA;, Sievers QL; Cancer Vaccine Center, and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA;, MacDonald BT; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA; Department of Neurology, Harvard Medical School, Boston, MA;, Vartanov AR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA;, Goldstein NR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA;, Neuberg D; Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, MA;, He X; F. M. Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA; Department of Neurology, Harvard Medical School, Boston, MA;, Lander E; Broad Institute, Cambridge, MA;, Hacohen N; Broad Institute, Cambridge, MA; Division of Allergy, Immunology and Rheumatology, Department of Medicine, Massachusetts General Hospital, Boston MA; and., Regev A; Broad Institute, Cambridge, MA;, Getz G; Broad Institute, Cambridge, MA;, Brown JR; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA., Park H; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA;, Wu CJ; Cancer Vaccine Center, and Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA; Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

Publikováno v: Blood [Blood] 2014 Aug 14; Vol. 124 (7), pp. 1089-98. Date of Electronic Publication: 2014 Apr 28.

Autologous CLL cell vaccination early after transplant induces leukemia-specific T cells.

Autor: Burkhardt UE; Cancer Vaccine Center, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA., Hainz U, Stevenson K, Goldstein NR, Pasek M, Naito M, Wu D, Ho VT, Alonso A, Hammond NN, Wong J, Sievers QL, Brusic A, McDonough SM, Zeng W, Perrin A, Brown JR, Canning CM, Koreth J, Cutler C, Armand P, Neuberg D, Lee JS, Antin JH, Mulligan RC, Sasada T, Ritz J, Soiffer RJ, Dranoff G, Alyea EP, Wu CJ

Publikováno v: The Journal of clinical investigation [J Clin Invest] 2013 Sep; Vol. 123 (9), pp. 3756-65. Date of Electronic Publication: 2013 Aug 05.