Efficacy and safety of gluten peptide-based antigen-specific immunotherapy (Nexvax2) in adults with coeliac disease after bolus exposure to gluten (RESET CeD): an interim analysis of a terminated randomised, double-blind, placebo-controlled phase 2 study

Autor: Adams, Atoya, Andrews, Jane M, Behrend, Clint E, Brown, Gregor J E, Chen Yi Mei, Swee Lin, Coates, Allan G, DiMarino, Anthony J, Ee, Hooi, Elliott, David E, Epstein, Roger M, Feyen, Bryan John, Fogel, Ronald P, Friedenberg, Keith Alan, Gearry, Richard B, Gerdis, Michael S, Goldstein, Michael J, Gupta, Vipin K, Holmes, Robert John, Holtmann, Gerald J, Idarraga, Samuel H, James, George W, King, Tim, Klein, Terry D, Kupfer, Sonia S, Lebwohl, Benjamin, Lowe, Matthew John, Murray, Joseph A, Newton, Eric B, Quinn, Dean, Radin, David M, Ritter, Timothy E, Stacey, Helen Lee, Strout, Cynthia B, Stubbs, Richard S, Thackwray, Susan Lynn, Trivedi, Vivek M, Weber, John R, Wilson, Scott A, Tye-Din, Jason A, Daveson, A James M, Goel, Gautam, Goldstein, Kaela E, Hand, Holly L, Neff, Kristin M, Popp, Alina, Taavela, Juha, Maki, Markku, Isola, Jorma, Williams, Leslie J, Truitt, Kenneth E, Anderson, Robert P ^*

Publikováno v: In The Lancet Gastroenterology & Hepatology May 2023 8(5):446-457

Epitope-specific immunotherapy targeting CD4-positive T cells in coeliac disease: two randomised, double-blind, placebo-controlled phase 1 studies

Autor: Goel, Gautam, King, Tim, Daveson, A James, Andrews, Jane M, Krishnarajah, Janakan, Krause, Richard, Brown, Gregor J E, Fogel, Ronald, Barish, Charles F, Epstein, Roger, Kinney, Timothy P, Miner, Philip B, Jr, Tye-Din, Jason A, Girardin, Adam, Taavela, Juha, Popp, Alina, Sidney, John, Mäki, Markku, Goldstein, Kaela E, Griffin, Patrick H, Wang, Suyue, Dzuris, John L, Williams, Leslie J, Sette, Alessandro, Xavier, Ramnik J, Sollid, Ludvig M, Jabri, Bana, Anderson, Robert P

Publikováno v: In The Lancet Gastroenterology & Hepatology July 2017 2(7):479-493

Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease

Autor: Goel, Gautam, Tye-Din, Jason A., Qiao, Shuo Wang, Russell, Amy K., Mayassi, Toufic, Ciszewski, Cezary, Sarna, Vikas Kumar, Wang, Suyue, Goldstein, Kaela E., Dzuris, John L., Williams, Leslie J., Xavier, Ramnik J., Lundin, Knut Erik Aslaksen, Jabri, Bana, Sollid, Ludvig Magne, Anderson, Robert P.

Publikováno v: Goel, Gautam Tye-Din, Jason A. Qiao, Shuo Wang Russell, Amy K. Mayassi, Toufic Ciszewski, Cezary Sarna, Vikas Kumar Wang, Suyue Goldstein, Kaela E. Dzuris, John L. Williams, Leslie J. Xavier, Ramnik J. Lundin, Knut Erik Aslaksen Jabri, Bana Sollid, Ludvig Magne Anderson, Robert P. . Cytokine release and gastrointestinal symptoms after gluten challenge in celiac disease. Science Advances. 2019, 5:eaaw7756(8), 1-15
Science Advances

Externí odkaz: http://hdl.handle.net/10852/77138
https://www.duo.uio.no/bitstream/handle/10852/77138/2/eaaw7756.full.pdf

Additional file 1 of Patient factors influencing acute gluten reactions and cytokine release in treated coeliac disease

Autor: Tye-Din, Jason A., A. James M. Daveson, Goldstein, Kaela E., Hand, Holly L., Neff, Kristin M., Goel, Gautam, Williams, Leslie J., Truitt, Kenneth E., Anderson, Robert P.

Additional file 1: Table S1. Number (%) of participants using a qualitative descriptor and corresponding numerical score for peak global digestive symptom severity (GloSS) after gluten challenge. Table S2. Patients’ ability to predict their most tr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fff127d786c282215def51d567d84af

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