Analysis of sequence variations in the suppressor of cytokine signaling (SOCS)-3 gene in extremely obese children and adolescents

Autor: Goldschmidt Hanspeter, Siegfried Wolfgang, Scherag André, Wermter Anne-Kathrin, Hölter Katja, Hebebrand Johannes, Hinney Anke

Publikováno v: BMC Medical Genetics, Vol 8, Iss 1, p 21 (2007)

Abstract Background The suppressor of cytokine signaling (SOCS)-3 is a negative feedback regulator of cytokine signaling and also influences leptin signaling. We investigated association of variations in the coding sequence and promoter region of SOC

Externí odkaz: https://doaj.org/article/eeabc2435f484f749c3a4bd02ac3f489

No evidence for involvement of the calpain-10 gene `high-risk' haplotype combination for non-insulin-dependent diabetes mellitus in early onset obesity

Autor: Hinney, Anke¹ anke.hinney@med.uni-marburg.de, Antwerpen, Benjamin¹, Geller, Frank², Schäfer, Helmut², Siegfried, Wolfgang³, Goldschmidt, Hanspeter⁴, Remschmidt, Helmut¹, Ziegler, Andreas², Hebebrand, Johannes¹

Publikováno v: Molecular Genetics & Metabolism. Jun2002, Vol. 76 Issue 2, p152. 5p.

Melanocortin-4 receptor gene: case-control study and transmission disequilibrium test confirm that functionally relevant mutations are compatible with a major gene effect for extreme obesity.

Autor: Hinney A; Clinical Research Group, Department of Child and Adolescent Psychiatry, Philipps-University of Marburg, D-35039 Marburg, Germany. anke.hinney@med.uni-marburg.de, Hohmann S, Geller F, Vogel C, Hess C, Wermter AK, Brokamp B, Goldschmidt H, Siegfried W, Remschmidt H, Schäfer H, Gudermann T, Hebebrand J

Publikováno v: The Journal of clinical endocrinology and metabolism [J Clin Endocrinol Metab] 2003 Sep; Vol. 88 (9), pp. 4258-67.