Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Goldman, Alastair S.H."'
Yes
R-loops are by-products of transcription that must be tightly regulated to maintain genomic stability and gene expression. Here, we describe a mechanism for the regulation of the Rloop- specific helicase, senataxin (SETX), and identify the u
R-loops are by-products of transcription that must be tightly regulated to maintain genomic stability and gene expression. Here, we describe a mechanism for the regulation of the Rloop- specific helicase, senataxin (SETX), and identify the u
Externí odkaz:
http://hdl.handle.net/10454/18592
Autor:
Hunt, L.J., Ahmed, E.A., Kaur, H., Ahuja, J.S., Hulme, L., Chou, T.C., Lichten, M., Goldman, Alastair S.H.
Yes
We investigated the meiotic role of Srs2, a multi-functional DNA helicase/translocase that destabilises Rad51-DNA filaments and is thought to regulate strand invasion and prevent hyper-recombination during the mitotic cell cycle. We find tha
We investigated the meiotic role of Srs2, a multi-functional DNA helicase/translocase that destabilises Rad51-DNA filaments and is thought to regulate strand invasion and prevent hyper-recombination during the mitotic cell cycle. We find tha
Externí odkaz:
http://hdl.handle.net/10454/17048
Yes
Integrating a desired DNA sequence into the yeast genomes is a widely-used genetic manipulation in the budding yeast Saccharomyces cerevisiae. The conventional integration method is to use an integrative plasmid such as pRS or YIplac series
Integrating a desired DNA sequence into the yeast genomes is a widely-used genetic manipulation in the budding yeast Saccharomyces cerevisiae. The conventional integration method is to use an integrative plasmid such as pRS or YIplac series
Externí odkaz:
http://hdl.handle.net/10454/17333
Yes
The budding yeast genome contains regions where meiotic recombination initiates more frequently than in others. This pattern parallels enrichment for the meiotic chromosome axis proteins Hop1 and Red1. These proteins are important for Spo11-
The budding yeast genome contains regions where meiotic recombination initiates more frequently than in others. This pattern parallels enrichment for the meiotic chromosome axis proteins Hop1 and Red1. These proteins are important for Spo11-
Externí odkaz:
http://hdl.handle.net/10454/17330
Yes
In the section “Generation of phospho-specific Hop1 antibodies” of the Materials and Methods, we made several mistakes when indicating the sequence of the peptides used for the generation of antibodies.
Erratum: Penedos A, Johnson A
In the section “Generation of phospho-specific Hop1 antibodies” of the Materials and Methods, we made several mistakes when indicating the sequence of the peptides used for the generation of antibodies.
Erratum: Penedos A, Johnson A
Externí odkaz:
http://hdl.handle.net/10454/17332
Yes
A hallmark of the conserved ATM/ATR signalling is its ability to mediate a wide range of functions utilizing only a limited number of adaptors and effector kinases. During meiosis, Tel1 and Mec1, the budding yeast ATM and ATR, respectively,
A hallmark of the conserved ATM/ATR signalling is its ability to mediate a wide range of functions utilizing only a limited number of adaptors and effector kinases. During meiosis, Tel1 and Mec1, the budding yeast ATM and ATR, respectively,
Externí odkaz:
http://hdl.handle.net/10454/17331
Autor:
Hunt, Laura J, Ahmed, Emad, Kaur, Hardeep, Ahuja, Jasvinder, Hulme, Lydia, Chou, Ta-Chung, Lichten, Michael, Goldman, Alastair S.H.
We investigated the meiotic role of Srs2, a multi-functional DNA helicase/translocase that destabilizes Rad51-DNA filaments, and is thought to regulate strand invasion and prevent hyper-recombination during the mitotic cell cycle. We find that Srs2 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=sharebioRxiv::755fe16517751968482dc6334893d501
Autor:
Borde, Valerie, Goldman, Alastair S.H.
Publikováno v:
Science. 10/27/2000, Vol. 290 Issue 5492, p806-809. 4p. 4 Graphs.
Publikováno v:
Annual Review of Genetics. 1995, Vol. 29, p423-444. 22p.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 08/15/2000, Vol. 97 Issue 17, p9537, 6p, 2 Diagrams, 2 Charts, 1 Graph