Zobrazeno 1 - 10
of 1 376
pro vyhledávání: '"Golde Todd"'
Autor:
Levites, Yona, Dammer, Eric B., Ran, Yong, Tsering, Wangchen, Duong, Duc, Abreha, Measho, Gadhavi, Joshna, Lolo, Kiara, Trejo-Lopez, Jorge, Phillips, Jennifer, Iturbe, Andrea, Erquizi, Aya, Moore, Brenda D., Ryu, Danny, Natu, Aditya, Dillon, Kristy, Torrellas, Jose, Moran, Corey, Ladd, Thomas, Afroz, Farhana, Islam, Tariful, Jagirdar, Jaishree, Funk, Cory C., Robinson, Max, Rangaraju, Srikant, Borchelt, David R., Ertekin-Taner, Nilüfer, Kelly, Jeffrey W., Heppner, Frank L., Johnson, Erik C.B., McFarland, Karen, Levey, Allan I., Prokop, Stefan, Seyfried, Nicholas T., Golde, Todd E.
Publikováno v:
In Cell Reports Medicine 20 August 2024 5(8)
Akademický článek
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Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Verbeeck Christophe, Deng Qiudong, DeJesus-Hernandez Mariely, Taylor Georgia, Ceballos-Diaz Carolina, Kocerha Jannet, Golde Todd, Das Pritam, Rademakers Rosa, Dickson Dennis W, Kukar Thomas
Publikováno v:
Molecular Neurodegeneration, Vol 7, Iss 1, p 53 (2012)
Abstract Background Mutations in the gene encoding the RNA-binding protein fused in sarcoma (FUS) can cause familial and sporadic amyotrophic lateral sclerosis (ALS) and rarely frontotemproal dementia (FTD). FUS accumulates in neuronal cytoplasmic in
Externí odkaz:
https://doaj.org/article/adb84cf9be9b4d899a0ac297b0ee66eb
Autor:
Das Pritam, Verbeeck Christophe, Minter Lisa, Chakrabarty Paramita, Felsenstein Kevin, Kukar Thomas, Maharvi Ghulam, Fauq Abdul, Osborne Barbara A, Golde Todd E
Publikováno v:
Molecular Neurodegeneration, Vol 7, Iss 1, p 39 (2012)
Abstract Background Alzheimer’s disease (AD) is the leading cause of dementia among the elderly. Disease modifying therapies targeting Aβ that are in development have been proposed to be more effective if treatment was initiated prior to significa
Externí odkaz:
https://doaj.org/article/d7fec5cbc2c240f783f52f2f5c42dff2
Autor:
Chakrabarty Paramita, Tianbai Li, Herring Amanda, Ceballos-Diaz Carolina, Das Pritam, Golde Todd E
Publikováno v:
Molecular Neurodegeneration, Vol 7, Iss 1, p 36 (2012)
Abstract Background Pro-inflammatory stimuli, including cytokines like Interleukin-1β, Interleukin-6 and Interferon-γ, in the brain have been proposed to exacerbate existing Alzheimer’s disease (AD) neuropathology by increasing amyloidogenic proc
Externí odkaz:
https://doaj.org/article/babae6544d334406b3ee5a4cd449f3ff
Publikováno v:
Molecular Neurodegeneration, Vol 7, Iss 1, p 1 (2012)
Abstract Background The 5-lipoxygenase (5LO) enzymatic pathway is widely distributed within the central nervous system. Previous works showed that this protein is up-regulated in Alzheimer's disease (AD), and that its genetic absence results in a red
Externí odkaz:
https://doaj.org/article/94c7078db55d4472a7c103f2d766416e
Publikováno v:
Molecular Neurodegeneration, Vol 6, Iss 1, p 16 (2011)
Abstract Fibrillar amyloid β (fAβ) peptide is the major component of Aβ plaques in the brains of Alzheimer's disease (AD) patients. Inflammatory mediators have previously been proposed to be drivers of Aβ pathology in AD patients by increasing am
Externí odkaz:
https://doaj.org/article/ec1fbf4ae9ed43d2add6bb3b5484a8bf
Autor:
Golde Todd E, Das Pritam, Fauq Abdul, Borrelli Laura A, Thyssen Diana, Subramanian Meenakshi, Garcia-Alloza Monica, Hyman Bradley T, Bacskai Brian J
Publikováno v:
Molecular Neurodegeneration, Vol 4, Iss 1, p 19 (2009)
Abstract The γ-secretase complex is a major therapeutic target for the prevention and treatment of Alzheimer's disease. Previous studies have shown that treatment of young APP mice with specific inhibitors of γ-secretase prevented formation of new
Externí odkaz:
https://doaj.org/article/658faa2ba30b493abe9d7ad9adf7d410
Autor:
Petrucelli Leonard, Golde Todd E
Publikováno v:
Molecular Neurodegeneration, Vol 4, Iss 1, p 7 (2009)
Externí odkaz:
https://doaj.org/article/0a3571e0ff674613ab98a99abd6f6d70