Výsledky vyhledávání - "Goldbrunner RH"

Does delayed hospital admission of patients with aneurysmal subarachnoid haemorrhage translate into worse clinical outcome? Results of a single-centre propensity score analysis

Autor: Goertz, L, Pflaeging, M, Goldbrunner, RH, Brinker, G, Krischek, B

Publikováno v: 71. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 9. Joint Meeting mit der Japanischen Gesellschaft für Neurochirurgie; 20200621-20200624; sine loco [digital]; DOCV237 /20200626/

Objective: Early aneurysm embolization and standardized neurointensive care treatment within a neurovascular center are considered as key principles in the treatment of patients with aneurysmal subarachnoid haemorrhage (aSAH) in order to minimize sec

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Elective treatment of additional and recurrent aneurysms after previous subarachnoid haemorrhage – Are these patients at risk for complications and morbidity?

Autor: Goertz, L, Brinker, G, Hamisch, CA, Hof, M, Goldbrunner, RH, Krischek, B

Objective: Microsurgical clipping and endovascular coiling are safe and efficient treatment options for both ruptured and unruptured intracranial aneurysms. We hypothesized that complication and morbidity rates would be increased in patients with a p

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Symptomatic brain metastases in the elderly population – the risk and benefit of surgery in the context of systemic oncological treatment

Autor: Jünger, ST, Schödel, P, Proescholdt, M, Grau, S, Schebesch, KM, Doenitz, C, Rams, L, Brawanski, A, Kocher, M, Schulz, H, König, K, Goldbrunner, RH

Objective: For patients with brain metastases (BM) advanced age is considered a negative prognostic factor, especially since general condition frequently limited systemic treatment options. Due to lower toxicity, novel molecular agents comprise a sui

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The value of resection of symptomatic metastases from malignant melanoma in the spotlight of molecular treatment – a retrospective analysis

Autor: Hamisch, CA, Mauch, C, Proescholdt, M, Dietmaier, W, Wittersheim, M, Montesinos-Rongen, M, Brunn, A, Deckert, M, Kocher, M, Baues, C, Goldbrunner, RH, Ruge, MI, Grau, S

Objective: Prognosis for patients with metastatic melanoma has substantially changed due to novel medical and radiosurgical approaches. In this context, a cerebral metastectomy is rarely performed compared to other tumor entities, but is still indica

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The find-the-symbol test – a normative study comparing five parallel versions of a modified Bells neglect test designed for clinical monitoring of brain tumour patients

Autor: Schröter, C, Wagner, A, Kochs, S, Goldbrunner, RH, Weiß Lucas, C, NOA-19 Studiengruppe

Objective: The assessment of neurocognitive functions in brain tumour patients suffers from the limited availability of sensitive and validated intruments to detect even slight or moderate impairments. The Bells cancellation test is most widely used

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Performance of an advanced deep learning model in fully automated detection and segmentation of primary cerebral lymphoma using multiparametric MRI

Autor: Goertz, L, Borggrefe, J, Caldeira, LL, Hoyer, C, Goldbrunner, RH, Krischek, B, Laukamp, KR, Pennig, L

Objective: Magnetic resonance imaging (MRI) is the imaging modality of choice for detection of primary cerebral lymphoma. After initiating therapy, follow-up MRI scans are necessary to evaluate treatment response. An automated detection and segmentat

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Verbal learning memory testing for longitudinal assessment of German brain tumour patients

Autor: Klütsch, D, Jonas, K, Schröter, C, Goldbrunner, RH, Weiß Lucas, C, NOA-19 Studiengruppe

Objective: Due to its relative simplicity in comparison to other verbal learning memory tests (VLMT) the revised Hopkins VLMT (HVLMT-R) is used most often for the assessment of brain tumour patients. The German version of the HVLMT-R consists of a tr

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TERT and its binding protein – overexpression of GABPA/B in high-grade gliomas

Autor: Papazacharias, E, Kuhl, S, Goldbrunner, RH, Timmer, M

Objective: Enhanced expression of TERT in gliomas is a result of two hotspot mutations, C228T and C250T, at the promoter region. The GABP of the ETS family selectively binds at these positions respectively causing an activation of the promoter and ov

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Visceral membranectomy and preoperative midline shift are independent predictors of postoperative seizures in patients with chronic subdural haematoma

Autor: Goertz, L, Speier, J, Schulte, AP, Stavrinou, P, Goldbrunner, RH, Krischek, B, Timmer, M

Objective: Postoperative seizures represent a potential complication of surgical chronic subdural hematoma (cSDH) evacuation and may occur in 1 – 23% of cases. A risk factor analysis can help to identify patients that may benefit from anti-epilepti

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