Allantoin improves methionine-choline deficient diet-induced nonalcoholic steatohepatitis in mice through involvement in endoplasmic reticulum stress and hepatocytes apoptosis-related genes expressions

Autor: Komeili Movahhed, Tahereh, Moslehi, Azam, Golchoob, Mohammad, Ababzadeh, Shima

Publikováno v: Iranian Journal of Basic Medical Sciences, Vol 22, Iss 7, Pp 736-744 (2019)
Iranian Journal of Basic Medical Sciences

Objective(s): Non-alcoholic steatohepatitis (NASH) is defined by steatosis and inflammation in the hepatocytes, which can progress to cirrhosis and possibly hepatocellular carcinoma. However, current treatments are not entirely effective. Allantoin i

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http://ijbms.mums.ac.ir/article_13009_2f19f6202f8dedda2bc0f4cd4dc175a4.pdf