Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Golam T Saffi"'
Autor:
Golam T Saffi, Evan Tang, Sami Mamand, Subothan Inpanathan, Aaron Fountain, Leonardo Salmena, Roberto J Botelho
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0259313 (2021)
Lysosomes are terminal, degradative organelles of the endosomal pathway that undergo repeated fusion-fission cycles with themselves, endosomes, phagosomes, and autophagosomes. Lysosome number and size depends on balanced fusion and fission rates. Thu
Externí odkaz:
https://doaj.org/article/2e13202baa35471ea147821ba54376ff
Autor:
Anh Chu, Yeqi Yao, Golam T. Saffi, Ji Hyun Chung, Roberto J. Botelho, Miroslawa Glibowicka, Charles M. Deber, Morris F. Manolson
Publikováno v:
International Journal of Molecular Sciences
Volume 24
Issue 5
Pages: 4867
Volume 24
Issue 5
Pages: 4867
Vacuolar ATPases (V-ATPases) are multi-subunit ATP-dependent proton pumps necessary for cellular functions, including pH regulation and membrane fusion. The evidence suggests that the V-ATPase a-subunit’s interaction with the membrane signaling lip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965e4394b68a97508230747c04d530df
Autor:
Roberto Botelho, Leonardo Salmena, Aaron Fountain, Subothan Inpanathan, Sami Mamand, Evan Tang, Golam T. Saffi
Lysosomes are terminal, degradative organelles of the endosomal pathway that undergo repeated fusion-fission cycles with themselves, endosomes, phagosomes, and autophagosomes. Lysosome number and size depends on balanced fusion and fission rates. Thu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a6f5d64fc17211a8ab8551835fb1442
https://doi.org/10.32920/21982916.v1
https://doi.org/10.32920/21982916.v1
Autor:
Golam T. Saffi, Cheng An Wang, Emily M. Mangialardi, Jean Vacher, Roberto J. Botelho, Leonardo Salmena
Lysosome membranes contain diverse phosphoinositide (PtdIns) lipids that coordinate lysosome function and dynamics. The PtdIns repertoire on lysosomes is tightly regulated by the actions of diverse PtdIns kinases and phosphatases; however, specific r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dddd8871ec2c1fb356c1cfd1797278c
https://doi.org/10.32920/21982922.v1
https://doi.org/10.32920/21982922.v1
Autor:
Roberto J. Botelho, Krishna Chintaluri, Camilyn Clemenza, Brady D Goulden, Golam T. Saffi, Gerald R.V. Hammond, Emily Miraglia
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198454 (2018)
PLoS ONE
PLoS ONE
Phosphoinositide (PtdInsP) lipids recruit effector proteins to membranes to mediate a variety of functions including signal transduction and membrane trafficking. Each PtdInsP binds to a specific set of effectors through characteristic protein domain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::332543541626bf51739b01ab790cf97b
https://doi.org/10.32920/21982877
https://doi.org/10.32920/21982877
Lysosome membranes contain diverse phosphoinositide (PtdIns) lipids that co-ordinate lysosome function and dynamics. The PtdIns repertoire on lysosomes is tightly regulated by the action of diverse PtdIns kinases and phosphatases. Specific roles for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a0298f44f0a3ba9a62c6ab6eb0d42ef
https://doi.org/10.1101/2021.12.13.472440
https://doi.org/10.1101/2021.12.13.472440
Autor:
Emily Marie Mangialardi, Igor Jurisica, Leonardo Salmena, Daniel K.C. Lee, Meong Hi Son, John F. Woolley, Ruijuan He, Miki S. Gams, Ayesha Rashid, Jean Vacher, John E. Dick, Roberto J. Botelho, Martino Gabra, Erwin M. Schoof, Cynthia J. Guidos, Irakli Dzneladze, Gizem E. Genc, Max Kotlyar, Keyue Chen, Golam T. Saffi, Mark Minden, Stephanie Z. Xie
Signaling pathways that control vital features of leukemic stem cells including multipotency, self-renewal, clonal expansion and quiescence remain unclear. Emerging studies illustrate critical roles for lysosomes in hematopoietic and leukemic stem ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c069f4a36beb84cab3e5656a5d5597f2
https://doi.org/10.1101/2021.03.25.437029
https://doi.org/10.1101/2021.03.25.437029
Autor:
Roberto J. Botelho, Sami Mamand, Leonardo Salmena, Aaron Fountain, Subothan Inpanathan, Golam T. Saffi, Evan Tang
Publikováno v:
PLoS ONE, Vol 16, Iss 11, p e0259313 (2021)
PLoS ONE
PLoS ONE
Lysosomes are terminal, degradative organelles of the endosomal pathway that undergo repeated fusion-fission cycles with themselves, endosomes, phagosomes, and autophagosomes. Lysosome number and size depends on balanced fusion and fission rates. Thu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1fbd530ffef60763304198d27785e0f
https://doaj.org/article/2e13202baa35471ea147821ba54376ff
https://doaj.org/article/2e13202baa35471ea147821ba54376ff
Autor:
Golam T. Saffi, Evan Tang, Subothan Inpanathan, Sami Mammad, Aaron Fountain, Leonardo Salmena, Roberto J. Botelho
Lysosomes are terminal, degradative organelles of the endosomal pathway that undergo repeated fusion-fission cycles with themselves and other organelles like endosomes, phagosomes, and autophagosomes. Lysosome number, size and degradative flux depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4135770775cca30f46d1d39ffd95d6df
Autor:
Golam T. Saffi, Roberto J. Botelho
Publikováno v:
Trends in cell biology. 29(8)
Lysosomes are acidic and degradative organelles that receive and digest a plethora of molecular and particulate cargo delivered by endocytosis, autophagy, and phagocytosis. The mechanisms responsible for sorting, transporting, and ultimately deliveri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a31fadf9c16ea05e52823e1a373fb3f1
https://pubmed.ncbi.nlm.nih.gov/31171420
https://pubmed.ncbi.nlm.nih.gov/31171420