Zobrazeno 1 - 6 of 6 pro vyhledávání: '"Gokul Kandala"'
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Interactions between GIPC–APPL and GIPC–TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes
Autor: Sulochana Devi, Vijayasaradhi Setaluri, Rajendra Kedlaya, Tie Fu Liu, Gokul Kandala, Nityanand Maddodi
Publikováno v: Archives of Biochemistry and Biophysics. 508:227-233
By virtue of the presence of multiple protein–protein interaction and signaling domains, PDZ proteins play important roles in assembling protein complexes that participate in diverse cell biological processes. GIPC is a versatile PDZ protein that b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe929a3d10e7ecf1077122dcb8a53ed
https://doi.org/10.1016/j.abb.2011.01.021
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3
V600E BRAF mutation in pilocytic astrocytoma is associated with a more diffuse growth pattern but does not confer a more aggressive clinical behavior
Autor: Jean Lopategui, Sergei I. Bannykh, Gokul Kandala, Miriam A Nuno, James Mirocha
Publikováno v: Clinical neuropathology. 33(6)
Activation in mitogen activated protein kinase signaling pathway has recently been described as a predominant event in pilocytic astrocytoma (PA) and is commonly caused by constitutively active mutation in BRAF protein. Whereas PA of posterior fossa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::499d104eebef38e53d6a7a9f97b98e35
https://pubmed.ncbi.nlm.nih.gov/25066317
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4
PDZ Domain Protein GIPC Interacts with the Cytoplasmic Tail of Melanosomal Membrane Protein gp75 (Tyrosinase-related Protein-1)
Autor: Gokul Kandala, Tie Fu Liu, Vijayasaradhi Setaluri
Publikováno v: Journal of Biological Chemistry. 276:35768-35777
Tyrosinase and tyrosinase-related proteins (TRPs) are a family of melanosomal membrane proteins involved in mammalian pigmentation. Whereas the melanogenic functions of TRPs are localized in their amino-terminal domains that reside within the lumen o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e3bd1c29fd0c856d93273cf95daeb2
https://doi.org/10.1074/jbc.m103585200
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5
Molecular Characterization of a Novel Chromosomal Translocation in a Case of Acute Myeloid Leukemia Transformed From Myeloproliferative Neoplasm**
Autor: Chandrika Sreekantaiah, Dipti Gheewala, Craig Devoe, Nayyara Mahmood, Silvat Sheikh-Fayyaz, Xinmin Zhang, Gokul Kandala, Hua Guo, Judith Brody
Publikováno v: American Journal of Clinical Pathology. 144:A149-A149
Chromosomal band 11q13 has been reported to be a common site of aberrations in hematologic malignancies. However, only a few genes have been reported. We identified a novel t(11;14)(q13;q32) translocation in an acute myeloid leukemia (AML) case trans
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::11c0a9a38a231392f9a6c3ef841bdd62
https://doi.org/10.1093/ajcp/144.suppl2.149
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6
A novel gene product that couples TCR signaling to Fas(CD95) expression in activation-induced cell death
Autor: Soo Young Lee, Gokul Kandala, Chae Gyu Park, Yongwon Choi, Sang Yull Lee
Publikováno v: Immunity. 4(6)
Cross-linking the TCR in T cell hybridomas induces cell apoptosis following activation. This activation- induced apoptosis has been used as a model for clonal deletion of thymocytes or peripheral T cells. Anti-TCR-induced apoptosis of T cell hybridom
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e3192034101401e147ccb013a454802
https://pubmed.ncbi.nlm.nih.gov/8673705
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