Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Gokhul Kilaru"'
Autor:
Yasemin Onder, Isara Laothamatas, Stefano Berto, Katharina Sewart, Gokhul Kilaru, Bogdan Bordieanu, Jeremy J. Stubblefield, Genevieve Konopka, Prashant Mishra, Carla B. Green
Publikováno v:
iScience, Vol 19, Iss , Pp 83-92 (2019)
Summary: Fine-tuning of transcriptional responses can be critical for long-term outcomes in response to an environmental challenge. The circadian protein Nocturnin belongs to a family of proteins that include exonucleases, endonucleases, and phosphat
Externí odkaz:
https://doaj.org/article/9ad9f6c4ab354745b2182dc538214cf9
Autor:
Jeremy J. Stubblefield, Peng Gao, Gokhul Kilaru, Bilal Mukadam, Jeremy Terrien, Carla B. Green
Publikováno v:
Cell Reports, Vol 22, Iss 5, Pp 1225-1235 (2018)
Summary: The timing of food intake and nutrient utilization is critical to health and regulated partly by the circadian clock. Increased amplitude of circadian oscillations and metabolic output has been found to improve health in diabetic and obesity
Externí odkaz:
https://doaj.org/article/6ecd435b9f5f4e0b97aa824b76bda639
Autor:
Katie Schaukowitch, Austin L. Reese, Seung-Kyoon Kim, Gokhul Kilaru, Jae-Yeol Joo, Ege T. Kavalali, Tae-Kyung Kim
Publikováno v:
Cell Reports, Vol 18, Iss 6, Pp 1512-1526 (2017)
Homeostatic scaling allows neurons to maintain stable activity patterns by globally altering their synaptic strength in response to changing activity levels. Suppression of activity by the blocking of action potentials increases synaptic strength thr
Externí odkaz:
https://doaj.org/article/667cb3f9730c467da47d75d1ee2889df
Autor:
Chryssa Kanellopoulou, Timothy Gilpatrick, Gokhul Kilaru, Patrick Burr, Cuong K. Nguyen, Aaron Morawski, Michael J. Lenardo, Stefan A. Muljo
Publikováno v:
Stem Cell Reports, Vol 5, Iss 6, Pp 971-978 (2015)
Members of the miR-290 family are the most abundantly expressed microRNAs (miRNAs) in mouse embryonic stem cells (ESCs). They regulate aspects of differentiation, pluripotency, and proliferation of ESCs, but the molecular program that they control ha
Externí odkaz:
https://doaj.org/article/9fbba6fedbef453bbdf7719e0ce71e95
Autor:
Filipa Rijo-Ferreira, Inês Bento, John H. Abel, Maria M. Mota, Izabela Kornblum, Elizabeth B. Klerman, Gokhul Kilaru, Joseph S. Takahashi, Victoria A. Acosta-Rodríguez
Publikováno v:
Science
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works http://www.sciencemag.org/about/science-licenses-journal-article-reuseThis is an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dd91c9014eb011aa92143eff6659b8b
https://doi.org/10.1126/science.aba2658
https://doi.org/10.1126/science.aba2658
Autor:
Carla B. Green, Yasemin Onder, Gokhul Kilaru, Isara Laothamatas, Prashant Mishra, Jeremy J. Stubblefield, Genevieve Konopka, Katharina Sewart, Bogdan Bordieanu, Stefano Berto
Publikováno v:
iScience
iScience, Vol 19, Iss, Pp 83-92 (2019)
iScience, Vol 19, Iss, Pp 83-92 (2019)
Summary Fine-tuning of transcriptional responses can be critical for long-term outcomes in response to an environmental challenge. The circadian protein Nocturnin belongs to a family of proteins that include exonucleases, endonucleases, and phosphata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::659959373db99bb33b862298b018140f
http://europepmc.org/articles/PMC6664146
http://europepmc.org/articles/PMC6664146
Autor:
Dahun Um, Seung Kyoon Kim, Gokhul Kilaru, Kimberly M. Huber, Tae Kyung Kim, Jongmin Park, Cheng Ming Chiang, Xihui Liu, Keunsoo Kang, Mingon Kang
Publikováno v:
Science Advances
The coordination of BET family proteins is a feature of the gene regulatory network underlying memory behavior and FXS.
Bromodomain and extraterminal proteins (BET) are epigenetic readers that play critical roles in gene regulation. Pharmacologi
Bromodomain and extraterminal proteins (BET) are epigenetic readers that play critical roles in gene regulation. Pharmacologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfc9f436a206b95e16517705d1a60e7c
http://europepmc.org/articles/PMC8133748
http://europepmc.org/articles/PMC8133748
Autor:
Joseph S. Takahashi, Genevieve Konopka, Gokhul Kilaru, Yan Li, Kimberly H. Cox, Yongli Shan, Shuzhang Yang, Stefano Berto, Guang-Zhong Wang, Seung Hee Yoo
Publikováno v:
eLife, Vol 9 (2020)
eLife
eLife
Circadian oscillations are generated via transcriptional-translational negative feedback loops. However, individual cells from fibroblast cell lines have heterogeneous rhythms, oscillating independently and with different period lengths. Here we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5035049b540286875e52b249ea3e8805
https://doi.org/10.7554/elife.54186
https://doi.org/10.7554/elife.54186
Autor:
Yan Li, Yongli Shan, Guang-Zhong Wang, Shuzhang Yang, Seung Hee Yoo, Kimberly H. Cox, Stefano Berto, Joseph S. Takahashi, Gokhul Kilaru, Genevieve Konopka
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::198a8fa6945e6e529fff5dfa3b403740
https://doi.org/10.7554/elife.54186.sa2
https://doi.org/10.7554/elife.54186.sa2
Autor:
Jianhui Wang, Miao Tang, Jennifer A. Mohawk, Gokhul Kilaru, Diantha La Vine, Eva Marie Y. Moresco, Jin Huk Choi, Bruce Beutler, Lei Sun, Sara Hildebrand, Victoria A. Acosta-Rodríguez, Zhengfan Jiang, Xiaoming Zhan, Xiaohong Li, Kuan Wen Wang, Joseph S. Takahashi, Jiexia Quan, Xin Du, Michael Berger, Anne R. Murray, Lindsay Scott
Publikováno v:
Journal of Experimental Medicine. 214:3263-3277
Transcriptional regulation of numerous interferon-regulated genes, including Toll-like receptor 3 (Tlr3), which encodes an innate immune sensor of viral double-stranded RNA, depends on the interferon regulatory factor 1 (IRF1) and IRF2 transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af9d0852e26877d95eef82c85390d3e9
https://doi.org/10.1084/jem.20161630
https://doi.org/10.1084/jem.20161630