Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Gokhan M. Mutlu"'
Autor:
Rengul Cetin‐Atalay, Angelo Y. Meliton, Kaitlyn A. Sun, Parker S. Woods, Ying‐Jie Peng, Yun Fang, Robert B. Hamanaka, Nanduri R. Prabhakar, Gokhan M. Mutlu
Publikováno v:
The FASEB Journal. 36
Autor:
William W Wheaton, Samuel E Weinberg, Robert B Hamanaka, Saul Soberanes, Lucas B Sullivan, Elena Anso, Andrea Glasauer, Eric Dufour, Gokhan M Mutlu, GR Scott Budigner, Navdeep S Chandel
Publikováno v:
eLife, Vol 3 (2014)
Recent epidemiological and laboratory-based studies suggest that the anti-diabetic drug metformin prevents cancer progression. How metformin diminishes tumor growth is not fully understood. In this study, we report that in human cancer cells, metform
Externí odkaz:
https://doaj.org/article/ab1cc35411e44f338acc368baee076d9
Autor:
Gokhan M. Mutlu
Publikováno v:
Güncel Göğüs Hastalıkları Serisi. 6
Autor:
Rengul Cetin-Atalay, Angelo Y. Meliton, Kaitlyn A. Sun, Mariel E. Glass, Parker S. Woods, Ying-Jie Peng, Yun Fang, Robert B. Hamanaka, Nanduri R. Prabhakar, Gökhan M. Mutlu
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Obstructive sleep apnea (OSA) is an independent risk factor for cardiovascular disease. While intermittent hypoxia (IH) and catecholamine release play an important role in this increased risk, the mechanisms are incompletely understood. We h
Externí odkaz:
https://doaj.org/article/78a6903cbc554691bb1bab10ab7d2575
Autor:
Luisa Morales-Nebreda, Mesut Eren, Saul Soberanes, Recep Nigdelioglu, Micah Rogel, Monica Chi, Takugo Cho, Robert Hamanaka, Douglas E Vaughan, GR Scott Budinger, Gokhan M Mutlu
Publikováno v:
Circulation. 130
Rationale: Influenza A virus (IAV) is the leading cause of death from an infectious cause and ranks 8th in the list of attributable annual mortality in the United States. Currently available antiviral treatments are limited and may become ineffective
Autor:
M. Fatih Abasıyanık, Krysta Wolfe, Hoang Van Phan, Jing Lin, Bharathi Laxman, Steven R. White, Philip A. Verhoef, Gökhan M. Mutlu, Bhakti Patel, Savaş Tay
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Ultrasensitive methods for detection of biomarkers for infectious disease are needed for diagnosing, monitoring and targeting treatment. Here the authors develop a digital assay for inflammatory markers, bacterial DNA and antibotic-resistance genes a
Externí odkaz:
https://doaj.org/article/b5d1efb0f6d045c4b3695d27b42dc37d
Autor:
Rengul Cetin-Atalay, Angelo Y. Meliton, David Wu, Parker S. Woods, Kaitlyn A. Sun, Ying-Jie Peng, Jayasri Nanduri, Xiaoyu Su, Yun Fang, Robert B. Hamanaka, Nanduri Prabhakar, Gökhan M. Mutlu
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Obstructive sleep apnea (OSA) is a common breathing disorder affecting a significant percentage of the adult population. OSA is an independent risk factor for cardiovascular disease (CVD); however, the underlying mechanisms are not completely underst
Externí odkaz:
https://doaj.org/article/b9c692b18c724b9f9e6edc007e2175e8
Autor:
Eleanor B. Reed, Shawn Ard, Jennifer La, Chan Young Park, Laura Culligan, Jeffrey J. Fredberg, Larisa V. Smolyaninova, Sergei N. Orlov, Bohao Chen, Robert Guzy, Gökhan M. Mutlu, Nickolai O. Dulin
Publikováno v:
Respiratory Research, Vol 20, Iss 1, Pp 1-7 (2019)
Abstract Background Pulmonary fibrosis is a progressive disease characterized by structural distortion of the lungs. Transforming growth factor-beta (TGF-beta) is a key cytokine implicated in the pathogenesis of pulmonary fibrosis. TGF-beta-induced m
Externí odkaz:
https://doaj.org/article/c1a1ea1174e447d89eb70f916718c3b8
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Chronic obstructive pulmonary disease (COPD) is a severe respiratory disease with high morbidity and mortality, representing the third leading cause of death worldwide. Traditional risk factors for COPD include aging, genetic predisposition, cigarett
Externí odkaz:
https://doaj.org/article/fe116a0a93af4cfa81dfdfb9bd374b42
Autor:
Lucas M. Kimmig, David Wu, Matthew Gold, Natasha N. Pettit, David Pitrak, Jeffrey Mueller, Aliya N. Husain, Ece A. Mutlu, Gökhan M. Mutlu
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Background: Anti-inflammatory therapies such as IL-6 inhibition have been proposed for COVID-19 in a vacuum of evidence-based treatment. However, abrogating the inflammatory response in infectious diseases may impair a desired host response and pre-d
Externí odkaz:
https://doaj.org/article/4909ef0b306f4a6bb05e1b479c9f701a