Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Goker Arpag"'
Publikováno v:
eLife, Vol 10 (2021)
Sjögren’s syndrome nuclear autoantigen-1 (SSNA1/NA14) is a microtubule-associated protein with important functions in cilia, dividing cells, and developing neurons. However, the direct effects of SSNA1 on microtubules are not known. We employed in
Externí odkaz:
https://doaj.org/article/d2cf224b3ca1440bb9f2d0130536c53f
Autor:
Kathryn P Trogden, Justin Lee, Kai M Bracey, Kung-Hsien Ho, Hudson McKinney, Xiaodong Zhu, Goker Arpag, Thomas G Folland, Anna B Osipovich, Mark A Magnuson, Marija Zanic, Guoqiang Gu, William R Holmes, Irina Kaverina
Publikováno v:
eLife, Vol 10 (2021)
Heterogeneity of glucose-stimulated insulin secretion (GSIS) in pancreatic islets is physiologically important but poorly understood. Here, we utilize mouse islets to determine how microtubules (MTs) affect secretion toward the vascular extracellular
Externí odkaz:
https://doaj.org/article/9506901faa9e40da9a5c9f740c2f02ad
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Sjögren’s syndrome nuclear autoantigen-1 (SSNA1/NA14) is a microtubule-associated protein with important functions in cilia, dividing cells, and developing neurons. However, the direct effects of SSNA1 on microtubules are not known. We employed in
Autor:
Thomas G. Folland, Kathryn P Trogden, Goker Arpag, Marija Zanic, Kung-Hsien Ho, Kai M. Bracey, Guoqiang Gu, Anna B. Osipovich, Justin Lee, Hudson McKinney, William R. Holmes, Irina Kaverina, Mark A. Magnuson, Xiaodong Zhu
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Heterogeneity of glucose-stimulated insulin secretion (GSIS) in pancreatic islets is physiologically important but poorly understood. Here, we utilize mouse islets to determine how microtubules (MTs) affect secretion toward the vascular extracellular
Autor:
Kathryn P Trogden, Justin Lee, Kung-Hsien Ho, Marija Zanic, Xiaodong Zhu, Anna B. Osipovich, Hudson McKinney, Irina Kaverina, William R. Holmes, Guoqiang Gu, Mark A. Magnuson, Goker Arpag, Kai M. Bracey, Thomas G. Folland
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecf5c1d14d3280fe1378064a66a760fb
https://doi.org/10.7554/elife.59912.sa2
https://doi.org/10.7554/elife.59912.sa2
Autor:
Marija Podolski, Ryoma Ohi, Veronica Farmer, Nicole Rodgers, Claire E. Strothman, Goker Arpag, Stephen R. Norris, Marija Zanic
Publikováno v:
The Journal of Cell Biology
Linda Wordeman discusses work from Strothman et al. that sheds new light on the differences between plus- and minus-end microtubule dynamics.
Microtubule minus ends are inherently more stable than plus ends despite the fact that free tubulin ass
Microtubule minus ends are inherently more stable than plus ends despite the fact that free tubulin ass
Publikováno v:
The Journal of cell biology. 220(10)
The GTP-tubulin cap is widely accepted to protect microtubules against catastrophe. The GTP-cap size is thought to increase with the microtubule growth rate, presumably endowing fast-growing microtubules with enhanced stability. It is unknown what GT
Autor:
William R. Holmes, Xiaodong Zhu, Kathryn P Trogden, Anna B. Osipovich, Marija Zanic, Thomas G. Folland, Irina Kaverina, Hudson McKinney, Guoqiang Gu, Goker Arpag, Mark A. Magnuson
Heterogeneity of glucose-stimulated insulin secretion (GSIS) in pancreatic islets is physiologically important but poorly understood. Here, we utilize whole mouse islets to determine how microtubules affect secretion toward the vascular extracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4f2fb903c94f9bf56fcc322c32f9a93
https://doi.org/10.1101/2020.06.12.148668
https://doi.org/10.1101/2020.06.12.148668
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Treadmilling is a complex behavior of active polymers characterized by polymerization at one polymer end and simultaneous depolymerization at the other end. Treadmilling is an essential feature of cytoskeletal filaments driving actin-bas