Výsledky vyhledávání - "Gokce Celikyapi Erdem"

Akademický článek

Alternatively spliced MEFV transcript lacking exon 2 and its protein isoform pyrin-2d implies an epigenetic regulation of the gene in inflammatory cell culture models

Autor: Gokce Celikyapi Erdem, Sule Erdemir, Irem Abaci, Asli K. Kirectepe Aydin, Elif Everest, Eda Tahir Turanli

Publikováno v: Genetics and Molecular Biology, Vol 40, Iss 3, Pp 688-697 (2017)

Abstract The function of gene body DNA methylation in alternative splicing, and its relation to disease pathogenesis is not fully elucidated. The gene for familial Mediterranean fever (MEFV) encodes the pyrin protein and contains a 998 bp CpG island,

Externí odkaz: https://doaj.org/article/9806ab04d25b4e79b525488b748e380b

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Investigation of neuro-inflammatory parameters in a cuprizone induced mouse model of multiple sclerosis

Autor: Gökhan Terzioğlu, Timucin Avsar, Gokce Celikyapi Erdem, Eda Tahir Turanli

Publikováno v: Turkish Journal of Biology

Cuprizone, copper chelator, treatment of mouse is a toxic model of multiple sclerosis (MS) in which oligodendrocyte death, demyelination and remyelination can be observed. Understanding T and B cell subset as well as their cytokines involved in MS pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7abb0dbeeb36463686fd3a04fa6b0add
https://pubmed.ncbi.nlm.nih.gov/34803461

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Alternatively spliced MEFV transcript lacking exon 2 and its protein isoform pyrin-2d implies an epigenetic regulation of the gene in inflammatory cell culture models

Autor: Asli Kirectepe Aydin, Sule Erdemir, Eda Tahir Turanli, Elif Everest, Gokce Celikyapi Erdem, Irem Abaci

Publikováno v: Genetics and Molecular Biology, Vol 40, Iss 3, Pp 688-697 (2017)
Genetics and Molecular Biology, Volume: 40, Issue: 3, Pages: 688-697, Published: 31 AUG 2017
Genetics and Molecular Biology v.40 n.3 2017
Genetics and Molecular Biology
Sociedade Brasileira de Genética (SBG)
instacron:SBG

The function of gene body DNA methylation in alternative splicing, and its relation to disease pathogenesis is not fully elucidated. The gene for familial Mediterranean fever (MEFV) encodes the pyrin protein and contains a 998 bp CpG island, covering

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd75f3449905b111a8cb1af39f4754d
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1415-47572017000400688&lng=en&tlng=en

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Analysis of MEFV exon methylation and expression patterns in familial Mediterranean fever

Autor: Ozgur Kasapcopur, Gulen Hatemi, Eda Tahir Turanli, Gokce Celikyapi Erdem, Asli K Kirectepe, Huri Ozdogan, Nil Arisoy

Publikováno v: BMC Medical Genetics
BMC Medical Genetics, Vol 12, Iss 1, p 105 (2011)

Background MEFV mutations and decreased expression level of the gene are related to FMF pathology. DNA methylation at CpG islands is a well-known mechanism for transcriptional silencing. MEFV has a CpG island, spanning a part of the first intron and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75f852a494133d9102b45dead2f6cb2c
http://europepmc.org/articles/PMC3175150

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