Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Goichi Yanai"'
Publikováno v:
Regenerative Therapy, Vol 7, Iss C, Pp 52-60 (2017)
Introduction: Formation of cell spheres is an important procedure in biomedical research. A large number of high-quality cell spheres of uniform size and shape are required for basic studies and therapeutic applications. Conventional approaches, incl
Externí odkaz:
https://doaj.org/article/67dde4838f6648b4aa93415ae4ae9f4d
Autor:
Goichi Yanai, Takashi Hayashi, Qi Zhi, Kai-Chiang Yang, Yasumasa Shirouzu, Takashi Shimabukuro, Akihito Hiura, Kazutomo Inoue, Shoichiro Sumi
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64499 (2013)
Islet transplantation is a minimally invasive treatment for severe diabetes. However, it often requires multiple donors to accomplish insulin-independence and the long-term results are not yet satisfying. Therefore, novel ways to overcome these probl
Externí odkaz:
https://doaj.org/article/9120ab3ec79c41cc87e54778fdedc7f3
Autor:
Zhi Qi, Chizuru Yamamoto, Naomi Imori, Ayano Kinukawa, Kai-Chiang Yang, Goichi Yanai, Etsuko Ikenoue, Yanna Shen, Yasumasa Shirouzu, Akihito Hiura, Kazutomo Inoue, Shoichiro Sumi M.D., Ph.D.
Publikováno v:
Cell Transplantation, Vol 21 (2012)
Islet transplantation has shown great success in the treatment of type 1 diabetes since the Edmonton protocol was established. However, it still has two major problems to overcome: the lack of organ donors and the side effects of immunosuppression. E
Externí odkaz:
https://doaj.org/article/c8ec3c77ca7b4471aa9275326d711e97
Publikováno v:
Regenerative Therapy, Vol 7, Iss C, Pp 52-60 (2017)
Introduction: Formation of cell spheres is an important procedure in biomedical research. A large number of high-quality cell spheres of uniform size and shape are required for basic studies and therapeutic applications. Conventional approaches, incl
Publikováno v:
Journal of Biomedical Materials Research Part B: Applied Biomaterials. 106:1809-1817
Proinflammatory cytokines and reactive oxygen species (ROS) are known to be involved in the initiation and progression of osteoarthritis (OA). New evidence clarifying the correlation between ROS and inflammation has indicated that oxidative stress ca
Publikováno v:
Cellular Reprogramming. 18:171-186
Nodal/activin signaling is indispensable for embryonic development. We examined what activin does to the embryoid bodies (EBs) produced from mouse embryonic stem cells (mESCs) expressing an epiblast marker. The EBs were produced by culturing mESCs by
Autor:
Kai Chiang Yang, Shoichiro Sumi, Masako Kawagoe, Priyadarshini Canning, Sin Yu Yang, Goichi Yanai, Yoshio Satou
Publikováno v:
Biotechnology and bioengineering. 115(9)
Transplantation of encapsulated porcine islets is proposed to treat type 1 diabetes. However, the envelopment of fibrous tissue and the infiltration of immune cells impair islet function and eventually cause implant failure. It is known that hemodial
Publikováno v:
Journal of biomedical materials research. Part B, Applied biomaterials. 106(5)
Proinflammatory cytokines and reactive oxygen species (ROS) are known to be involved in the initiation and progression of osteoarthritis (OA). New evidence clarifying the correlation between ROS and inflammation has indicated that oxidative stress ca
Autor:
Goichi Yanai, Hsuan-Shu Lee, Shoichiro Sumi, Dai Hua Lu, Yasumasa Shirouza, Zhi Qi, Kai Chiang Yang
Publikováno v:
Process Biochemistry. 46:1853-1860
The intracellular contact between pancreatic β-cells plays an important role in functional insulin secretion. We propose cell coupling may regulate glucose-stimulated insulin gene expression. MIN-6, a murine β-cell line, was cultured on the Lipidur
Autor:
Shoichiro Sumi, Yasumasa Shirouzu, Akihito Hiura, Kai Chiang Yang, Yanna Shen, Goichi Yanai, Zhi Qi
Publikováno v:
Biomaterials. 31:4026-4031
Islet transplantation is a method for the treatment of type 1 diabetes mellitus (DM) and has been widely performed around the world. The long-term cryopreservation of islets shows many advantages in the field of islet transplantation. Previous studie