Defining the structural basis for human alloantibody binding to human leukocyte antigen allele HLA-A*11:01.

Autor: Gu Y; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; NUS Graduate School for Integrative Sciences and Engineering (NGS), National University of Singapore, Singapore, Singapore.; Immunology Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Wong YH; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Singapore, Singapore., Liew CW; NTU Institute of Structural Biology, Nanyang Technological University, Singapore, Singapore., Chan CEZ; DSO National Laboratories, Singapore, Singapore., Murali TM; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Immunology Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Yap J; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Immunology Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Too CT; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Immunology Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Purushotorman K; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Immunology Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Hamidinia M; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Immunology Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., El Sahili A; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.; NTU Institute of Structural Biology, Nanyang Technological University, Singapore, Singapore., Goh ATH; National University Centre for Organ Transplantation (NUCOT), National University Hospital, Singapore, Singapore., Teo RZC; National University Centre for Organ Transplantation (NUCOT), National University Hospital, Singapore, Singapore., Wood KJ; Transplantation Research Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, Oxford, UK., Hanson BJ; DSO National Laboratories, Singapore, Singapore., Gascoigne NRJ; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; NUS Graduate School for Integrative Sciences and Engineering (NGS), National University of Singapore, Singapore, Singapore.; Immunology Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lescar J; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore. Julien@ntu.edu.sg.; NTU Institute of Structural Biology, Nanyang Technological University, Singapore, Singapore. Julien@ntu.edu.sg., Vathsala A; National University Centre for Organ Transplantation (NUCOT), National University Hospital, Singapore, Singapore. mdcva@nus.edu.sg.; Division of Nephrology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. mdcva@nus.edu.sg., MacAry PA; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. micpam@nus.edu.sg.; NUS Graduate School for Integrative Sciences and Engineering (NGS), National University of Singapore, Singapore, Singapore. micpam@nus.edu.sg.; Immunology Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. micpam@nus.edu.sg.

Publikováno v: Nature communications [Nat Commun] 2019 Feb 21; Vol. 10 (1), pp. 893. Date of Electronic Publication: 2019 Feb 21.

La transplantation rénale

Autor: LEGENDRE Christophe

La transplantation rénale est la greffe la plus courante et la plus fiable. Elle est l'une des illustrations les plus emblématiques des progrès médicaux réalisés au cours des cinquante dernières années. Cependant d'importantes difficultés pe