Zobrazeno 1 - 10 of 251 pro vyhledávání: '"Gogliotti RG"'
1
Akademický článek
Site-blocking antisense oligonucleotides as a mechanism to fine-tune MeCP2 expression.
Autor: Vanderplow AM; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, Illinois 60153, USA., Dodis GE; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, Illinois 60153, USA., Rhee Y; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, Illinois 60153, USA., Cikowski JJ; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, Illinois 60153, USA.; Department of Pharmacology, University of Michigan, Ann Arbor, Michigan 48109, USA., Gonzalez S; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, Illinois 60153, USA., Smith ML; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, Illinois 60153, USA., Gogliotti RG; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, Illinois 60153, USA rgogliotti@luc.edu.
Publikováno v: RNA (New York, N.Y.) [RNA] 2024 Nov 18; Vol. 30 (12), pp. 1554-1571. Date of Electronic Publication: 2024 Nov 18.
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2
Akademický článek
MeCP2 gene therapy ameliorates disease phenotype in mouse model for Pitt Hopkins syndrome.
Autor: Dennys CN; Center for Gene Therapy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA., Vermudez SAD; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA., Deacon RJM; Department of Genetics, Institute of Ecology and Biodiversity, Faculty of Science, University of Chile, Chile., Sierra-Delgado JA; Center for Gene Therapy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA., Rich K; Center for Gene Therapy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA., Zhang X; Center for Gene Therapy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA., Buch A; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA., Weiss K; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA., Moxley Y; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA., Rajpal H; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA., Espinoza FD; Faculty of Medicine, Universidad Católica de la Santísima Concepción, Concepción, 4090541, Chile., Powers S; Center for Gene Therapy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA., Ávila AS; Faculty of Medicine, Universidad Católica de la Santísima Concepción, Concepción, 4090541, Chile., Gogliotti RG; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, IL 60153, USA., Cogram P; Department of Genetics, Institute of Ecology and Biodiversity, Faculty of Science, University of Chile, Chile., Niswender CM; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN 37232, USA; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN 37232, USA; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37232, USA; Vanderbilt Kennedy Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA., Meyer KC; Center for Gene Therapy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, USA; Department of Pediatrics, The Ohio State University Medical Center, Columbus, OH, USA; Department of Neuroscience, The Ohio State University Wexner Medical Center, Columbus, OH, USA. Electronic address: km2dq@missouri.edu.
Publikováno v: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics [Neurotherapeutics] 2024 Sep; Vol. 21 (5), pp. e00376. Date of Electronic Publication: 2024 Jun 14.
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3
Potentiation of the M 1 muscarinic acetylcholine receptor normalizes neuronal activation patterns and improves apnea severity in Mecp2 +/- mice.
Autor: Smith M, Dodis GE, Vanderplow AM, Gonzalez S, Rhee Y, Gogliotti RG
Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Apr 17. Date of Electronic Publication: 2024 Apr 17.
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4
Akademický článek
Optimized Administration of the M 4 PAM VU0467154 Demonstrates Broad Efficacy, but Limited Effective Concentrations in Mecp2 +/ - Mice.
Autor: Cikowski J; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, Illinois 60153, United States.; Edward Hines Jr. VA Hospital, Hines, Illinois 60141, United States., Holt C; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, Illinois 60153, United States.; Edward Hines Jr. VA Hospital, Hines, Illinois 60141, United States., Arthur B; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee 37232, United States.; Vanderbilt Kennedy Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States., Smith M; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, Illinois 60153, United States.; Edward Hines Jr. VA Hospital, Hines, Illinois 60141, United States., Gonzalez S; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, Illinois 60153, United States.; Edward Hines Jr. VA Hospital, Hines, Illinois 60141, United States., Lindsley CW; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee 37232, United States.; Vanderbilt Kennedy Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States.; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States.; Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37232, United States., Niswender CM; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee 37232, United States.; Vanderbilt Kennedy Center, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States.; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee 37232, United States.; Vanderbilt Brain Institute, Vanderbilt University, Nashville, Tennessee 37232, United States., Gogliotti RG; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, Illinois 60153, United States.; Edward Hines Jr. VA Hospital, Hines, Illinois 60141, United States.; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee 37232, United States.
Publikováno v: ACS chemical neuroscience [ACS Chem Neurosci] 2022 Jul 06; Vol. 13 (13), pp. 1891-1901. Date of Electronic Publication: 2022 Jun 07.
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5
Akademický článek
Clinical and Preclinical Evidence for M 1 Muscarinic Acetylcholine Receptor Potentiation as a Therapeutic Approach for Rett Syndrome.
Autor: Smith M; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, IL, 60153, USA.; Edward Hines Jr. VA Hospital, Hines, IL, 60141, USA., Arthur B; Department of Pharmacology, Vanderbilt University, Nashville, TN, 37232, USA.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Kennedy Center, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Cikowski J; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, IL, 60153, USA.; Edward Hines Jr. VA Hospital, Hines, IL, 60141, USA., Holt C; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, IL, 60153, USA.; Edward Hines Jr. VA Hospital, Hines, IL, 60141, USA., Gonzalez S; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, IL, 60153, USA.; Edward Hines Jr. VA Hospital, Hines, IL, 60141, USA., Fisher NM; Department of Pharmacology, Vanderbilt University, Nashville, TN, 37232, USA.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Kennedy Center, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Vermudez SAD; Department of Pharmacology, Vanderbilt University, Nashville, TN, 37232, USA.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Kennedy Center, Vanderbilt University Medical Center, Nashville, TN, 37232, USA., Lindsley CW; Department of Pharmacology, Vanderbilt University, Nashville, TN, 37232, USA.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Kennedy Center, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN, 37232, USA.; Department of Chemistry, Vanderbilt University, Nashville, TN, 37232, USA., Niswender CM; Department of Pharmacology, Vanderbilt University, Nashville, TN, 37232, USA.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Kennedy Center, Vanderbilt University Medical Center, Nashville, TN, 37232, USA.; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN, 37232, USA.; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, 37232, USA., Gogliotti RG; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, IL, 60153, USA. rgogliotti@luc.edu.; Edward Hines Jr. VA Hospital, Hines, IL, 60141, USA. rgogliotti@luc.edu.; Department of Pharmacology, Vanderbilt University, Nashville, TN, 37232, USA. rgogliotti@luc.edu.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN, 37232, USA. rgogliotti@luc.edu.
Publikováno v: Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics [Neurotherapeutics] 2022 Jul; Vol. 19 (4), pp. 1340-1352. Date of Electronic Publication: 2022 Jun 07.
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6
Akademický článek
Exploration of group II metabotropic glutamate receptor modulation in mouse models of Rett syndrome and MECP2 Duplication syndrome.
Autor: Vermudez SAD; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN, 37232, USA., Buch A; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN, 37232, USA., Weiss K; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN, 37232, USA., Gogliotti RG; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, IL, 60660, USA., Niswender CM; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, TN, 37232, USA; Vanderbilt Kennedy Center, Vanderbilt University, Nashville, TN, 37232, USA; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, TN, 37232, USA; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN, 37232, USA. Electronic address: Colleen.niswender@vanderbilt.edu.
Publikováno v: Neuropharmacology [Neuropharmacology] 2022 May 15; Vol. 209, pp. 109022. Date of Electronic Publication: 2022 Mar 03.
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7
Akademický článek
Profiling beneficial and potential adverse effects of MeCP2 overexpression in a hypomorphic Rett syndrome mouse model.
Autor: Vermudez SAD; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA., Gogliotti RG; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Chicago, Illinois, USA., Arthur B; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA., Buch A; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA., Morales C; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA., Moxley Y; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA., Rajpal H; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA., Conn PJ; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt Kennedy Center, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee, USA., Niswender CM; Department of Pharmacology and Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt Kennedy Center, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee, USA.
Publikováno v: Genes, brain, and behavior [Genes Brain Behav] 2022 Jan; Vol. 21 (1), pp. e12752. Date of Electronic Publication: 2021 May 28.
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8
Akademický článek
Activating mGlu 3 Metabotropic Glutamate Receptors Rescues Schizophrenia-like Cognitive Deficits Through Metaplastic Adaptations Within the Hippocampus.
Autor: Dogra S; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee., Stansley BJ; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee., Xiang Z; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee., Qian W; Vanderbilt University, Nashville, Tennessee., Gogliotti RG; Molecular Pharmacology and Neuroscience Department, Loyola University Chicago, Maywood, Illinois., Nicoletti F; IRCCS Neuromed, Pozzilli, Italy; Department of Physiology and Pharmacology, Sapienza University of Rome, Rome, Italy., Lindsley CW; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee; Department of Chemistry, Vanderbilt University, Nashville, Tennessee; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee; Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, Tennessee., Niswender CM; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee; Vanderbilt Kennedy Center, Vanderbilt University, Nashville, Tennessee., Joffe ME; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee; Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, Tennessee. Electronic address: max.joffe@vanderbilt.edu., Conn PJ; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee; Vanderbilt Center for Addiction Research, Vanderbilt University, Nashville, Tennessee; Vanderbilt Kennedy Center, Vanderbilt University, Nashville, Tennessee. Electronic address: jeff.conn@vanderbilt.edu.
Publikováno v: Biological psychiatry [Biol Psychiatry] 2021 Sep 15; Vol. 90 (6), pp. 385-398. Date of Electronic Publication: 2021 Mar 06.
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9
Akademický článek
Effect of the mRNA decapping enzyme scavenger (DCPS) inhibitor RG3039 on glioblastoma.
Autor: Duan, Hao1 (AUTHOR), Xie, Yuan1 (AUTHOR), Wu, Suwen2 (AUTHOR), Zhao, Guangyin3 (AUTHOR), Zeng, Zhen4 (AUTHOR), Hu, Hongrong1 (AUTHOR), Yu, Yanjiao1 (AUTHOR), Hu, Wanming5 (AUTHOR), Yang, Yuanzhong5 (AUTHOR), Chen, Yukun6 (AUTHOR), Xie, Haoqun1 (AUTHOR), Chen, Zexin7 (AUTHOR), Zhang, Gao8 (AUTHOR), Flaherty, Keith T.9 (AUTHOR), Hu, Shanshan10 (AUTHOR), Xu, Haineng11 (AUTHOR) haineng@pennmedicine.UPenn.edu, Ma, Wenjuan12 (AUTHOR) mawenj@sysucc.org.cn, Mou, Yonggao1 (AUTHOR) mouyg@sysucc.org.cn
Publikováno v: Journal of Translational Medicine. 9/30/2024, Vol. 22 Issue 1, p1-18. 18p.
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10
Akademický článek
A GRM7 mutation associated with developmental delay reduces mGlu7 expression and produces neurological phenotypes.
Autor: Fisher NM; Department of Pharmacology and.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA., AlHashim A; King Fahad Medical City, Riyadh, Saudi Arabia., Buch AB; Department of Pharmacology and.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA., Badivuku H; Department of Pharmacology and.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA., Samman MM; King Fahad Medical City, Riyadh, Saudi Arabia., Weiss KM; Department of Pharmacology and.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA., Cestero GI; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, USA., Does MD; Department of Biomedical Engineering, Vanderbilt University, Nashville, Tennessee, USA., Rook JM; Department of Pharmacology and.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA., Lindsley CW; Department of Pharmacology and.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA.; Department of Chemistry and.; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee, USA., Conn PJ; Department of Pharmacology and.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt Kennedy Center, Vanderbilt University Medical Center, Nashville, Tennessee USA., Gogliotti RG; Department of Pharmacology and.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA.; Department of Molecular Pharmacology and Neuroscience, Loyola University Chicago, Maywood, Illinois, USA., Niswender CM; Department of Pharmacology and.; Warren Center for Neuroscience Drug Discovery, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt Institute of Chemical Biology, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt Kennedy Center, Vanderbilt University Medical Center, Nashville, Tennessee USA.
Publikováno v: JCI insight [JCI Insight] 2021 Feb 22; Vol. 6 (4). Date of Electronic Publication: 2021 Feb 22.
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