Protein Kinases - High Yield Targets for Cancer and Dementia Drug Discovery.

Autor: Shroff R; Department of Medicine, University of Arizona College of Medicine, Tucson., Goetzl EJ; Department of Medicine, University of California Medical Center, San Francisco. Electronic address: edward.goetzl@ucsf.edu.

Publikováno v: The American journal of medicine [Am J Med] 2024 Nov; Vol. 137 (11), pp. 1055-1058. Date of Electronic Publication: 2024 Jun 24.

Human Stem Cells in Regenerative Medicine.

Autor: Goetzl EJ; Department of Medicine, University of California Medical Center, San Francisco. Electronic address: edward.goetzl@ucsf.edu., Alpert JS; Department of Medicine, University of Arizona College of Medicine, Tucson; Editor-in-Chief, The American Journal of Medicine., Chen QM; College of Pharmacy, University of Arizona, Tucson.

Publikováno v: The American journal of medicine [Am J Med] 2024 Sep; Vol. 137 (9), pp. 805-809. Date of Electronic Publication: 2024 May 23.

Neuron-derived extracellular vesicles in blood reveal effects of exercise in Alzheimer's disease.

Autor: Delgado-Peraza F; Laboratory of Clinical Investigation, Intramural Research Program, National Institute On Aging, National Institutes of Health, Baltimore, MD, 21224, USA., Nogueras-Ortiz C; Laboratory of Clinical Investigation, Intramural Research Program, National Institute On Aging, National Institutes of Health, Baltimore, MD, 21224, USA., Simonsen AH; Danish Dementia Research Centre, Copenhagen University Hospital - Rigshospitalet, 2100, Copenhagen, Denmark., Knight DD; Laboratory of Clinical Investigation, Intramural Research Program, National Institute On Aging, National Institutes of Health, Baltimore, MD, 21224, USA., Yao PJ; Laboratory of Clinical Investigation, Intramural Research Program, National Institute On Aging, National Institutes of Health, Baltimore, MD, 21224, USA., Goetzl EJ; Department of Medicine, University of California San Francisco, San Francisco, CA, 94143, USA.; Research Department, Campus for Jewish Living, San Francisco, CA, 94112, USA., Jensen CS; Danish Dementia Research Centre, Copenhagen University Hospital - Rigshospitalet, 2100, Copenhagen, Denmark., Høgh P; Department of Neurology, Zealand University Hospital, 4000, Roskilde, Denmark.; Department of Clinical Medicine, University of Copenhagen, 1165, Copenhagen, Denmark., Gottrup H; Department of Neurology, Dementia Clinic, Aarhus University Hospital, 8200, Aarhus, Denmark., Vestergaard K; Department of Neurology, Dementia Clinic, Aalborg University Hospital, 9000, Aalborg, Denmark., Hasselbalch SG; Danish Dementia Research Centre, Copenhagen University Hospital - Rigshospitalet, 2100, Copenhagen, Denmark. steen.gregers.hasselbalch@regionh.dk., Kapogiannis D; Laboratory of Clinical Investigation, Intramural Research Program, National Institute On Aging, National Institutes of Health, Baltimore, MD, 21224, USA. kapogiannisd@mail.nih.gov.

Publikováno v: Alzheimer's research & therapy [Alzheimers Res Ther] 2023 Sep 20; Vol. 15 (1), pp. 156. Date of Electronic Publication: 2023 Sep 20.

Single-extracellular vesicle (EV) analyses validate the use of L1 Cell Adhesion Molecule (L1CAM) as a reliable biomarker of neuron-derived EVs.

Autor: Nogueras-Ortiz CJ; Laboratory of Clinical Investigation, Intramural Research Program, National Institute on Aging, National Institutes of Health (NIA/NIH), Baltimore, Maryland, USA., Eren E; Laboratory of Clinical Investigation, Intramural Research Program, National Institute on Aging, National Institutes of Health (NIA/NIH), Baltimore, Maryland, USA., Yao P; Laboratory of Clinical Investigation, Intramural Research Program, National Institute on Aging, National Institutes of Health (NIA/NIH), Baltimore, Maryland, USA., Calzada E; Laboratory of Clinical Investigation, Intramural Research Program, National Institute on Aging, National Institutes of Health (NIA/NIH), Baltimore, Maryland, USA., Dunn C; Flow Cytometry Unit, Intramural Research Program, National Institute on Aging, National Institutes of Health (NIA/NIH), Baltimore, Maryland, USA., Volpert O; NeuroDex Inc., Natick, Maryland, USA., Delgado-Peraza F; Laboratory of Clinical Investigation, Intramural Research Program, National Institute on Aging, National Institutes of Health (NIA/NIH), Baltimore, Maryland, USA., Mustapic M; Laboratory of Clinical Investigation, Intramural Research Program, National Institute on Aging, National Institutes of Health (NIA/NIH), Baltimore, Maryland, USA., Lyashkov A; Laboratory of Clinical Investigation, Intramural Research Program, National Institute on Aging, National Institutes of Health (NIA/NIH), Baltimore, Maryland, USA., Rubio FJ; Neuronal Ensembles in Addiction Section, Behavioral Neuroscience Research Branch, Intramural Research Program/National Institute on Drug Abuse/National Institutes of Health, Baltimore, Maryland, USA., Vreones M; Laboratory of Clinical Investigation, Intramural Research Program, National Institute on Aging, National Institutes of Health (NIA/NIH), Baltimore, Maryland, USA., Cheng L; La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria, Australia., You Y; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA., Hill AF; La Trobe Institute for Molecular Science, La Trobe University, Bundoora, Victoria, Australia.; Institute for Health and Sport, Victoria University, Melbourne, Victoria, Australia., Ikezu T; Department of Neuroscience, Mayo Clinic, Jacksonville, Florida, USA.; Department of Pharmacology and Experimental Therapeutics, Boston University School of Medicine, Boston, Massachusetts, USA., Eitan E; NeuroDex Inc., Natick, Maryland, USA., Goetzl EJ; Department of Medicine, University of California, San Francisco, California, USA.; San Francisco Campus for Jewish Living, San Francisco, California, USA., Kapogiannis D; Laboratory of Clinical Investigation, Intramural Research Program, National Institute on Aging, National Institutes of Health (NIA/NIH), Baltimore, Maryland, USA.; Department of Neurology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.

Publikováno v: Journal of extracellular vesicles [J Extracell Vesicles] 2024 Jun; Vol. 13 (6), pp. e12459.

CRISPR-Cas Gene Editing to the Genetic Rescue.

Autor: Goetzl EJ; Department of Medicine, University of California San Francisco. Electronic address: edward.goetzl@ucsf.edu., Alpert JS; Department of Medicine, The University of Arizona College of Medicine, Tucson; Editor in Chief, The American Journal of Medicine.

Publikováno v: The American journal of medicine [Am J Med] 2024 May; Vol. 137 (5), pp. 386-389. Date of Electronic Publication: 2024 Jan 27.