Neoantigen-targeted dendritic cell vaccination in lung cancer patients induces long-lived T cells exhibiting the full differentiation spectrum

Autor: Ingels, Joline, De Cock, Laurenz, Stevens, Dieter, Mayer, Rupert L., Théry, Fabien, Sanchez, Guillem Sanchez, Vermijlen, David, Weening, Karin, De Smet, Saskia, Lootens, Nele, Brusseel, Marieke, Verstraete, Tasja, Buyle, Jolien, Van Houtte, Eva, Devreker, Pam, Heyns, Kelly, De Munter, Stijn, Van Lint, Sandra, Goetgeluk, Glenn, Bonte, Sarah, Billiet, Lore, Pille, Melissa, Jansen, Hanne, Pascal, Eva, Deseins, Lucas, Vantomme, Lies, Verdonckt, Maarten, Roelandt, Ria, Eekhout, Thomas, Vandamme, Niels, Leclercq, Georges, Taghon, Tom, Kerre, Tessa, Vanommeslaeghe, Floris, Dhondt, Annemieke, Ferdinande, Liesbeth, Van Dorpe, Jo, Desender, Liesbeth, De Ryck, Frederic, Vermassen, Frank, Surmont, Veerle, Impens, Francis, Menten, Björn, Vermaelen, Karim, Vandekerckhove, Bart

Publikováno v: In Cell Reports Medicine 21 May 2024 5(5)

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Cas9 RNP transfection by vapor nanobubble photoporation for ex vivo cell engineering

Autor: Raes, Laurens, Pille, Melissa, Harizaj, Aranit, Goetgeluk, Glenn, van Hoeck, Jelter, Stremersch, Stephan, Fraire, Juan C, Brans, Toon, de Jong, Olivier G, Maas - Bakker, Roel, Mastrobattista, Enrico, Vader, Pieter, de Smedt, Stefaan C, Vandekerckhove, Bart, Raemdonck, Koen, Braeckmans, Kevin, Afd Pharmaceutics, Pharmaceutics

Publikováno v: MOLECULAR THERAPY-NUCLEIC ACIDS
Molecular Therapy-Nucleic Acids, 25, 696. Cell Press
Molecular Therapy: Nucleic Acids, Vol 25, Iss, Pp 696-707 (2021)

The CRISPR-Cas9 technology represents a powerful tool for genome engineering in eukaryotic cells, advancing both fundamental research and therapeutic strategies. Despite the enormous potential of the technology, efficient and direct intracellular del

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39b7f8e5430f30f764d9ff5200f4d081
https://doi.org/10.1016/j.omtn.2021.08.014

Hydrogel-Induced Cell Membrane Disruptions Enable Direct Cytosolic Delivery of Membrane-Impermeable Cargo

Autor: Van Hoeck, Jelter, Van de Vyver, Thijs, Harizaj, Aranit, Goetgeluk, Glenn, Merckx, Pieterjan, Liu, Jing, Wels, Mike, Sauvage, Félix, De Keersmaecker, Herlinde, Vanhove, Christian, Vader, Pieter, de Jong, Olivier G., Dewitte, Heleen, Vandekerckhove, Bart, Braeckmans, Kevin, de Smedt, S.C., Raemdonck, Koen

Intracellular delivery of membrane-impermeable cargo offers unique opportunities for biological research and the development of cell-based therapies. Despite the breadth of available intracellular delivery tools, existing protocols are often suboptim

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______101::3a367c673c9fc0a61440e3d8391c3781
https://dspace.library.uu.nl/handle/1874/412767