Whole-genome association analysis of treatment response in obsessive-compulsive disorder

Autor: Qin, H, Samuels, JF, Wang, Y, Zhu, Y, Grados, MA, Riddle, MA, Greenberg, BD, Knowles, JA, Fyer, AJ, McCracken, JT, Murphy, DL, Rasmussen, SA, Cullen, BA, Piacentini, J, Geller, D, Stewart, SE, Pauls, D, Bienvenu, OJ, Goes, FS, Maher, B, Pulver, AE, Valle, D, Lange, C, Mattheisen, M, McLaughlin, NC, Liang, K-Y, Nurmi, EL, Askland, KD, Nestadt, G, Shugart, YY

Publikováno v: Molecular psychiatry, vol 21, iss 2

Up to 30% of patients with obsessive-compulsive disorder (OCD) exhibit an inadequate response to serotonin reuptake inhibitors (SRIs). To date, genetic predictors of OCD treatment response have not been systematically investigated using genome-wide a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b297a9ac6d195b9bac1eec4065469f0f
https://escholarship.org/uc/item/96f3141t

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Whole-exome sequencing of 81 individuals from 27 multiply affected bipolar disorder families

Autor: Fermín Mayoral, Fabio Rivas, Jesus Haro González, Franziska Degenhardt, Julian Hecker, Fermin Perez Perez, Marcella Rietschel, Michael Bauer, Margot Albus, Markus M. Nöthen, Sascha B. Fischer, Susana Gil Flores, Francisco del Río Noriega, Mehdi Pirooznia, Stefan Herms, Jana Strohmaier, Stephanie H. Witt, Fernando S. Goes, Margitta Borrmann-Hassenbach, Anna Maaser-Hecker, Sugirthan Sivalingam, Sven Cichon, Lorena M. Schenk, Georg Auburger, Andreas Reif, Fabian Streit, María González, Francisco J. Cabaleiro Fabeiro, Peter Nürnberg, Jose Guzman-Parra, Andreas J. Forstner, Holger Thiele, Guillermo Orozco Diaz, Andrea Pfennig, Céline S. Reinbold, Johannes Schumacher, Per Hoffmann

Publikováno v: Translational Psychiatry, Vol 10, Iss 1, Pp 1-10 (2020)
Translational Psychiatry 10, 59 (2020). doi:10.1038/s41398-020-0732-y
Translational Psychiatry 10(1), 57 (2020). doi:10.1038/s41398-020-0732-y
Translational Psychiatry

Bipolar disorder (BD) is a highly heritable neuropsychiatric disease characterized by recurrent episodes of depression and mania. Research suggests that the cumulative impact of common alleles explains 25–38% of phenotypic variance, and that rare v

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83391e776df9b8fe476990e7a4d4bcf9
https://hdl.handle.net/10668/15117

Exploring the genetics of lithium response in bipolar disorders.

Autor: Herrera-Rivero M; Department of Psychiatry, University of Münster and Joint Institute for Individualisation in a Changing Environment (JICE), University of Münster and Bielefeld University, Albert-Schweitzer-Campus 1, Building A9, 48149, Münster, Germany., Adli M; Department of Psychiatry and Psychotherapy, Charité, Universitätsmedizin Berlin, Campus Charité Mitte, Berlin, Germany.; Fliedner Klinik Berlin, Berlin, Germany., Akiyama K; Department of Biological Psychiatry and Neuroscience, Dokkyo Medical University School of Medicine, Mibu, Japan., Akula N; Intramural Research Program, National Institute of Mental Health, National Institutes of Health, US Department of Health & Human Services, Baltimore, USA., Amare AT; Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, SA, Australia., Ardau R; Unit of Clinical Pharmacology, Hospital University Agency of Cagliari, Cagliari, Italy., Arias B; Unitat de Zoologia i Antropologia Biològica (Dpt. Biologia Evolutiva, Ecologia i Ciències Ambientals), Facultat de Biologia and Institut de Biomedicina (IBUB), University of Barcelona, CIBERSAM, Barcelona, Spain., Aubry JM; Department of Psychiatry, Division of Psychiatric Specialities, Geneva University Hospitals, Geneva, Switzerland.; Faculty of Medicine, University of Geneva, Geneva, Switzerland., Backlund L; Department of Molecular Medicine and Surgery and Center for Molecular Medicine at Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden., Bellivier F; Département de Psychiatrie et de Médecine Addictologique, INSERM UMR-S 1144, Université Paris Cité, AP-HP, Groupe Hospitalier Saint-Louis-Lariboisière, F. Widal, Paris, France., Benabarre A; Bipolar Disorder Program, Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, Barcelona, Spain., Bengesser S; Department of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Graz, Austria., Bhattacharjee AK; Department of Psychiatry, University of California San Diego, San Diego, USA., Biernacka JM; Department of Health Sciences Research, Mayo Clinic, Rochester, USA.; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, USA., Birner A; Department of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Graz, Austria., Cearns M; Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, SA, Australia., Cervantes P; The Neuromodulation Unit, McGill University Health Centre, Montreal, Canada., Chen HC; Department of Psychiatry & Center of Sleep Disorders, National Taiwan University Hospital, Taipei, Taiwan., Chillotti C; Unit of Clinical Pharmacology, Hospital University Agency of Cagliari, Cagliari, Italy., Cichon S; Human Genomics Research Group, Department of Biomedicine, University Hospital Basel, Basel, Switzerland.; Institute of Medical Genetics and Pathology, University Hospital Basel, Basel, Switzerland.; Institute of Neuroscience and Medicine (INM-1), Research Center Jülich, Jülich, Germany., Clark SR; Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, SA, Australia., Colom F; Mental Health Research Group, IMIM-Hospital del Mar, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain., Cruceanu C; Douglas Mental Health University Institute, McGill University, Montreal, Canada., Czerski PM; Psychiatric Genetic Unit, Poznan University of Medical Sciences, Poznań, Poland., Dalkner N; Department of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Graz, Austria., Degenhardt F; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Del Zompo M; Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., DePaulo JR; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, USA., Etain B; Département de Psychiatrie et de Médecine Addictologique, INSERM UMR-S 1144, Université Paris Cité, AP-HP, Groupe Hospitalier Saint-Louis-Lariboisière, F. Widal, Paris, France., Falkai P; Department of Psychiatry and Psychotherapy, Ludwig-Maximilian-University Munich, Munich, Germany., Ferensztajn-Rochowiak E; Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznań, Poland., Forstner AJ; Institute of Neuroscience and Medicine (INM-1), Research Center Jülich, Jülich, Germany.; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Frank J; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Frisén L; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden., Frye MA; Department of Psychiatry and Psychology, Mayo Clinic, Rochester, USA., Fullerton JM; Neuroscience Research, Australia and School of Biomedical Sciences, University of New South Wales, Sydney, Australia., Gallo C; Laboratorios de Investigación y Desarrollo, Facultad de Ciencias y Filosofía, Universidad Peruana Cayetano Heredia, San Martín de Porres, Peru., Gard S; Service de Psychiatrie, Hôpital Charles Perrens, Bordeaux, France., Garnham JS; Department of Psychiatry, Dalhousie University, Halifax, Canada., Goes FS; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, USA., Grigoroiu-Serbanescu M; Biometric Psychiatric Genetics Research Unit, Alexandru Obregia Clinical Psychiatric Hospital, Bucharest, Romania., Grof P; Mood Disorders Center of Ottawa, Ottawa, Canada., Hashimoto R; Department of Pathology of Mental Diseases, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan., Hasler R; Department of Psychiatry, Division of Psychiatric Specialities, Geneva University Hospitals, Geneva, Switzerland., Hauser J; Psychiatric Genetic Unit, Poznan University of Medical Sciences, Poznań, Poland., Heilbronner U; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany., Herms S; Human Genomics Research Group, Department of Biomedicine, University Hospital Basel, Basel, Switzerland.; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Hoffmann P; Human Genomics Research Group, Department of Biomedicine, University Hospital Basel, Basel, Switzerland.; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., Hou L; Intramural Research Program, National Institute of Mental Health, National Institutes of Health, US Department of Health & Human Services, Baltimore, USA., Hsu YH; Program for Quantitative Genomics, Harvard School of Public Health and HSL Institute for Aging Research, Harvard Medical School, Boston, USA., Jamain S; Univ. Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, Fondation FondaMental, Créteil, France., Jiménez E; Bipolar and Depressive Disorders Unit, Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, ISCIII, Barcelona, Spain., Kahn JP; Service de Psychiatrie et Psychologie Clinique, Centre Psychothérapique de Nancy - Université, Nancy, France., Kassem L; Intramural Research Program, National Institute of Mental Health, National Institutes of Health, US Department of Health & Human Services, Baltimore, USA., Kato T; Department of Psychiatry & Behavioral Science, Graduate School of Medicine, Juntendo University, Tokyo, Japan., Kelsoe J; Department of Psychiatry, University of California San Diego, San Diego, USA., Kittel-Schneider S; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Würzburg, Würzburg, Germany., Kuo PH; Department of Public Health & Institute of Epidemiology and Preventive Medicine, College of Public Health, National Taiwan University, Taipei, Taiwan., Kusumi I; Department of Psychiatry, Hokkaido University Graduate School of Medicine, Sapporo, Japan., König B; Department of Psychiatry and Psychotherapeutic Medicine, Landesklinikum Neunkirchen, Neunkirchen, Austria., Laje G; Intramural Research Program, National Institute of Mental Health, National Institutes of Health, US Department of Health & Human Services, Baltimore, USA., Landén M; Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the Gothenburg University, Gothenburg, Sweden.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Lavebratt C; Department of Molecular Medicine and Surgery and Center for Molecular Medicine at Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden., Leboyer M; Univ. Paris Est Créteil, INSERM, IMRB, Translational Neuropsychiatry, AP-HP, Mondor University Hospital, DMU Impact, Fondation FondaMental, Créteil, France., Leckband SG; Office of Mental Health, VA San Diego Healthcare System, California, USA., Maj M; Department of Psychiatry, University of Campania 'Luigi Vanvitelli', Caserta, Italy., Manchia M; Section of Psychiatry, Department of Medical Sciences and Public Health, University of Cagliari, Cagliari, Italy.; Department of Pharmacology, Dalhousie University, Halifax, Canada., Marie-Claire C; Université Paris Cité, Inserm UMR-S 1144, Optimisation Thérapeutique en Neuropsychopharmacologie, 75006, Paris, France., Martinsson L; Department of Clinical Neurosciences, Karolinska Institutet, Stockholm, Sweden., McCarthy MJ; Department of Psychiatry, University of California San Diego, San Diego, USA.; Department of Psychiatry, VA San Diego Healthcare System, San Diego, CA, USA., McElroy SL; Department of Psychiatry, Lindner Center of Hope/University of Cincinnati, Cincinnati, USA., Millischer V; Department of Molecular Medicine and Surgery and Center for Molecular Medicine at Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden.; Department of Psychiatry and Psychotherapy, Comprehensive Center for Clinical Neurosciences and Mental Health, Medical University of Vienna, Vienna, Austria., Mitjans M; Centro de Investigación Biomédica en Red de Salud Mental (CIBERSAM), Instituto de Salud Carlos III, Madrid, Spain.; Department of Genetics, Microbiology and Statistics, Faculty of Biology, Institut de Biomedicina de La Universitat de Barcelona (IBUB), University of Barcelona, Barcelona, Spain., Mondimore FM; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, USA., Monteleone P; Department of Medicine, Surgery and Dentistry 'Scuola Medica Salernitana', University of Salerno, Baronissi, Italy., Nievergelt CM; Department of Psychiatry, University of California San Diego, San Diego, USA., Novák T; National Institute of Mental Health, Klecany, Czech Republic., Nöthen MM; Institute of Human Genetics, University of Bonn, School of Medicine & University Hospital Bonn, Bonn, Germany., O'Donovan C; Department of Psychiatry, Dalhousie University, Halifax, Canada., Ozaki N; Department of Psychiatry & Department of Child and Adolescent Psychiatry, Nagoya University Graduate School of Medicine, Nagoya, Japan., Papiol S; Department of Psychiatry and Psychotherapy, Ludwig-Maximilian-University Munich, Munich, Germany.; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany., Pfennig A; Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, Dresden, Germany., Pisanu C; Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Potash JB; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, USA., Reif A; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt, Germany., Reininghaus E; Department of Psychiatry and Psychotherapeutic Medicine, Research Unit for Bipolar Affective Disorder, Medical University of Graz, Graz, Austria., Richard-Lepouriel H; Department of Psychiatry, Division of Psychiatric Specialities, Geneva University Hospitals, Geneva, Switzerland.; Faculty of Medicine, University of Geneva, Geneva, Switzerland., Roberts G; School of Psychiatry, University of New South Wales, Sydney, Australia., Rouleau GA; Montreal Neurological Institute and Hospital, McGill University, Montreal, Canada., Rybakowski JK; Department of Adult Psychiatry, Poznan University of Medical Sciences, Poznań, Poland., Schalling M; Department of Molecular Medicine and Surgery and Center for Molecular Medicine at Karolinska University Hospital, Karolinska Institute, Stockholm, Sweden., Schofield PR; Neuroscience Research, Australia and School of Biomedical Sciences, University of New South Wales, Sydney, Australia., Schubert KO; Discipline of Psychiatry, School of Medicine, University of Adelaide, Adelaide, SA, Australia.; Northern Adelaide Local Health Network, Mental Health Services, Adelaide, Australia., Schulte EC; Department of Psychiatry and Psychotherapy, Ludwig-Maximilian-University Munich, Munich, Germany.; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Psychotherapy, University Hospital Bonn, Medical Faculty University of Bonn, Bonn, Germany., Schweizer BW; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, USA., Severino G; Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Shekhtman T; Department of Psychiatry, University of California San Diego, San Diego, USA., Shilling PD; Department of Psychiatry, University of California San Diego, San Diego, USA., Shimoda K; Department of Psychiatry, Dokkyo Medical University School of Medicine, Mibu, Japan., Simhandl C; Medical Faculty, Bipolar Center Wiener Neustadt, Sigmund Freud University, Vienna, Austria., Slaney CM; Department of Psychiatry, Dalhousie University, Halifax, Canada., Squassina A; Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Stamm T; Department of Psychiatry and Psychotherapy, Charité, Universitätsmedizin Berlin, Campus Charité Mitte, Berlin, Germany., Stopkova P; National Institute of Mental Health, Klecany, Czech Republic., Streit F; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Tekola-Ayele F; Epidemiology Branch, Division of Intramural Population Health Research, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, USA., Thalamuthu A; Centre for Healthy Brain Ageing (CHeBA), School of Psychiatry, University of New South Wales, Sydney, Australia., Tortorella A; Department of Psychiatry, University of Perugia, Perugia, Italy., Turecki G; Douglas Mental Health University Institute, McGill University, Montreal, Canada., Veeh J; Department of Psychiatry, Psychosomatic Medicine and Psychotherapy, University Hospital Frankfurt, Frankfurt, Germany., Vieta E; Bipolar and Depressive Disorders Unit, Institute of Neuroscience, Hospital Clinic, University of Barcelona, IDIBAPS, CIBERSAM, ISCIII, Barcelona, Spain., Viswanath B; Department of Psychiatry, National Institute of Mental Health and Neurosciences, Bangalore, 560029, India., Witt SH; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Zandi PP; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA., Alda M; Department of Psychiatry, Dalhousie University, Halifax, Canada., Bauer M; Department of Psychiatry and Psychotherapy, University Hospital Carl Gustav Carus, Medical Faculty, Technische Universität Dresden, Dresden, Germany., McMahon FJ; Intramural Research Program, National Institute of Mental Health, National Institutes of Health, US Department of Health & Human Services, Baltimore, USA., Mitchell PB; School of Psychiatry, University of New South Wales, Sydney, Australia., Rietschel M; Department of Genetic Epidemiology in Psychiatry, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Heidelberg, Germany., Schulze TG; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, USA.; Institute of Psychiatric Phenomics and Genomics (IPPG), University Hospital, LMU Munich, Munich, Germany.; Department of Psychiatry and Behavioral Sciences, Norton College of Medicine, SUNY Upstate Medical University, Syracuse, NY, USA., Baune BT; Department of Psychiatry, University of Münster and Joint Institute for Individualisation in a Changing Environment (JICE), University of Münster and Bielefeld University, Albert-Schweitzer-Campus 1, Building A9, 48149, Münster, Germany. Bernhard.Baune@ukmuenster.de.; Department of Psychiatry, Melbourne Medical School, University of Melbourne and The Florey Institute of Neuroscience and Mental Health, The University of Melbourne, Melbourne, Australia. Bernhard.Baune@ukmuenster.de.

Publikováno v: International journal of bipolar disorders [Int J Bipolar Disord] 2024 Jun 12; Vol. 12 (1), pp. 20. Date of Electronic Publication: 2024 Jun 12.

Genome-wide association study identifies 30 obsessive-compulsive disorder associated loci.

Autor: Strom NI; Department of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany.; Department of Psychiatric Phenomics and Genomics (IPPG), Ludwig-Maximilians University Munich, Munich, Germany.; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Services, Region Stockholm , Stockholm, Sweden.; Department of Biomedicine, Aarhus University, Aarhus, Denmark., Gerring ZF; Department of Mental Health and Neuroscience, Translational Neurogenomics, QIMR Berghofer Medical Research Institute, Brisbane, QLD, Australia.; Department of Population Health and Immunity, Healthy Development and Ageing, Walter and Eliza Hall Institute of Medical Research, Melbourne, Victoria, Australia., Galimberti M; Department of Psychiatry, Human Genetics, Yale University, New Haven, CT, USA.; VA Connecticut Healthcare System, West Haven, CT, USA., Yu D; Department of Center for Genomic Medicine, Psychiatric and Neurodevelopmental Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute, Cambridge, MA, USA., Halvorsen MW; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Abdellaoui A; Department of Psychiatry, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands., Rodriguez-Fontenla C; CIMUS (Center for Research in Molecular Medicine and Chronic Diseases), Genomics and Bioinformatics, University of Santiago de Compostela, Santiago de Compostela, A Coruña, Spain.; Grupo de Medicina Xenómica, Genetics, FIDIS (Instituto de Investigación Sanitaria de Santiago de Compostela), Santiago de Compostela, A Coruña, Spain., Sealock JM; Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Bigdeli T; Department of Psychiatry and Behavioral Sciences, SUNY Downstate Health Sciences University, Brooklyn, NY, USA.; VA NY Harbor Healthcare System, Brooklyn, NY, USA., Coleman JR; Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom.; National Institute for Health and Care Research Maudsley Biomedical Research Centre, South London and Maudsley NHS Trust, London, United Kingdom., Mahjani B; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Thorp JG; Mental Health and Neuroscience Program, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Faculty of Medicine, School of Biomedical Sciences, University of Queensland, Brisbane, Queensland, Australia., Bey K; Department of Psychiatry and Psychotherapy, University Hospital Bonn, Bonn, Germany., Burton CL; Department of Neurosciences and Mental Health, Hospital for Sick Children, Toronto, ON, Canada., Luykx JJ; Department of Psychiatry, Brain, University Medical Center Utrecht, Utrecht, The Netherlands.; Second opinion outpatient clinic, GGNet, Warnsveld, The Netherlands., Zai G; Molecular Brain Science Department, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health,, Toronto, ON, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON, Canada., Alemany S; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.; Department of Mental Health, Hospital Universitari Vall d'Hebron, Barcelona, Spain.; Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain., Andre C; Obsessive-Compulsive Disorder Institute, McLean Hospital, Belmont, MA, USA., Askland KD; Department of Psychiatry & Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada., Banaj N; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy., Barlassina C; Department of Heath Sciences, University of Milano, Milano, Italy., Nissen JB; Department of Child and Adolescent Psychiatry, Aarhus University Hospital, Psychiatry, Aarhus, Denmark.; Institute of Clinical Medicine, Health, Aarhus University, Aarhus, Denmark., Bienvenu OJ; Department of Psychiatry and Behavioral Sciences, General Hospital Psychiatry, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Black D; Departments of Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USA., Bloch MH; Department of Child Study Center and Psychiatry, Yale University, New Haven, CT, USA., Boberg J; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Services, Region Stockholm , Stockholm, Sweden., Børte S; Department of Research and Innovation, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.; Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, HUNT Center for Molecular and Clinical Epidemiology, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway., Bosch R; Department of Child and Adolescent Mental Health, Hospital Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain.; Instituto de Salut Carlos III, Centro de Investigación Biomédica en Red de Salut Mental (CIBERSAM), Madrid, Spain., Breen M; Department of Psychiatry, Icahn School of Medicine At Mount Sinai, New York, NY, USA.; Seaver Autism Center for Research and Treatment, Icahn School of Medicine At Mount Sinai, New York, NY, USA.; The Mindich Child Health and Development Institute, Icahn School of Medicine At Mount Sinai, New York, NY, USA., Brennan BP; Obsessive-Compulsive Disorder Institute, McLean Hospital, Belmont, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Brentani H; Department of Psychiatry, Universidade De São Paulo, São Paulo, Brazil., Buxbaum JD; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bybjerg-Grauholm J; Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark., Byrne EM; Child Health Research Centre, University of Queensland, Brisbane, Queensland, Australia., Cabana-Dominguez J; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.; Department of Mental Health, Hospital Universitari Vall d'Hebron, Barcelona, Spain.; Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain., Camarena B; Pharmacogenetics Department, Investigaciones Clínicas, Instituto Nacional de Psiquiatría Ramon de la Fuente Muñiz, Mexico City, México., Camarena A; Department of Surgery, Duke, Durham, NC, USA., Cappi C; Department of Psychiatry, Icahn School of Medicine at Mount Sinai Hospital, New York, NY, USA.; Department of Psychiatry, University of Sao Paulo, Sao Paulo, Brazil., Carracedo A; Center for Research in Molecular Medicine and Chronic Diseases (CiMUS), Genomics and Bioinformatics Group, University of Santiago de Compostela, Santiago de Compostela, Spain.; Galiician Foundation of Genomic Medicine, Grupo de Medicina Xenómica, Instituto de Investigación Sanitaria de Santiago -IDIS-, Santiago de Compostela, Spain.; Medicina Genómica, Centro de Investigación Biomédica en Red, Enfermedades Raras (CIBERER), Santiago de Compostela, Spain., Casas M; Programa MIND Escoles, Hospital Sant Joan de Déu , Esplugues de Llobregat, Barcelona, Spain.; Departamento de Psiquiatría y Medicina Legal, Universitat Autònoma de Barcelona, Bellaterra, Spain., Cavallini MC; Department of Psychiatry, Ospedale San Raffaele, Milano, Italy., Ciullo V; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy., Cook EH; Department of Psychiatry, University of Illinois Chicago, Chicago, IL, USA., Crosby J; Obsessive-Compulsive Disorder Institute, McLean Hospital, Belmont, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Cullen BA; Department of Psychiatry and Behavioral Sciences, Johns Hopkins Medical Institutions, Baltimore , MD, USA.; Department of Mental Health, Bloomberg School of Public Health, Baltimore, MD, USA., De Schipper EJ; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Services, Region Stockholm , Stockholm, Sweden., Delorme R; Child and Adolesccent Psycchiatry Department, APHP, Paris, France., Djurovic S; Department of Medical Genetics, Oslo University Hospital, Oslo, Norway.; Department of Clinical Science, University of Bergen, Bergen, Norway., Elias JA; Psychiatry, McLean Hospital OCDI, Harvard Medical School, Belmont, MA, USA.; Adult Psychological Services, CBTeam LLC, Lexington, MA, USA., Estivill X; qGenomics (Quantitative Genomics Laboratories), Esplugues de Llobregat, Barcelona, Spain., Falkenstein MJ; Obsessive-Compulsive Disorder Institute, McLean Hospital, Belmont, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Fundin BT; Department of Medical Epidemiology and Biostatistics, Center for Eating Disorders Innovation, Karolinska Institutet, Stockholm, Sweden., Garner L; Obsessive-Compulsive Disorder Institute, McLean Hospital, Belmont, MA, USA., German C; 23andMe, Inc., Sunnyvale, CA, USA., Gironda C; Obsessive-Compulsive Disorder Institute, McLean Hospital, Belmont, MA, USA., Goes FS; Department of Psychiatry, Johns Hopkins University, Baltimore, MD, USA., Grados MA; Department of Psychiatry and Behavioral Sciences, Child & Adolescent Psychiatry, Johns Hopkins University, Baltimore, MD, USA., Grove J; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; Center for Genomics and Personalized Medicine, Aarhus, Denmark.; Bioinformatics Research Centre, Aarhus, Denmark., Guo W; Genetic Epidemiology Research Branch, National Institute of Mental Health, Bethesda, MD, USA., Haavik J; Department of Biomedicine, University of Bergen, Bergen, Norway.; Bergen Center for Brain Plasticity, Division of Psychiatry, Haukeland University Hospital, Bergen, Norway., Hagen K; Department of Psychiatry, Møre og Romsdal Hospital Trust, Molde, Norway.; Bergen Center for Brain Plasticity, Psychiatry, Haukeland University Hospital, Bergen, Norway.; Department of Mental Health, Norwegian University for Science and Technology, Trondheim, Norway., Harrington K; Million Veteran Program (MVP) Coordinating Center, VA Boston Healthcare System, Boston, MA, USA.; Department of Psychiatry, Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA., Havdahl A; PsychGen Centre for Genetic Epidemiology and Mental Health, Norwegian Institute of Public Health, Oslo, Norway.; Nic Waals Institute, Lovisenberg Diaconal Hospital, Oslo, Norway., Höffler KD; Department of Clinical Science, University of Bergen, Bergen, Norway.; Bergen Center for Brain Plasticity, Haukeland University Hospital, Bergen, Norway.; Department of Medical Genetics, Dr. Einar Martens Research Group for Biological Psychiatry, Haukeland University Hospital, Bergen, Norway., Hounie AG; Department of Psychiatry, University of São Paulo, São Paulo, Brazil., Hucks D; Department of Medicine, Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Hultman C; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Janecka M; Department of Child and Adolescent Psychiatry, NYU Grossman School of Medicine, New York, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, USA., Jenike E; Obsessive-Compulsive Disorder Institute, McLean Hospital, Belmont, MA, USA., Karlsson EK; Department of Bioinformatics and Integrative Biology, University of Massachusetts Medical School, Worcester, MA, USA.; Department of Vertebrate Genomics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kelley K; Obsessive-Compulsive Disorder Institute, McLean Hospital, Belmont, MA, USA., Klawohn J; Department of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany.; Department of Medicine, MSB Medical School Berlin, Berlin, Germany., Krasnow JE; Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MD, USA., Krebs K; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Lange C; Department of Biostatistics, T.H. Chan School of Public Health, Boston, MA, USA.; Department of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA, USA., Lanzagorta N; Research Department, Grupo Medico Carracci, Mexico City, Mexico., Levey D; Department of Psychiatry, Yale University, West Haven, CT, USA.; Office of Research & Development, United States Department of Veterans Affairs, West Haven, CT, USA., Lindblad-Toh K; Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden.; Department of Vertebrate Genomics, Broad Institute, Cambridge, MA, USA., Macciardi F; Department of Psychiatry, University of California, Irvine (UCI), Irvine, CA, USA., Maher B; Department of Mental Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Mathes B; Obsessive-Compulsive Disorder Institute, McLean Hospital, Belmont, MA, USA., McArthur E; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, TN, USA., McGregor N; COBRE Center for Neuromodulation, Butler Hospital, Providence, RI, USA., McLaughlin NC; Department of Psychiatry & Human Behavior, Alpert Medical School, Brown University, Providence, RI, USA.; Butler Hospital, Providence, RI, USA., Meier S; Department of Psychiatry, Dalhousie University, Halifax, NS, Canada., Miguel EC; Department of Psychiatry, Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil., Mulhern M; Department of Psychiatry and Psychotherapy, University Hospital Bonn, Bonn, Germany., Nestadt PS; Department of Psychiatry and Behavioral Science, Johns Hopkins University, Baltimore, MD, USA., Nurmi EL; Department of Psychiatry and Biobehavioral Sciences, Division of Child and Adolescent Psychiatry, University of California, Los Angeles, Los Angeles, CA, USA., O'Connell KS; Department of Clinical Medicine, Division of Mental Health and Addiction, Oslo University Hospital, Oslo, Norway.; NORMENT, University of Oslo, Oslo, Norway., Osiecki L; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Psychiatric and Neurodevelopmental Genetics Unit, Harvard Medical School, Boston, MA, USA., Ousdal OT; Department of Biomedicine, University of Bergen, Bergen, Norway.; Department of Biomedicine, Haukeland University Hospital, Bergen, Norway., Palviainen T; Institute for Molecular Medicine Finland - FIMM, University of Helsinki, Helsinki, Finland., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Piras F; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy., Piras F; Department of Clinical Neuroscience and Neurorehabilitation, Neuropsychiatry Laboratory, IRCCS Santa Lucia Foundation, Rome, Italy., Potluri S; Obsessive-Compulsive Disorder Institute, McLean Hospital, Belmont, MA, USA., Rabionet R; Department of Genetics, microbiology and statistics, IBUB, Universitat de Barcelona, Barcelona, Spain.; CIBERER, Centro de investigación biomédica en red, Madrid, Spain.; Department of Human Molecular Genetics, Institut de Recerca Sant Joan de Déu, Esplugues de Llobregat, Barcelona, Spain., Ramirez A; Department of Psychiatry and Psychotherapy, Division of Neurogenetics and Molecular Psychiatry, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Medical Faculty, Bonn, Germany.; DZNE Bonn, German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Psychiatry and Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, UT Health San Antonio, San Antonio, TX, USA.; Cologne Excellence Cluster for Stress Responses in Ageing-associated diseases (CECAD), University of Cologne, Cologne, Germany., Rauch S; Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, MA, USA., Reichenberg A; Department of Mental disorders, Norwegian Institute of Public Health, New York, NY, USA., Riddle MA; Department of Psychiatry and Behavioral Sciences, Child and Adolescent, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Ripke S; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin, Berlin, Germany.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA.; site Berlin-Potsdam, German Center for Mental Health (DZPG), Berlin, Germany., Rosário MC; Department of Psychiatry, Child and Adolescent Psychiatry Unit (UPIA), Federal University of São Paulo (UNIFESP), São Paulo, Brazil., Sampaio AS; Department of Neurosciences and Mental Health, Medical School, Federal University of Bahia, Salvador, Brazil., Schiele MA; Department of Psychiatry and Psychotherapy, Faculty of Medicine, University of Freiburg, Medical Center - University of Freiburg, Freiburg, Germany., Skogholt AH; Department of Public Health and Nursing, HUNT Center for Molecular and Clinical Epidemiology, Trondheim, Norway., Sloofman LGSG; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Smit J; Department of Psychiatry, Faculty of Medicine, Locaion Vumc, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Soler AM; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.; Department of Mental Health, Hospital Universitari Vall d'Hebron, Barcelona, Spain.; Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain.; Department of Genetics, Microbiology, and Statistics, Faculty of Biology, Universitat de Barcelona (UB), Barcelona, Spain., Thomas LF; Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Public Health and Nursing, K. 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Jebsen Center for Genetic Epidemiology, Norwegian University of Science and Technology, Trondheim, Norway.; BioCore - Bioinformatics Core Facility, Norwegian University of Science and Technology, Trondheim, Norway.; Clinic of Laboratory Medicine, St.Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Tifft E; Obsessive-Compulsive Disorder Institute, McLean Hospital, Belmont, MA, USA., Vallada H; Department of Psychiatry, Universidade de Sao Paulo, São Paulo, Brazil.; Department of Molecular Medicine and Surgery, CMM, Karolinska Institutet, Stockholm, Sweden., van Kirk N; OCD Institute, Division of Depression and Anxiety, McLean Hospital, Belmont, MA, USA.; Department of Psychiatry, Harvard Medical School, Belmont, MA, USA., Veenstra-VanderWeele J; Department of Psychiatry, Division of Child and Adolescent Psychiatry, Columbia University, New York, NY, USA.; Department of Child and Adolescent Psychiatry, New York State Psychiatric Institute, New York, NY, USA., Vulink NN; Department of Psychiatry, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Walker CP; Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ, USA., Wang Y; Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA., Wendland JR; Laboratory of Clinical Science, NIMH Intramural Research Program, Bethesda, MD, USA., Winsvold BS; Department of Research and Innovation, Division of Clinical Neuroscience, Oslo University Hospital, Oslo, Norway.; Department of Neurology, Oslo University Hospital, Oslo, Norway.; HUNT Center for Molecular and Clinical Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway., Yao Y; Department of Computional Biology, Institute of Life Science, Fudan University, Fudan, China., Zhou H; Department of Psychiatry, Yale School of Medicine, New Haven, CT, USA.; Department of Psychiatry, Veterans Affairs Connecticut Healthcare System, West Haven, CT, USA.; Section of Biomedical Informatics and Data Science, Yale School of Medicine, New Haven, CT, USA., Agrawal A; Department of Psychiatry, Washington University School of Medicine, Saint Louis, MO, USA., Alonso P; Department of Psychiatry, OCD Clinical and Research Unit, Bellvitge Hospital, Barcelona, Spain.; Department of Clinical Sciences, University of Barcelona, Barcelona, Spain.; Department of Psychiatry and Mental Health, Bellvitge Biomedical Research Institute IDIBELLL, Barcelona, Spain.; CIBERSAM, Mental Health Network Biomedical Research Center, Madrid, Spain., Berberich G; Psychosomatic Department, Windach Hospital of Neurobehavioural Research and Therapy, Windach, Germany., Bucholz KK; Department of Psychiatry, Washington U. School of Medicine, St Louis, MO, USA., Bulik CM; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Nutrition, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA., Cath D; Departments of Rijksuniversiteit Groningen and Psychiatry, University Medical Center Groninge, Groningen, The Netherlands.; Department of Specialized Training, Drenthe Mental Health Care Institute, Groningen, The Netherlands., Denys D; Department of Psychiatry, Institute of The Royal Netherlands Academy of Arts and Sciences (NIN-KNAW), Amsterdam, The Netherlands., Eapen V; Discipline of Psychiatry and Mental Health, School of Clinical Medicine, UNSW, Sydney, NSW, Australia.; Academic Unit of Child Psychiatry South-West Sydney (AUCS), South-West Sydney Clinical School, SWSLHD & Ingham Institute, Sydney, NSW, Australia., Edenberg H; Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, IN, USA., Falkai P; Department of Psychiatry and Psychotherapy, University Hospital LMU, Munich, Germany.; Department of Psychiatry, Max Planck Institute, Munich, Germany., Fernandez TV; Child Study Center and Psychiatry, Yale School of Medicine, New Haven, CT, USA., Fyer AJ; Department of Psychiatry, New York State Psychiatric Institute, New York, NY, USA.; Department of Psychiatry, , Columbia University Medical Center, New York, NY, USA., Gaziano JM; Department of Medicine, VA Boston Healthcare System, Boston, MA, USA.; Department of Medicine, Mass General Brigham, Boston, MA, USA., Geller DA; Department of Psychiatry, Child Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Grabe HJ; Department of Psychiatry & Psychotherapy, University Medicine Greifswald, Greifswald, Germany., Greenberg BD; COBRE Center on Neuromodulation, Butler Hospital, Providence, RI, USA.; Center for Neurorestoration and Neurotechnology, VA Providence Healthcare System, Providence, USA.; Department of Psychiatry and Human Behavior, Alpert Medical School, Brown University, Providence, RI, USA., Hanna GL; Department of Psychiatry, Child and Adolescent Psychiatry, University of Michigan, Ann Arbor, MI, USA., Hickie IB; Brain and Mind Centre, The University of Sydney, Sydney, NSW, Australia., Hougaard DM; Department for Congenital Disorders, Statens Serum Institut, Copenhagen, Denmark.; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark., Kathmann N; Department of Psychology, Humboldt-Universität zu Berlin, Berlin, Germany., Kennedy J; Department of Psychiatry, University of Toronto, Toronto, ON, Canada., Lai D; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA., Landén M; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, University of Gothenburg, Gothenburg, Sweden., Le Hellard S; Bergen Center for brain plasticity, Division of Psychiatry, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Science, University of Bergen, Bergen, Norway., Leboyer M; Department of Addictology and Psychiatry, Univ Paris Est Créteil, AP-HP, Inserm, Paris, France., Lochner C; Department of Psychiatry, SA MRC Unit on Risk and Resilience in Mental Disorders, Stellenbosch University, Stellenbosch, South Africa., McCracken JT; Department of Psychiatry and Biobehavioral Sciences, Division of Child and Adolescent Psychiatry, University of California, Los Angeles, Los Angeles, CA, USA., Medland SE; Department of Mental Health, Psychiatric Genetics, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Mortensen PB; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, Denmark.; National Centre for Register-based Research, Aarhus University, Aarhus, Denmark.; Centre for Integrated Register-based Research, Aarhus University, Aarhus, Denmark., Neale BM; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, , Broad Institute of Harvard and MIT, Cambridge, MA, USA., Nicolini H; Department of Psychiatry, Psychiatry, Carracci Medical Group, Mexico City, México.; Psiquiatría, Instituto Nacional de Medicina Genómica, Mexico City, México., Nordentoft M; Mental Health Center Copenhagen, Copenhagen Research Center for Mental Health, Mental Health services in the Capital Region of Denmark, Copenhagen, Denmark.; Faculty of Health and Medical Sciences, Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Pato M; Department of Psychiatry, Rutgers University, Piscataway, NJ, USA., Pato C; Department of Psychiatry, Rutgers University, Piscataway, NJ, USA., Pauls DL; Department of Psychiatry, Harvard Medical School, Boston, MA, USA., Piacentini J; Department of Psychiatry and Biobehavioral Sciences, Child and Adolescent Psychiatry, UCLA Semel Institute for Neuroscience and Human Behavior, Los Angeles, CA, USA., Pittenger C; Department of Psychiatry, Yale University, New Haven, CT, USA., Posthuma D; Department of Complex Trait Genetics, Vrije Universiteit Amsterdam, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, Amsterdam, The Netherlands.; Department of Child and Adolescent Psychiatric, Section Complex Trait Genetics, VU Medical Center Amsterdam, Amsterdam, The Netherlands., Ramos-Quiroga JA; Department of Psychiatry, Hospital Universitari Vall d'Hebron, Barcelona, Spain.; Group of Psychiatry, Mental Health and Addictions, Psychiatric Genetics Unit, Vall d'Hebron Research Institute (VHIR), Barcelona, Spain.; Biomedical Network Research Centre on Mental Health (CIBERSAM), Barcelona, Spain.; Department of Psychiatry and Forensic Medicine, Universitat Autònoma de Barcelona, Barcelona, Spain., Rasmussen SA; Department of Psychiatry & Human Behavior, Alpert Medical School, Brown University, Providence, RI, USA., Richter MA; Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, ON, Canada.; Department of Psychiatry, University of Toronto, Toronto, ON, Canada., Rosenberg DR; Department of Psychiatry and Behavioral Neurosciences, Child and Adolescent Psychiatry, Wayne State University School of Medicine, Detroit, MI, USA., Ruhrmann S; Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany., Samuels JF; Department of Psychiatry and Behavioral Sciences, The Johns Hopkins University School of Medicine, Baltimore, MD, USA., Sandin S; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Sandor P; Department of Psychiatry, University of Toronto, Toronto, ON, Canada., Spalletta G; Laboratory of Neuropsychiatry, IRCCS Santa Lucia Foundation, Rome, Italy.; Department of Psychiatry and Behavioral Sciences, Division of Neuropsychiatry, Baylor College of Medicine, Houston, TX, USA., Stein DJ; Dept of Psychiatry & Neuroscience Institute, SAMRC Unit on Risk & Reslience in Mental Disorders, University of Cape Town, Cape Town, Western Cape, South Africa., Stewart SE; Department of Psychiatry, University of British Columbia, Vancouver, BC, Canada.; British Columbia Children's Hospital Research Institute, Vancouver, BC, Canada.; British Columbia Mental Health and Substance Use Services Research Institute (BCMHSUS), Vancouver, BC, Canada., Storch EA; Department of Psychiatry and Behavioral Sciences, Baylor College of Medicine, Houston, TX, USA., Stranger BE; Department of Pharmacology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.; Center for Genetic Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Turiel M; Department of Cardiology, University of Milan, Milan, Italy., Werge T; Institute of Biological Psychiatry, Mental Health Center Sct. Hans, Copenhagen University Hospital, Mental Health Services (RHP), Copenhagen, Denmark.; Institute of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Andreassen OA; Institute of Clinical Medicine, NORMENT Centre, University of Oslo, Oslo, Norway.; Division of Mental Health and Addiction, Center for Precision Psychiatry, Oslo University Hospital, Oslo, , Norway., Børglum AD; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus University, Aarhus, Denmark.; Center for Genomics and Personalized Medicine, CGPM, Aarhus University, Aarhus, Denmark., Walitza S; Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital Zurich (PUK), University of Zurich, Zürich, Switzerland.; Neuroscience Center Zurich, University of Zurich and the ETH Zuric, Zurich, Switzerland.; Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland., Hveem K; HUNT Center for Molecular and Clinical Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; HUNT Research Center, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Research, Innovation and Education, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Hansen BK; Bergen Center for Brain Plasticity (BCBP), Psychiatry, Haukeland University Hospital, Bergen, Norway.; Centre for Crisis Psychology, Psychology, University of Bergen, Bergen, Norway., Rück CP; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Services, Region Stockholm , Stockholm, Sweden., Martin NG; Department of Genetic Epidemiology, QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Milani L; Estonian Genome Centre, Institute of Genomics, University of Tartu, Tartu, Estonia., Mors O; Psychosis Reasearch Unit, Aarhus University Hospital - Psychiatry, 8200 Aarhus N, Denmark., Reichborn-Kjennerud T; Department of Mental Disorders, Norwegian Institute of Public Health, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Ribasés M; Psychiatric Genetics Unit, Group of Psychiatry, Mental Health and Addiction, Vall d'Hebron Research Institute (VHIR), Universitat Autònoma de Barcelona, Barcelona, Spain.; Department of Mental Health, Hospital Universitari Vall d'Hebron , Barcelona, Spain.; Biomedical Network Research Centre on Mental Health (CIBERSAM), Madrid, Spain.; Department of Genetics, Microbiology, and Statistics, Faculty of Biology, Universitat de Barcelona (UB), Barcelona, Spain., Kvale G; Bergen Center for Brain Plasticity, Psychiatry, Haukeland University Hospital, Bergen, Norway.; Department of Clinical Psychology, Faculty of Psychology, University of Bergen, Bergen, Vestland., Mataix-Cols D; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Services, Region Stockholm , Stockholm, Sweden., Domschke K; Department of Psychiatry, University of Freiburg - Medical Faculty, Freiburg, Germany.; German Center for Mental Health (DZPG), Partner Site Berlin, Berlin, Germany., Grünblatt E; Department of Child and Adolescent Psychiatry and Psychotherapy, Psychiatric University Hospital Zurich (PUK), University of Zurich, Zürich, Schweiz.; Neuroscience Center Zurich, University of Zurich and the ETH Zuric, Zurich, Switzerland.; Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland., Wagner M; Departments of Psychiatry and Psychotherapy, University Hospital Bonn, Bonn, Germany., Zwart JA; Department of Research and Innovation, Clinical Neuroscience, Oslo University Hospital and University of Oslo, Oslo, Norway.; HUNT Center for Molecular and Clinical Epidemiology, Department of Public Health and Nursing, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway., Breen G; Social, Genetic, and Developmental Psychiatric Centre, Institute of Psychiatry, Psychology, and Neuroscience, King's College London, London, United Kingdom., Nestadt G; Department of Psychiatry and Behavioral Science, Johns Hopkins University, Baltimore, MD, USA., Kaprio J; Institute for Molecular Medicine FIMM, University of Helsinki, Helsinki, Finland., Arnold PD; Department of Psychiatry, The Mathison Centre for Mental Health Research & Education, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada.; Program in Genetics and Genome Biology, Hospital for Sick Children, Toronto, ON, Canada., Grice DE; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Knowles JA; Department of Genetics, Human Genetics Institute of New Jersey, Rutgers University, Piscataway, NJ, USA., Ask H; PsychGen Center for Genetic Epidemiology, Norwegian Institute of Public Health, Oslo, Norway.; PROMENTA Research Center, Department of Psychology, University of Oslo, Oslo, Norway., Verweij KJ; Department of Psychiatry, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands., Davis LK; Department of Medicine, Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Smit DJ; Department of Psychiatry, Amsterdam UMC location AMC, Amsterdam, The Netherlands., Crowley JJ; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.; Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet & Stockholm Health Services, Region Stockholm , Stockholm, Sweden., Scharf JM; Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, MA, USA., Stein MB; Psychiatry Service, VA San Diego Healthcare System, San Diego, CA, USA.; Department of Psychiatry and School of Public Health, University of California San Diego, La Jolla, CA, USA., Gelernter J; Department of Psychiatry, Human Genetics (Psychiatry), Yale University School of Medicine, West Haven, CT, USA.; Department of Psychiatry, Veterans Affairs Connecticut Healthcare Center, West Haven, CT, USA., Mathews CA; Psychiatry and Genetics Institute, Center for OCD, Anxiety and Related Disorders, University of Florida, Gainesville, FL, USA., Derks EM; Department of Mental Health and Neuroscience, QIMR Berghofer, Brisbane, Australia., Mattheisen M; Department of Community Health and Epidemiology and Faculty of Computer Science, Dalhousie University, Halifax, NS, Canada.; Department of Biomedicine, Aarhus University, Aarhus, Denmark.; Department of Psychiatric Phenomics and Genomics (IPPG), Ludwig-Maximilians University Munich, Munich, Germany.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Mar 13. Date of Electronic Publication: 2024 Mar 13.