Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Godwin Kumi"'
Autor:
Chan Gao, Michael Quigley, Dandan Zhao, Jennifer Koenitzer, Dan You, Stephen Hillerman, Gregory Locke, Charu Chaudhry, Caitlyn Stromko, Anwar Murtaza, Yi Fan, Yali Chen, Stephanie Briceno, Elizabeth Duperret, Johnni Gullo-Brown, John Feder, Joshua Curtin, Andrew P Degnan, Godwin Kumi, Mark Wittman, Benjamin M Johnson, Karen E Parrish, Giridharan Gokulrangan, John T Hunt, Luisa Salter-Cid, Emma Lees, Jinqi Liu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 1 (2021)
Background Hematopoietic progenitor kinase 1 (HPK1 or MAP4K1) has been demonstrated as a negative intracellular immune checkpoint in mediating antitumor immunity in studies with HPK1 knockout and kinase dead mice. Pharmacological inhibition of HPK1 i
Externí odkaz:
https://doaj.org/article/ca18b70501584617bef15c4ef9806fc2
Autor:
Zhi Liang, Alan Wilson, Li Dong, Neil T. Burford, David S. Kimball, Kenneth G. Carson, Yingzhi Bi, Yulian Zhang, Bireshwar Dasgupta, Carolyn Diane Dzierba, Richard A. Hartz, James E. Grace, G. Greg Zipp, Soojin Kwon, Martin A. Lewis, Joanne J. Bronson, Cynthia Anne Fink, Amr Nouraldeen, Saadat Aleem, Giovanni Cianchetta, Jiancheng Wang, Ying Liu, Vijay T. Ahuja, Robert L. Bertekap, Jianxin Han, Michael Alan Green, Angela Cacace, Godwin Kumi, Yudith Garcia, Ying Qiao, Meredith Ferrante, John E. Macor, Ryan Westphal
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:1448-1452
Small molecule modulators of GPR88 activity (agonists, antagonists, or modulators) are of interest as potential agents for the treatment of a variety of psychiatric disorders including schizophrenia. A series of phenylglycinol and phenylamine analogs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16bf15e7cd2cc6067dbe9746466df095
https://doi.org/10.1016/j.bmcl.2015.01.036
https://doi.org/10.1016/j.bmcl.2015.01.036
Autor:
Godwin Kumi, Benjamin W. Gung
Publikováno v:
The Journal of organic chemistry. 69(10)
The conjugated entriyne natural product, (S)-(E)-15,16-dihydrominquartynoic acid (1), is synthesized in five linear steps and 30% overall yield from the known aldehyde 11. The key step is a one-pot in situ desilylation/Cadiot-Chodkiewicz coupling rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb6708666e53ac2d9fc3a2a6864056e
https://pubmed.ncbi.nlm.nih.gov/15132560
https://pubmed.ncbi.nlm.nih.gov/15132560
Autor:
Godwin Kumi, Benjamin W. Gung
Publikováno v:
The Journal of organic chemistry. 68(15)
The conjugated tetraacetylenic natural product (S)-18-hydroxyminquartynoic acid (2) is synthesized in five linear steps and 17.7% overall yield from commercially available 1,2,5,6-O-diisopropylidene mannitol. The key step is a one-pot three-component
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f29c22b13db552e1f6054aa5b1fb65de
https://pubmed.ncbi.nlm.nih.gov/12868932
https://pubmed.ncbi.nlm.nih.gov/12868932
Autor:
John A. Lowe, Dennis Liotta, Andrew A. Bolinger, Noelle C. Anastasio, Kathryn A. Cunningham, Jia Zhou, Craig E. Stivala, Domagoj Vucic, Todd Fields, Eric M. Woerly, Michael G. Bell, Kyle W. Sloop, Joseph D. Ho, David C. Ebner, Gregory J. Tesz, Kentaro Futatsugi, Silvana Leit, Bhaskar Srivastava, Nathan E. Genung, Joshua J. McElwee, Denise Levasseur, Scott D. Edmondson, Darren Finkelstein, Timothy D. Machajewski, Nicolas Desroy, Christophe Peixoto, Steve De Vos, Natalie Holmberg-Douglas, Hunter Shunatona, Godwin Kumi, Ashok Purandare, Christopher R. Smith, Matthew A. Marx, Kevin D. Freeman-Cook, Robert L. Hoffman, M. Alejandro Valdes-Pena, Joshua G. Pierce, Nishant Sarkar, Jonathan M. Stokes, María-Jesús Pérez-Pérez, Eva-María Priego, Miguel A. Martín-Acebes, Hasane Ratni, Kathleen D. McCarthy, Joseph L. Duffy, Sergey V. Paushkin, Sivaraman Dandapani, George S. Tria, Joseph W. Tucker, Mary E. Spilker, Brooke A. Conti, Mariano Oppikofer, Emily C. Cherney, David K. Williams, Liping Zhang, Susheel J. Nara, Anh T. Tran, James J. Crawford, Debashis
