Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Godswill C. Onunkwo"'
Autor:
Calister E Ugwu, Chukwuma O Agubata, Salome A Chime, Nicholas C Obitte, Ikechukwu V Onyishi, Godswill C Onunkwo, Sabinus I Ofoefule, Amarauche Chukwu
Publikováno v:
Tropical Journal of Pharmaceutical Research; Vol. 21 No. 11 (2022); 2285-2293
Purpose: To develop modified hard gelatin capsules (MHGCs) for colon-specific delivery of hydrogel-based piroxicam microparticles. Methods: Solvent evaporation technique was adopted for the microencapsulation of piroxicam using liquid paraffin (PL.MP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00e9b24ef74fa046f53e0362de03e3d7
https://www.ajol.info/index.php/tjpr/article/view/241485
https://www.ajol.info/index.php/tjpr/article/view/241485
Autor:
Simeon U. Onoja, John-Dike Nwabueze Ogbonna, Adaeze Chidiebere Echezona, Ifeanyi T. Nzekwe, Paul A. Akpa, Obialunamma C. Metu, Godswill C. Onunkwo, Anthony A. Attama, Petra O. Nnamani
Publikováno v:
Tropical Journal of Pharmaceutical Research. 19:1341-1349
Purpose: To increase the solubility of artemether (ART) in Transcutol® HP through microencapsulation in sodium alginate polymer to achieve sustained in vivo release.Method: Graded concentrations of ART (0.00, 0.25, 0.50, 0.75, and 1.00 g) microcapsu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65789d42c12e56fefccc3b9af8834ca7
https://doi.org/10.4314/tjpr.v19i7.1
https://doi.org/10.4314/tjpr.v19i7.1
Publikováno v:
Current HIV Research. 18:237-247
Background: Lipid based formulations have been confirmed to lower some side effects of drug and can be tailor made to offer sustained drug release of drugs with short half-life like stavudine. Aim: To evaluate the immunomodulatory properties of stavu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d91dfc50102e4d2b109f444c7dfd726f
https://doi.org/10.2174/1570162x18666200510010738
https://doi.org/10.2174/1570162x18666200510010738
Autor:
Chukwuma O. Agubata, Blessing B. Nta, Sabinus Ofoefule, Parker E. Joshua, Godswill C. Onunkwo, Remigius I. Onoja
Publikováno v:
Journal of Drug Delivery and Therapeutics. 10:125-132
Background: Chlorpheniramine is an antihistamine that is used in the treatment of rhinitis and other allergies. Objectives: The objectives of this research was to develop and evaluate transdermal patches for improved delivery of chlorpheniramine in i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bbad990025763e1ffa4029f3cda8837
https://doi.org/10.22270/jddt.v10i4.4163
https://doi.org/10.22270/jddt.v10i4.4163
Publikováno v:
Infectious Disorders - Drug Targets. 20:76-87
Background: Stavudine is an antiretroviral therapy with so many side effects and has a short half-life of 1.5 h. It degrades to thymine under hydrolytic, oxidative and photolytic conditions hence has major formulation challenges. Objectives: To formu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b1dbffdd7530620925644864218033c
https://doi.org/10.2174/1871526519666190313162635
https://doi.org/10.2174/1871526519666190313162635
Publikováno v:
Journal of Current Pharma Research. 5:1411-1424
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa5c9e264cee902df2da108e4787012f
https://doi.org/10.33786/jcpr.2015.v05i02.005
https://doi.org/10.33786/jcpr.2015.v05i02.005
Autor:
Chukwuma O. Agubata, Christel C. Mueller-Goymann, Godswill C. Onunkwo, Ifeanyi T. Nzekwe, Anthony A. Attama
Publikováno v:
International Journal of Pharmaceutics. 478:202-222
The anti-malarial activity of artemether is dependent on its bioavailability. The purpose of the research is to improve the solubility, bioavailability and therapeutic efficacy of lipophilic artemether using homolipid-based microparticles. Irvingia f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74b8d23102eb571b7fd715b8957b5528
https://doi.org/10.1016/j.ijpharm.2014.11.044
https://doi.org/10.1016/j.ijpharm.2014.11.044
Autor:
J. D. N. Ogbonna, S. A. Brown, K.I. Chukwu, C.O. Ugwu, Godswill C. Onunkwo, Chukwuma O. Agubata, K.A. Nnalue, Salome A. Chime
Publikováno v:
Journal of Drug Delivery Science and Technology. 24:519-524
The objective of this work was to develop direct compression matrix sustained-release tablets of diphenhydramine HCl and theophylline hydrate using Colocasia antiquorum gum (CAG) extracted by cold maceration as binder. Phytochemical characteristics o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fab50169dcd5247d6c0bf93a5b3cc666
https://doi.org/10.1016/s1773-2247(14)50098-6
https://doi.org/10.1016/s1773-2247(14)50098-6
Autor:
Salome A. Chime, Emmanuel Chukwuebuka Umeyor, Anthony A. Attama, Godswill C. Onunkwo, V. I. Onyishi
Publikováno v:
Indian Journal of Pharmaceutical Sciences
The objective of our work was to study the micromeritic properties of lyophilized diclofenac potassium-loaded lipospheres and to evaluate in vivo, the analgesic properties of diclofenac potassium in the lipospheres in addition to other in vitro prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6c666827589954d6d5c274793568d31
http://europepmc.org/articles/PMC3783748
http://europepmc.org/articles/PMC3783748
Publikováno v:
Journal of Drug Delivery Science and Technology. 22:485-492
Solidified reverse micellar solutions (SRMS) were formulated using phospholipid (Phospholipon 90H) and triglyceride (Softisan 154) in the ratios of 1:1, 2:1 and 1:2, respectively. SLMs were prepared by melt homogenization technique. Characterization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99ed59fd4bafb09e5192b871411b601f
https://doi.org/10.1016/s1773-2247(12)50085-7
https://doi.org/10.1016/s1773-2247(12)50085-7