Cigarette smoke-induced transgenerational alterations in genome stability in cord blood of human F1 offspring

Autor: Laubenthal, Julian, Zlobinskaya, O., Poterlowicz, Krzysztof, Baumgartner, Adolf, Gdula, Michal R., Fthenou, E., Keramarou, M., Hepworth, S.J., Kleinjans, J.C., van Schooten, F.J., Brunborg, G., Godschalk, R.W., Schmid, Thomas E., Anderson, Diana

The relevance of preconceptional and prenatal toxicant exposures for genomic stability in offspring is difficult to analyze in human populations, because gestational exposures usually cannot be separated from preconceptional exposures. To analyze the

Externí odkaz: http://hdl.handle.net/10454/6063

Polyunsaturated fatty acid levels at birth and child-to-adult growth: Results from the MEFAB cohort

Autor: Stratakis, N., Gielen, M., Margetaki, K., Godschalk, R.W., van der Wurff, I., Rouschop, S., Ibrahim, A., Antoniou, E., Chatzi, L., de Groot, R.H.M., Zeegers, M.P.

Publikováno v: In Prostaglandins, Leukotrienes and Essential Fatty Acids November 2017 126:72-78

Bulky DNA Adducts in White Blood Cells: A Pooled Analysis of 3,600 Subjects

Autor: Ricceri, F., Godschalk, R.W., Peluso, M., Phillips, D.H., Agudo, A, Georgiadis, P., Loft, S., Tjonneland, A., Raaschou-Nielsen, O., Palli, D., Perera, F., Vermeulen, R., Taioli, E., Sram, R.J., Munnia, A., Rosa, F., Allione, A., Matullo, G., Vineis, P., Risk Assessment of Toxic and Immunomodulatory Agents, Dep IRAS

Publikováno v: Cancer Epidemiology Biomarkers & Prevention
Cancer Epidemiology Biomarkers & Prevention, 19(12), 3174. American Association for Cancer Research Inc.

Background: Bulky DNA adducts are markers of exposure to genotoxic aromatic compounds, which reflect the ability of an individual to metabolically activate carcinogens and to repair DNA damage. Polycyclic aromatic hydrocarbons (PAHs) represent a majo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1104a982dfc7a07a3a318efc72153f8

Gene-diet interactions in exposure to heterocyclic aromatic amines and bulky DNA adduct levels in blood leukocytes

Autor: Ho, V., Peacock, S., Massey, T.E., Godschalk, R.W., van Schooten, F.J., Chen, J., King, W.D.

Publikováno v: Environmental and Molecular Mutagenesis, 56(7), 609-620. Wiley

Heterocyclic aromatic amines (HAAs), carcinogens produced in meat when cooked at high temperatures, are an emerging biologic explanation for the meat-colorectal cancer relationship. HAAs form DNA adducts; left unrepaired, adducts can induce mutations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::547b0a0e6c93a654012b6de84848ce8a
https://cris.maastrichtuniversity.nl/en/publications/20539eb7-c455-48b6-a816-2e209228768a

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