Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Godfried W. van der Heijden"'
Autor:
Valeriya Gaysinskaya, Brendan F. Miller, Chiara De Luca, Godfried W. van der Heijden, Kasper D. Hansen, Alex Bortvin
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-15 (2018)
Abstract Background Meiosis is a specialized germ cell cycle that generates haploid gametes. In the initial stage of meiosis, meiotic prophase I (MPI), homologous chromosomes pair and recombine. Extensive changes in chromatin in MPI raise an importan
Externí odkaz:
https://doaj.org/article/88cde53dca7447c987a8be8be5eff3f5
Autor:
Liina Nagirnaja, Kristian Almstrup, Sofia B. Winge, Donald F. Conrad, Kenneth I. Aston, Filipa Carvalho, Peter N. Schlegel, Nina Mørup, Niels E. Skakkebæk, Alexandra M. Lopes, Niels Jørgensen, C. Joana Marques, Francesca Khani, Ieva Golubickaite, John E. Nielsen, Manon S. Oud, Ewa Rajpert-De Meyts, Joris A. Veltman, Rytis Stakaitis, Godfried W. van der Heijden
Publikováno v:
The New England Journal of Medicine, 385, 707-719
Nagirnaja, L, Mørup, N, Nielsen, J E, Stakaitis, R, Golubickaite, I, Oud, M S, Winge, S B, Carvalho, F, Aston, K I, Khani, F, Van Der Heijden, G W, Marques, C J, Skakkebaek, N E, Rajpert–de Meyts, E, Schlegel, P N, Jørgensen, N, Veltman, J A, Lopes, A M, Conrad, D F & Almstrup, K 2021, ' Variant PNLDC1, Defective piRNA Processing, and Azoospermia ', New England Journal of Medicine, vol. 385, no. 8, pp. 707-719 . https://doi.org/10.1056/NEJMoa2028973
The New England Journal of Medicine, 385, 8, pp. 707-719
Nagirnaja, L, Mørup, N, Nielsen, J E, Stakaitis, R, Golubickaite, I, Oud, M S, Winge, S B, Carvalho, F, Aston, K I, Khani, F, Van Der Heijden, G W, Marques, C J, Skakkebaek, N E, Rajpert–de Meyts, E, Schlegel, P N, Jørgensen, N, Veltman, J A, Lopes, A M, Conrad, D F & Almstrup, K 2021, ' Variant PNLDC1, Defective piRNA Processing, and Azoospermia ', New England Journal of Medicine, vol. 385, no. 8, pp. 707-719 . https://doi.org/10.1056/NEJMoa2028973
The New England Journal of Medicine, 385, 8, pp. 707-719
Item does not contain fulltext BACKGROUND: P-element-induced wimpy testis (PIWI)-interacting RNAs (piRNAs) are short (21 to 35 nucleotides in length) and noncoding and are found almost exclusively in germ cells, where they regulate aberrant expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b28d06724b7f000a35e3361fb2466c6
https://doi.org/10.1056/nejmoa2028973
https://doi.org/10.1056/nejmoa2028973
Autor:
Antoni Riera-Escamilla, Matthias Vockel, Liina Nagirnaja, Miguel J. Xavier, Albert Carbonell, Daniel Moreno-Mendoza, Marc Pybus, Ginevra Farnetani, Viktoria Rosta, Francesca Cioppi, Corinna Friedrich, Manon S. Oud, Godfried W. van der Heijden, Armin Soave, Thorsten Diemer, Elisabet Ars, Josvany Sánchez-Curbelo, Sabine Kliesch, Moira K. O’Bryan, Eduard Ruiz-Castañe, Fernando Azorín, Joris A. Veltman, Kenneth I. Aston, Donald F. Conrad, Frank Tüttelmann, Csilla Krausz
Publikováno v:
American Journal of Human Genetics, 109, 1458-1471
American Journal of Human Genetics, 109, 8, pp. 1458-1471
AMERICAN JOURNAL OF HUMAN GENETICS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Am J Hum Genet
American Journal of Human Genetics, 109, 8, pp. 1458-1471
AMERICAN JOURNAL OF HUMAN GENETICS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Am J Hum Genet
Although the evolutionary history of the X chromosome indicates its specialization in male fitness, its role in spermatogenesis has largely been unexplored. Currently only three X chromosome genes are considered of moderate-definitive diagnostic valu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b161d8ffe4e99ebcb9376fce2f507b0
http://hdl.handle.net/2066/282690
http://hdl.handle.net/2066/282690
Autor:
Godfried W. van der Heijden, Kasper D. Hansen, Valeriya Gaysinskaya, Alex Bortvin, Brendan F. Miller, Chiara De Luca
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-15 (2018)
Epigenetics & Chromatin, 11:15. BioMed Central Ltd.
Epigenetics & Chromatin
Epigenetics & Chromatin, 11:15. BioMed Central Ltd.
Epigenetics & Chromatin
Background Meiosis is a specialized germ cell cycle that generates haploid gametes. In the initial stage of meiosis, meiotic prophase I (MPI), homologous chromosomes pair and recombine. Extensive changes in chromatin in MPI raise an important questio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f24e2a978ab1e074e13805f60c0737d3
http://link.springer.com/article/10.1186/s13072-018-0186-0
http://link.springer.com/article/10.1186/s13072-018-0186-0
Autor:
Leonidas Magarakis, Esther Sleddens-Linkels, Godfried W. van der Heijden, Joost Gribnau, Wiggert A. van Cappellen, Maureen Eijpe, Aristea Magaraki, Willy M. Baarends, Antoine H.F.M. Peters
Publikováno v:
Epigenetics & Chromatin, 10:11. BioMed Central Ltd.
Epigenetics & Chromatin
Epigenetics & Chromatin
Background In the nuclei of most mammalian cells, pericentric heterochromatin is characterized by DNA methylation, histone modifications such as H3K9me3 and H4K20me3, and specific binding proteins like heterochromatin-binding protein 1 isoforms (HP1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364f8bb2837cca86a53a7b1a872ddf26
https://pure.eur.nl/en/publications/28dc360b-6d9c-4ae1-b65e-8a4504794e80
https://pure.eur.nl/en/publications/28dc360b-6d9c-4ae1-b65e-8a4504794e80
Autor:
Ali Sarkeshik, Godfried W. van der Heijden, Julio Castañeda, Pavol Genzor, John R. Yates, Nicholas T. Ingolia, Alex Bortvin
Publikováno v:
The EMBO Journal. 33:1999-2019
Pachytene piRNAs are a class of Piwi-interacting small RNAs abundant in spermatids of the adult mouse testis. They are processed from piRNA primary transcripts by a poorly understood mechanism and, unlike fetal transposon-derived piRNAs, lack complem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7fa7649508273c2d9c4b7f91dff5f7e8
https://doi.org/10.15252/embj.201386855
https://doi.org/10.15252/embj.201386855
Publikováno v:
Cytometry Part A. 85:556-565
Meiotic prophase I (MPI), is an initial stage of meiosis characterized by intricate homologous chromosome interactions, synapsis, and DNA recombination. These processes depend on the complex, but poorly understood early MPI events of homologous chrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e459ddf56774f862b50b82c1c60c6cc
https://doi.org/10.1002/cyto.a.22463
https://doi.org/10.1002/cyto.a.22463
Publikováno v:
Genes, Vol 1, Iss 3, Pp 505-520 (2010)
Genes
Genes; Volume 1; Issue 3; Pages: 505-520
Genes
Genes; Volume 1; Issue 3; Pages: 505-520
Meiosis yields haploid gametes following two successive divisions of a germ cell in the absence of intervening DNA replication. Balanced segregation of homologous chromosomes in Meiosis I is aided by a proteinaceous structure, the synaptonemal comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ec4b3683d28bb5697ad0def6375087
https://doi.org/10.3390/genes1030505
https://doi.org/10.3390/genes1030505
Publikováno v:
Epigenetics. 4:76-79
Postmigratory mouse primordial germ cells (PGCs) undergo extensive epigenetic remodeling that includes DNA methylation (DM) reprogramming of imprinted genes and, surprisingly, of transposable elements (TEs). Given the danger posed by TEs to the integ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::202aa0976da1c4ff327585a6e5e762d8
https://doi.org/10.4161/epi.4.2.7783
https://doi.org/10.4161/epi.4.2.7783
Autor:
Katarina Gell, Sigrid Eckardt, Godfried W. van der Heijden, K. John McLaughlin, Chengtao Her, N. Adrian Leu, Peijing Jeremy Wang, David C. Page, Ricardo Benavente, Christer Höög, Fang Yang
Publikováno v:
Genes & Development. 22:682-691
Meiotic silencing of sex chromosomes may cause their depletion of meiosis-specific genes during evolution. Here, we challenge this hypothesis by reporting the identification of TEX11 as the first X-encoded meiosis-specific factor in mice. TEX11 forms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6628f5eed4716b22434cc22703e4b38a
https://doi.org/10.1101/gad.1613608
https://doi.org/10.1101/gad.1613608